14671-2

Coproporphyrin 3 [Moles/volume] in Serum or Plasma

Active

Part Description

LP14372-4 Coproporphyrin 3
Coproporhyrin III is a porphyrin metabolite arising from heme synthesis. Porphyrins are pigments found in both animal and plant life. Coproporphyrin III is a tetrapyrrole dead-end product from the spontaneous oxidation of the methylene bridges of coproporphynogen, arising from heme synthesis and secreted in feces and urine. Increased levels of coproporphyrins can indicate congenital erythropoietic porphyria or sideroblastic anaemia. Porphyria is a pathological state characterised by abnormalities of porphyrin metabolism and results in the excretion of large quantities of porphyrins in the urine and in extreme sensitivity to light. A large number of factors are capable of increasing porphyrin excretion, owing to different and multiple causes and etiologies: 1) the main site of the chronic hepatic porphyria disease process concentrates on the liver, 2) a functional and morphologic liver injury is almost regularly associated with this chronic porphyria, 3) the toxic form due to occupational and environmental exposure takes mainly a subclinical course. Hepatic factors includes disturbance in coproporphyrinogen metabolism, which results from inhibition of coproporphyrinogen oxidase as well as from the rapid loss from, and diminished utilization of coproporphyrinogen in the hepatocytes, which may also explain why coproporphyrin, its autoxidation product, predominates physiologically in the urine; decreased biliary excretion of coproporphyrin leading to a compensatory urinary excretion, so that the coproporphyrin ring isomer ratio (1:III) becomes a sensitive index for impaired liver function and intrahepatic cholestasis; and disturbed activity of hepatic uroporphyrinogen decarboxylase. In itself, secondary coproporphyrinuria is not associated with porphyria symptoms of a hepatologic-gastroenterologic, neurologic, or dermatologic order, even though coproporphyrinuria can occur with such symptoms. PMID: 3327428 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Corproporphyrin III

LOINC Names Get Info

Fully-Specified Name: Coproporphyrin 3:SCnc:Pt:Ser/Plas:Qn:
Long Common Name: Coproporphyrin 3 [Moles/volume] in Serum or Plasma
Short Name: Copro3 SerPl-sCnc
Display Name: Coproporphyrin 3 [Moles/Vol]
Consumer Name Alpha Get Info: Coproporphyrin 3, Blood

Part Model Get Info

Component
Coproporphyrin 3
LP14372-4
- Analyte
  Coproporphyrin 3
  LP14372-4
  - Component Numerator
    Coproporphyrin 3
    LP14372-4
    - Component Numerator Core
      Coproporphyrin 3
      LP14372-4
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
SCnc
LP6860-3
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 1.0k
Last Updated: Version 2.34 (MIN)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
77009-9	Porphyrin fractions panel [Moles/volume] - Serum or Plasma

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Koproporfyrin 3:Látková koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
de-DE	German (Germany)	Coproporphyrin 3:Stoffmengenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:
el-GR	Greek (Greece)	Κοπροπορφυρίνη 3:SCnc:Pt:Ορός/Πλάσμα:Qn: Synonyms: CHEM Pt Qn SCnc Κοπροπορφυρίνη Κοπροπορφυρίνη 3 Ορός Ορός/Πλάσμα Πλάσμα
es-AR	Spanish (Argentina)	coproporfirina 3:concentración de sustancia:punto en el tiempo:plasma:cuantitativo:
es-ES	Spanish (Spain)	Coproporfirina 3:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Coproporfirina 3:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE	Estonian (Estonia)	Koproporfüriin 3:SCnc:Pt:S/P:Qn: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA	French (Canada)	Coproporphyrine 3:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR	French (France)	Coproporphyrine 3:Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE	French (Belgium)	Coproporphyrine 3:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT	Italian (Italy)	Coproporfirina 3:SCnc:Pt:Siero/Plasma:Qn: Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR	Korean (Korea, Republic Of)	코프로포르피린 3:물질농도:검사시점:혈청/혈장:정량:
nl-NL	Dutch (Netherlands)	coproporfyrine 3:mol/volume:moment:serum of plasma:kwantitatief:
pt-BR	Portuguese (Brazil)	Coproporfirina 3:SCnc:Pt:Sor/Plas:Qn: Synonyms: ; Copro3; Coproporphyrin III; Coproporphyrins; Copro; Tetracarboxyporphyrin; Coproporph; Tetracarboxyl porphyrin; Tetracarboxylporphyrin; Tetracarboxylporphyrins; Substance concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Chemistry
ru-RU	Russian (Russian Federation)	Копропорфирин 3:МолКонц:ТчкВрм:Сыв/Плаз:Колич: Synonyms: Количественный Молярность;Молярная объёмная концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Koproporfirin 3:SubKons:Zmlı:Ser/Plaz:Kant:
zh-CN	Chinese (China)	粪卟啉 III:物质的量浓度:时间点:血清/血浆:定量型: Synonyms: Ⅲ Copro;Coproporph;四羧基卟啉 Copro3;粪卟啉 3;粪卟啉Ⅲ III 三克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类叁可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间血清或血浆

Example Units

Unit	Source
nmol/L	Example UCUM Units
nmol/L	eCHN

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.