Version 2.78

Part Description

LP32135-3   Prealbumin
Transthyretin (TTR) (originally called prealbumin or thyroxine-binding prealbumin) is a homotetrameric unglycosylated tryptophan rich protein that carries the thyroid hormones T3 and T4, and retinol in serum and CSF. Synthesized in hepatocytes, TTR and has a molar mass of 55000 daltons. At a pH of 8.6, an electrophoretic band appears prior to albumin in a relative amount of < 2.5 % due to its greater rate of diffusion to the anode. Its function is to bind and transport low molecular weight retinol-binding proteins, preventing their glomerular filtration. 30 50 % of circulating TTR is complexed by retinol-binding protein. Additionally, it binds and transports thyroxine (T4), nevertheless its affinity to this hormone is less than that of thyroxine binding globulin. TTR is decreased in hepatocellular synthesis caused by acute liver damage, or dietary protein deficiency, and because of its short half life (approximately 2 days) is used as a surrogate marker of nutritional status. TTR is also a negative acute phase reactive protein and levels decrease in inflammatory states. Levels can be elevated in chronic renal failure, high concentrations of corticosteroids, and Hodgkin's disease. TTR misfolding and aggregation is known to be associated with the amyloid diseases, senile systemic amyloidosis (SSA), familial amyloid polyneuropathy (FAP), and familial amyloid cardiomyopathy (FAC) [Tietz] Source: Regenstrief LOINC, Wikipedia: Transthyretin

Fully-Specified Name

Component
Thyroxine.prealbumin bound/Prealbumin
Property
MRto
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
T4 PA Bnd/Prealb SerPl
Display Name
T4.prealbumin bound/Prealbumin [Mass ratio]
Consumer Name Alpha Get Info
T4.prealbumin bound/Prealbumin, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0k
Last Updated
Version 2.73
Order vs. Observation
Observation
Common Test Rank Get Info
15273

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) tiroxina.fijada a prealbúmina/prealbúmina:relación de concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ES Spanish (Spain) Prealbumina fijadora de tiroxina/Prealbumina:Relacion de Masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Tiroxina, prealbúmina unida / Prealbúmina:Relación de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE Estonian (Estonia) Türoksiin.prealbumiiniga seotud/prealbumiin:MRto:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-FR French (France) Thyroxine liée à la préalbumine/préalbumine:Masse ratio:Ponctuel:Sérum/Plasma:Numérique:
it-IT Italian (Italy) Tiroxina.legata alla prealbumina/Prealbumina:MRto:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Plasma Punto nel tempo (episodio) Rapporto di Massa Siero Siero o Plasma
ko-KR Korean (Korea, Republic Of) 프리알부민 결합 티록신/프리알부민:질량농도비:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) thyroxine.prealbumine-gebonden/pre-albumine:massaverhouding:moment:serum of plasma:kwantitatief:
pl-PL Polish (Poland) Tyroksyna, związana z prealbuminą/prealbumina:współczynnik masowy:punkt w czasie:surowica lub osocze:ilościowy:
pt-BR Portuguese (Brazil) Tiroxina.ligada a prealbumina/Prealbumina:MCrto:Pt:Sor/Plas:Qn:
Synonyms: ; T4 PA Bnd; TBPA; T-4; Thyrox; Thyrx; Thyroxin; Levothyroxine; Levo-thyroxine; L-thyroxine; Prealb; Pre albumin; Transthyretin; T4 PA Bnd/Prealb; mRto; Mass concentration ratio; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Chemistry
ru-RU Russian (Russian Federation) Тироксин.преальбумин связанный/Преальбумин:МассОтн:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Масс отношение Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Tiroksin.prealbumine bağlı/Prealbumin:KütlOr:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 甲状腺素.前白蛋白结合型/前白蛋白:质量比率:时间点:血清/血浆:定量型:
Synonyms: Prealb;TTR;前清蛋白;甲状腺素蛋白;甲状腺素运载蛋白;视黄醇/甲状腺素运载蛋白;转甲状腺素蛋白;转甲状腺素蛋白（transthyretin，TTR，一种异常结构的前清蛋白）;转甲状腺蛋白;转甲蛋白;转甲视蛋白;运甲状腺素蛋白 T4 PA Bnd;T4.前白蛋白结合型;TBPA;前白蛋白结合型 T4;前白蛋白结合型甲状腺素 T4;T-4;四碘甲状腺原氨酸;四碘甲腺原氨酸;左旋四碘甲状腺原氨酸;左旋四碘甲腺原氨酸;左旋甲状腺氨酸;左旋甲状腺素;左旋甲状腺素（Levothyroxine，Levo-thyroxine，L-thyroxine）;甲状腺氨酸 前清蛋白 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 来自于同一体系的两种分析物的质量之比;质量比 血清或血浆

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CodeSystem lookup
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