13819-8
Uracil/Creatinine [Mass Ratio] in Urine
Active
Part Descriptions
LP18455-3 Uracil
Uracil is a common and naturally occurring pyrimidine derivative. It is a planar, unsaturated compound that has the ability to absorb light.
Uracil's use in the body is to help carry out the synthesis of many enzymes necessary for cell function through bonding with riboses and phosphates. Uracil serves as allosteric regulator and coenzyme for reactions in the human body and in plants. UMP controls the activity of carbamoyl phosphate synthetase and aspartate transcarbamoylase in plants, while UDP and UTP requlate CPSase II activity in animals. UDP-glucose regulates the conversion of glucose to galactose in the liver and other tissues in the process of carbohydrate metabolism. Uracil is also involved in the biosynthesis of polysaccharides and the transportation of sugars containing aldehydes.
It can also increase the risk for cancer in cases in which the body is extremely deficient in folate. The deficiency in folate leads to increased ratio of deoxyuracilmonophosphates (dUMP)/deoxythyminemonophosphates (dTMP) and uracil misincorporation into DNA and eventually low production of DNA.
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Source: Wikipedia, Wikipedia
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- Uracil/Creatinine
- Property
- MRto
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Short Name
- Uracil/Creat Ur
- Display Name
- Uracil/Creatinine (U) [Mass ratio]
- Consumer Name Alpha Get Info
- Uracil/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0k
- Last Updated
- Version 2.42
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-AR | Spanish (Argentina) | uracilo/creatinina: |
| es-ES | Spanish (Spain) | Uracilo/Creatinina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Uracilo / Creatinina: |
| et-EE | Estonian (Estonia) | Uratsüül/kreatiniin: Synonyms: Juhuslik Kvantitatiivne Uriin |
| fr-CA | French (Canada) | Uracil/Créatinine: |
| fr-FR | French (France) | Uracile/créatinine: |
| fr-BE | French (Belgium) | Uracile/Créatinine: Synonyms: Rapport de masse |
| it-IT | Italian (Italy) | Uracile/Creatinina: Synonyms: Chimica Punto nel tempo (episodio) Rapporto di Massa |
| ko-KR | Korean (Korea, Republic Of) | 우라실/크레아티닌: |
| nl-NL | Dutch (Netherlands) | uracil/creatinine: Synonyms: kreatinine |
| pt-BR | Portuguese (Brazil) | Uracil/Creatinina: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Урацил/Креатинин: Synonyms: Количественный Масс отношение Точка во времени; |
| tr-TR | Turkish (Turkey) | Urasil/Kreatinin: |
| zh-CN | Chinese (China) | 尿嘧啶/肌酐: Synonyms: CR; |
Example Units
| Unit | Source |
|---|---|
| ng/g{creat} | Example UCUM Units |
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