14656-3
cloZAPine [Moles/volume] in Serum or Plasma
Active
Part Descriptions
LP17236-8 cloZAPine
Clozapine (sold as Clozaril ®, Leponex ®, Fazaclo ®) was the first of the atypical antipsychotics to be developed. It was approved by the United States Food and Drug Administration (FDA) in 1989 and is the only FDA-approved medication indicated for treatment-resistant schizophrenia and for reducing the risk of suicidal behaviour in patients with schizophrenia.
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Source: Wikipedia, Clozapine (Wikipedia)
LP17236-8 cloZAPine
A tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Agranulocytosis is a major adverse effect associated with administration of this agent.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- cloZAPine
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- cloZAPine SerPl-sCnc
- Display Name
- cloZAPine [Moles/Vol]
- Consumer Name Alpha Get Info
- cloZAPine, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0k
- Last Updated
- Version 2.34
- Order vs. Observation
- Both
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG48379-8 | Clozapine| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Clozapin: |
es-AR | Spanish (Argentina) | clozapina: |
es-ES | Spanish (Spain) | Clozapina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | clozapina: |
et-EE | Estonian (Estonia) | Klosapiin: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
fr-CA | French (Canada) | Clozapine: Synonyms: #REF! |
fr-FR | French (France) | Clozapine: |
fr-BE | French (Belgium) | Clozapine: |
it-IT | Italian (Italy) | Clozapina: Synonyms: Concentrazione di Sostanza Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
ko-KR | Korean (Korea, Republic Of) | 클로자핀: |
nl-NL | Dutch (Netherlands) | clozapine: |
pt-BR | Portuguese (Brazil) | Clozapina: Synonyms: Clozaril; |
ru-RU | Russian (Russian Federation) | Клозапин: Synonyms: Количественный Молярность; |
tr-TR | Turkish (Turkey) | Klozapine: |
zh-CN | Chinese (China) | 氯氮平: Synonyms: 克分子浓度; |
Example Units
Unit | Source |
---|---|
nmol/L | Example UCUM Units |
nmol/L | eCHN |
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