1219-5
LW Ag [Presence] on Red Blood Cells
Active
Part Descriptions
LP15216-2 LW
The LW and D antigens are closely related. Rh+ red cells express LW more strongly than Rh negative cells. The early nomenclature tried to accommodate this observation by using a numerical system; eg. LW1, LW2, etc. but this changed following Sistonen's report of a new low frequency antigen called Ne^a which was found in ~5% of Finns. Because further work suggested that the Ne^a gene was allelic to LW, they were renamed LW^a and LW^b (Ne^a). Thus, the null phenotype for this system would be LW(a-b-) which is extremely rare and is the result of a partial gene deletion. A transient or acquired form of LW(a-b-) has been reported and these individuals are found because they produce a transient anti-LW. Some (but not all) examples have been associated with terminal illnesses such as Hodgkin's disease, leukemia, sarcomas or other malignancies.
Source: Serum, Cells and Rare Fluid Exchange, LW
LP15216-2 LW
Although genetically independent of the Rh system, the Landsteiner Wiener (LW) blood group antigen system is part of the Rh protein cluster and is expressed more strongly on D positive cells. There are 2 antithetical alleles, LW^a and LW^b with 4 possible phenotypes: LW(a+b-), LW(a-b+), LW(a+b+), and LW(a-b-).(Schenkel-Brunner H. (2000) Landsteiner-Wiener System. In: Human Blood Groups. Springer, Vienna) LW^a has much higher prevalence than LW^b in most populations. Hemolytic disease of the newborn due to anti-LW is rare and mild when it does occur [https://en.wikipedia.org/wiki/ICAM4].
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- LW Ag
- Property
- PrThr
- Time
- Pt
- System
- RBC
- Scale
- Ord
- Method
Additional Names
- Short Name
- LW Ag RBC Ql
- Display Name
- LW Ag Ql (RBC)
- Consumer Name Alpha Get Info
- LW antigen, Red blood cells
Basic Attributes
- Class
- BLDBK
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 93914-0 | Blood group antigens panel - Red Blood Cells |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-AR | Spanish (Argentina) | [antígeno] LW [Ag]: |
| es-ES | Spanish (Spain) | Grupo sanguíneo LW Antígeno: |
| es-MX | Spanish (Mexico) | LW Ag: |
| et-EE | Estonian (Estonia) | LW antigeen: Synonyms: Erütrotsüüdid Järgarvuline Juhuslik |
| fr-CA | French (Canada) | LW, Ag: |
| fr-FR | French (France) | LW antigène: |
| fr-BE | French (Belgium) | LW Ag: Synonyms: Antigène |
| it-IT | Italian (Italy) | LW, Ag: Synonyms: Banca del sangue Globuli rossi Presenza o Soglia Punto nel tempo (episodio) |
| ko-KR | Korean (Korea, Republic Of) | LW 항원: |
| nl-NL | Dutch (Netherlands) | LW Ag: Synonyms: antigeen rode bloedcellen |
| pt-BR | Portuguese (Brazil) | LW Ag: Synonyms: Landsteiner-Wiener; |
| ru-RU | Russian (Russian Federation) | LW Аг: Synonyms: Порядковый Точка во времени; |
| tr-TR | Turkish (Turkey) | LW Ag: Synonyms: Antijen Mevcut RBC |
| zh-CN | Chinese (China) | LW 抗原: Synonyms: Ag Landsteiner-Wiener (LW); |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=1219-5
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright