14190-3
Phenytoin Free [Mass/volume] in Saliva (oral fluid)
Active
Part Descriptions
LP14731-1 Phenytoin.free
Phenytoin-free levels detect the level of non-protein-bound phenytoin in the blood. It is used to measure therapeutic and toxic levels of the drug.
Source: Regenstrief Institute
LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583
Source: Regenstrief LOINC
LP207910-3 free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity.
Source: Regenstrief LOINC
LP262420-5 Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Phenytoin.free:
MCnc: Pt: Saliva: Qn: - Long Common Name
- Phenytoin Free [Mass/volume] in Saliva (oral fluid)
- Short Name
- Phenytoin Free Sal-mCnc
- Display Name
- Phenytoin Free (Sal) [Mass/Vol]
- Consumer Name Alpha Get Info
- Free phenytoin, Saliva
Part Model Get Info
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0k
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 5174
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Fenytoin volný: |
| el-GR | Greek (Greece) | Φαινυτοΐνη.ελεύθερη: Synonyms: DRUG/TOX MCnc Pt Qn Σίελος Φαινυτοΐνη Φαινυτοΐνη.ελεύθερη |
| es-AR | Spanish (Argentina) | fenitoína.libre: |
| es-ES | Spanish (Spain) | Fenitoína libre: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Phenytoin.libre: |
| et-EE | Estonian (Estonia) | Fenütoiin.vaba: Synonyms: Juhuslik Kvantitatiivne Sülg |
| fr-CA | French (Canada) | Phénytoïne.libre: |
| fr-FR | French (France) | Diphénylhydantoïne libre: |
| fr-BE | French (Belgium) | Phénytoïne.libre: |
| it-IT | Italian (Italy) | Fenitoina.libera: Synonyms: Concentrazione di Massa Fenitoina Libera Livelli farmacologici e tossicologia Punto nel tempo (episodio) |
| ko-KR | Korean (Korea, Republic Of) | 유리페니토인: |
| nl-NL | Dutch (Netherlands) | fenytoïne.vrij: |
| pt-BR | Portuguese (Brazil) | Fenitoína.livre: Synonyms: Diphenylhydantoin; |
| ru-RU | Russian (Russian Federation) | Фенитоин.свободный: Synonyms: Количественный Массовая концентрация Точка во времени; |
| tr-TR | Turkish (Turkey) | Fenitoin.serb: |
| zh-CN | Chinese (China) | 苯妥英.游离型: Synonyms: C15H12N2O2; |
Example Units
| Unit | Source |
|---|---|
| mg/L | Example UCUM Units |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://