Log In

Part Description

LP16719-4   Jo-1 extractable nuclear
Aminoacyl-tRNA synthetases (ARS) are enzymes that link amino acids to tRNA molecules and therefore play a key role in protein synthesis. Each ARS is specific for a single amino acid. [NCBI Books: NBK22356] Autoantibodies to ARS are a hallmark of connective tissue diseases including anti-synthetase syndrome (ASS) and idiopathic inflammatory myopathies such as polymyositis (PM) and dermatomyositis (DM). ASS, PM and DM have overlapping features, including myositis, arthralgia, skin manifestations and interstitial lung disease. Antibodies to several specific ARS enzymes have been identified, including anti-histidyl (anti-Jo-1), anti-threonyl (anti-PL-7), anti-alanyl (anti-PL-12), anti-glycyl (anti-Ej), anti-isoleucyl (anti-Oj), anti-asparaginyl (anti-Ks), anti-phenylalanyl (anti-Zo), and anti-tyrosyl (anti-Ha). Different antibodies or patterns of antibodies have been associated with specific clinical features. Anti-Jo-1, anti-Ej, and anti-PL-7 antibodies are associated with myositis, including classic DM, clinically amyopathic DM (CADM) and PM. Anti-PL-12 alone is associated with CADM or interstitial lung disease (ILD). Anti-Ej and anti-PL-12 together are associated with CADM. Anti-Ks and anti-Oj are associated with ILD alone. PMID: 23573256 Anti-Ha and anti-Zo antibodies are the most recent autoantibodies to be identified in patients with symptoms of ASS. PMID: 17392287 Identifying the particular anti-ARS antibodies associated with an individual patient's disease may help guide treatment and predict clinical outcomes. Source: Regenstrief LOINC, PMID: 23573256

LOINC Names Get Info

Fully-Specified Name
Jo-1 extractable nuclear Ab:Titr:Pt:Ser:SemiQn:
Long Common Name
Jo-1 extractable nuclear Ab [Titer] in Serum
Short Name
ENA Jo1 Ab Titr Ser
Display Name
Jo-1 extractable nuclear Ab (S) [Titer]
Consumer Name Alpha Get Info
Jo-1 extractable nuclear antibody, Blood

Part Model Get Info

  • Component
    Jo-1 extractable nuclear Ab
    LP38741-2
    • Analyte
      Jo-1 extractable nuclear Ab
      LP38741-2
      • Component Numerator
        Jo-1 extractable nuclear Ab
        LP38741-2
        • Component Numerator Core
          Jo-1 extractable nuclear
          LP16719-4
        • Component Numerator Core Suffix
          Ab
          LP20667-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Titr
    LP6881-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    SemiQn
    LP436123-6
  • Method
    NULL
     

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 1.0k
Last Updated
Version 2.75 (MAJ)
Order vs. Observation
Both
Common Test Rank Get Info
6615

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Antinukleární protilátky Jo-1 extrahovatelné:Arbitrární koncentrace (titr):Časový bod:Sérum:Semikvantitativní:
de-DEGerman (Germany)Jo-1 extrahierbarer nukleärer Ak:Titer:Zeitpunkt:Serum:Semiquantitativ:
Synonyms: Jo-1
de-ATGerman (Austria)Synonyms: Jo-1-Ti.IF
el-GRGreek (Greece)εκχυλίσιμα πυρηνικά αντιγόνα Jo-1 Αντίσωμα:Titr:Pt:Ορός:Ημιποσοτική:
Synonyms: Pt SERO Titr Αντίσωμα Εκχυλίσιμα πυρηνικά εκχυλίσιμα πυρηνικά αντιγόνα Jo-1 Ημιποσοτική Ορός Πυρηνικό
es-ARSpanish (Argentina)[anticuerpo] antinuclear extraíble JO-1 [Ac]:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:
es-ESSpanish (Spain)Jo-1 Anticuerpos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:
Synonyms: Semicuantitativo
es-MXSpanish (Mexico)Ab nuclear extraíble Jo-1:Título:Punto temporal:Suero:Cuantitativo:
fr-CAFrench (Canada)Jo-1 nucléaire soluble, Ac:Titre:Temps ponctuel:Sérum:SemiQn:
fr-FRFrench (France)Jo-1 Ac:Titre:Ponctuel:Sérum:Semi-Quantitatif:
it-ITItalian (Italy)Jo-1, nucleare estraibile Ab:Titr:Pt:Siero:SemiQn:
Synonyms: anticorpo ENA Jo1 Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant Titolo
ko-KRKorean (Korea, Republic Of)Jo-1 추출성 핵 항체:역가:검사시점:혈청:정량:
nl-NLDutch (Netherlands)jo-1 extraheerbaar nucleair As:titer:moment:serum:semikwantitatief:
Synonyms: antistof; antilichaam
pl-PLPolish (Poland)Jo-1 rozpuszczalny jądrowy Ab:miano:punkt w czasie:surowica:półilościowy:
Synonyms: Jo-1 rozpuszczalny jądrowy Przeciwciała do rozpuszczalnego antygenu jądrowego Przeciwciała do rozpuszczalnego jądrowego antygenu Jo-1 Przeciwciała przeciwjądrowe
pt-BRPortuguese (Brazil)Jo-1 Ac:Título:Pt:Soro:Qn:
Synonyms: ; ANA; ANF; NA; Antinuclear antibody; Nuc; ENA Jo1; Histidyl-tRNA synthease; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; I; Serology
zh-CNChinese (China)Jo-1 可提取性核 抗体:滴定度:时间点:血清:半定量型:
Synonyms: Ⅰ Ab;自身抗体 ANA ENA Ab ENA Jo1 Ab ENA Jo-1 Ab ENA Jo1 抗体 ENA Jo-1 抗体 ENA Jo1;ENA Jo-1;Jo-1 可提取性核 Ag;Jo-1 可提取性核抗原;可提取性核 Ag Jo1;可提取性核 Ag Jo-1;可提取性核抗原 Jo1;可提取性核抗原 Jo-1;组氨酰-tRNA 合成酶;组氨酰基-tRNA 合成酶 ENA 抗体 ENA;可提取性核 Ag;可提取性核抗原;可提取性核抗原（Extractable Nuclear Antigen，ENA）;可提取性细胞核;可提取性细胞核 Ag;可提取性细胞核抗原;盐水可提取性核 Ag;盐水可提取性核抗原;盐水可提取性细胞核 Ag;盐水可提取性细胞核抗原 I Jo1 可提取性核 Ab Jo-1 可提取性核 Ab Jo1 可提取性核 Ag Ab Jo-1 可提取性核 Ag Ab Jo1 可提取性核抗体 Jo1 可提取性核抗原 抗体 Jo-1 可提取性核抗原 抗体 NA 可提取性核 Ab 可提取性核 Ag Jo1 Ab 可提取性核 Ag Jo-1 Ab 可提取性核 Ag 之 Ab 可提取性核抗原 Jo1 抗体 可提取性核抗原 Jo-1 抗体 可提取性核抗原之抗体 抗 ENA 抗可提取性核 Ag 抗可提取性核抗原 抗核 Ab 抗核抗体 抗核抗体（Antinuclear antibody，ANA） 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 核;胞核 细胞核 Ab 胞核 Ab 胞核抗体 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

UnitSource
{titer}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=14235-6