LOINC
Version 2.73

13964-2Methylmalonate [Moles/volume] in Serum or PlasmaActive

Part Description

LP15735-1   Methylmalonate
Methylmalonate (methylmalonic acid) is measured as a second-tier assay when abnormal propionyl carnitine or methionine concentrations are identified in a primary newborn screening. Methylmalonic acidemia (MMA) and propionic acidemia (PA) are defects of propionate metabolism caused by deficiencies in methylmalonyl-CoA mutase and propionyl-CoA carboxylase, respectively. The clinical phenotype of both conditions includes vomiting, hypotonia, lethargy, apnea, hypothermia, and coma. The biochemical phenotype for MMA includes elevated methylmalonic acid, propionyl carnitine and methylcitric acid, while patients with PA have elevated propionyl carnitine and methylcitric acid with normal methylmalonic acid concentrations as the enzymatic defect is upstream of methylmalonic-CoA mutase. Source: Regenstrief LOINC

Fully-Specified Name

Component
Methylmalonate
Property
SCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Methylmalonate SerPl-sCnc
Display Name
Methylmalonate [Moles/Vol]
Consumer Name Alpha
Methylmalonate, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0k
Last Updated
Version 2.73
Order vs. Observation
Both
Common US Lab Results Rank
1030
Common Orders Rank
296

Member of these Groups

LG47301-3 Methylmalonate|Pt|Ser/Plas|118.088 g/mole

Language Variants Get Info

zh-CNChinese (China)
甲基丙二酸:物质的量浓度:时间点:血清/血浆:定量型:
nl-NLDutch (Netherlands)
methylmalonaat:mol/volume:moment:serum of plasma:kwantitatief:
et-EEEstonian (Estonia)
Metüülmalonaat:SCnc:Pt:S/P:Qn:
fr-BEFrench (Belgium)
Méthylmalonate:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-CAFrench (Canada)
Méthylmalonate:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FRFrench (France)
Méthylmalonate:Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:
de-DEGerman (Germany)
Methylmalonat:Stoffmengenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:
el-GRGreek (Greece)
Μεθυλμαλονικό:Συγκέντρωση ουσίας:Χρονική στιγμή:Ορός/Πλάσμα:Ποσοτική:
it-ITItalian (Italy)
Metilmalonato:SCnc:Pt:Siero/Plasma:Qn:
ko-KRKorean (Korea, Republic of)
메틸말로네이트:물질농도:검사시점:혈청/혈장:정량:
pt-BRPortuguese (Brazil)
Metilmalonato:SCnc:Pt:Sor/Plas:Qn:
ru-RURussian (Russian Federation)
Метилмалонат:МолКонц:ТчкВрм:Сыв/Плаз:Колич:
es-ARSpanish (Argentina)
metilmalonato:concentración de sustancia:punto en el tiempo:suero/plasma:cuantitativo:
es-MXSpanish (Mexico)
Malonato de metilo:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:
es-ESSpanish (Spain)
Metilmalonato:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:
tr-TRTurkish (Turkey)
Metilmalonat:SubKons:Zmlı:Ser/Plaz:Kant:

Example Units

Unit Source
umol/L eCHN
nmol/L;umol/L Example UCUM Units
mcmol/L REGENSTRIEF
nmol/L REGENSTRIEF

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=13964-2