13777-8
Methylsuccinate/Creatinine [Mass Ratio] in Urine
Active
Part Descriptions
LP18443-9 Methylsuccinate
Methylsuccinic acid is a normal metabolite found in human fluids. Increased urinary levels of Methylsuccinic acid (together with ethylmalonic acid) are the main biochemical measurable features in ethylmalonic encephalopathy [OMIM: 602473], a rare metabolic disorder with an autosomal recessive mode of inheritance that is clinically characterized by neuromotor delay, hyperlactic acidemia, recurrent petechiae, orthostatic acrocyanosis, and chronic diarrhea. PMID: 12382164
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database,
Human Metabolome Database (Methylsuccinic acid)
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database,
Creatinine
LOINC Names Get Info
- Fully-Specified Name
- Methylsuccinate/Creatinine:
MRto: Pt: Urine: Qn: - Long Common Name
- Methylsuccinate/Creatinine [Mass Ratio] in Urine
- Short Name
- Me-succinate/Creat Ur
- Display Name
- Methylsuccinate/Creatinine (U) [Mass ratio]
- Consumer Name Alpha Get Info
- Methylsuccinate/Creatinine, Urine
Part Model Get Info
- Component
- Methylsuccinate/Creatinine
LP286536-0
- Analyte
- Methylsuccinate/Creatinine
LP286536-0
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- MRto
LP6834-8
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- Urine
LP7681-2
- System Core
- Urine
LP7681-2
- Super System
- NULL
- Scale
- Qn
LP7753-9
- Method
- NULL
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0k
- Last Updated
- Version 2.73 (MIN)
- Change Reason
- This term was Discouraged in a previous release because at the time (2013), this analyte was not being measured in mass units. We are changing the term back to Active status because at least two major laboratories are currently (in 2018) measuring this analyte in mass units.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 6952
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 50334-2 | Acylglycines panel [Mass Ratio] - Urine |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Methylsukcinát/kreatinin: |
| el-GR | Greek (Greece) | Μεθυλοηλεκτρικό οξύ/Κρεατινίνη: Synonyms: CHEM MRto Pt Qn Κρεατινίνη Μεθυλοηλεκτρικό οξύ Ούρα |
| es-AR | Spanish (Argentina) | metilsuccinato/creatinina: |
| es-ES | Spanish (Spain) | Metilsuccinato/Creatinina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Succinato de metilo / creatinina: |
| et-EE | Estonian (Estonia) | Metüülsuksinaat/kreatiniin: Synonyms: Juhuslik Kvantitatiivne Uriin |
| fr-CA | French (Canada) | Méthylsuccinate/Créatinine: |
| fr-BE | French (Belgium) | Méthylsuccinate/Créatinine: Synonyms: Rapport de masse |
| fr-FR | French (France) | 2-méthylsuccinate/créatinine: |
| it-IT | Italian (Italy) | Metilsuccinato/Creatinina: Synonyms: Chimica Punto nel tempo (episodio) Rapporto di Massa |
| ko-KR | Korean (Korea, Republic Of) | 메틸숙시네이트/크레아티닌: |
| nl-NL | Dutch (Netherlands) | methylsuccinaat/creatinine: Synonyms: kreatinine |
| pt-BR | Portuguese (Brazil) | Metilsuccinato/Creatinina: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Метилсукцинат/Креатинин: Synonyms: Количественный Масс отношение Точка во времени; |
| tr-TR | Turkish (Turkey) | Metilsüksinat/Kreatinin: |
| zh-CN | Chinese (China) | 甲基琥珀酸/肌酐: Synonyms: 2-甲基丁二酸; |
Example Units
| Unit | Source |
|---|---|
| mcg/mg cr | REGENSTRIEF |
| mg/gm cr | REGENSTRIEF |
| mg/g{creat} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://