1350-8
Yt sup(b) Ab [Presence] in Serum or Plasma
Active
Part Description
LP15250-1 Y little t super little b
The two antigens of the Yt system, Yt^a and Yt^b, are both expressed at birth, however in a slightly lower expression level than seen on adult cells. They were shown to be resistant to trypsin treatment, but sensitive to other protein cleaving enzymes. Antibodies to these antigens were implicated in cases of delayed transfusion reactions but were not reported to have caused hemolytic disease of the newborn. No examples of Yt(a-b-) individuals have been found despite numerous studies. From population studies, Yt^b appeared to be lacking, or of very low incidence, from Orientals, Amer-Indians and southern Africans; Yta was found lacking in approximately one per thousand individuals of European origin.
This system remained unexciting until it was found that both of these antigens were weak or absent from paroxysmal nocturnal hemoglobinuria (PNH) III red blood cells. With a rush of activity in the early 1990's, it was found that the Yt blood group system antigens represented amino acid substitutions on the GPI-linked glycoprotein, acetylcholinesterase (AchE). This protein probably exists as a dimer (pair) in the red cell membrane. Yta and Ytb are equated to substitutions of a hisitidine and asparagine, respectively, at amino acid position 322 on the GPI-linked glycoprotein. AChE has been assigned a chromosome location at 7q22.
Source: Serum, Cells and Rare Fluid Exchange
, Yt^a
Fully-Specified Name
- Component
- Y little t super little b Ab
- Property
- PrThr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Ord
- Method
Additional Names
- Long Common Name
- Yt sup(b) Ab [Presence] in Serum or Plasma
- Short Name
- Yt sup(b) Ab SerPl Ql
- Display Name
- Yt sup(b) Ab Ql
- Consumer Name Alpha Get Info
- Yt sup(b) antibody, Blood
Basic Attributes
- Class
- BLDBK
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.56 (MIN)
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Observation
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Υ πεζό t εκθέτης πεζό b Αντίσωμα: Synonyms: PrThr |
es-AR | Spanish (Argentina) | [anticuerpo anti - ] Y [minúscula] T [superíndice] [minúscula] B [Ac]: |
es-ES | Spanish (Spain) | Ytb Anticuerpos: |
es-MX | Spanish (Mexico) | Y sub t super sub b Ab: |
et-EE | Estonian (Estonia) | Yt^b antikehad: Synonyms: Järgarvuline Juhuslik Plasma Seerum Seerum või plasma |
fr-CA | French (Canada) | Y petit t exposant petit b, Ac: |
fr-FR | French (France) | YT2 (Ytb) anticorps: |
fr-BE | French (Belgium) | Y petit t exposant petit b Ac: Synonyms: Anticorps |
it-IT | Italian (Italy) | Y t minuscola apice b Ab: Synonyms: anticorpo Banca del sangue Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Yt^b |
ko-KR | Korean (Korea, Republic Of) | Yt^b 항체: |
nl-NL | Dutch (Netherlands) | Y kleine t super kleine b As: Synonyms: antistof; |
pt-BR | Portuguese (Brazil) | Y t pequeno b pequeno superior Ac: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Y малое t супер малое b Ат: Synonyms: Антитело Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | Y küçük t süper küçük b Ab: Synonyms: Mevcut |
zh-CN | Chinese (China) | Yt^b 抗体: Synonyms: Ab; |
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- CodeSystem lookup
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