14978-1

cycloSPORINE [Mass/volume] in Blood by Immunoassay

Active

Part Description

LP16098-3 cycloSPORINE
Cyclosporine (Brand names Neoral, Restasis, Sandimmune, Gengraf) is a cyclic undecapeptide of fungal origin and a potent calcineurin inhibitor immunosuppressive agent. The introduction of cyclosporine in human organ transplantation substantially improved patient and graft survival in patients receiving heart, kidney, liver, pancreas, lung or bone marrow transplants. Cyclosporine was the first drug to specifically and reversibly inhibit the activation and proliferation of lymphocytes. The main mechanism through which cyclosporine exerts its immunosuppressive effect is the inhibition of T cell activation and proliferation. Monitoring and concentration-controlled dosing is required to maintain patient drug levels within a narrow therapeutic window; low levels could cause transplant rejection and high levels may cause nephrotoxicity. PMID: 19545653 Source: Regenstrief LOINC, PMID: 19545653

LOINC Names Get Info

Fully-Specified Name: cycloSPORINE:MCnc:Pt:Bld:Qn:IA
Long Common Name: cycloSPORINE [Mass/volume] in Blood by Immunoassay
Short Name: cycloSPORINE Bld IA-mCnc
Display Name: cycloSPORINE IA (Bld) [Mass/Vol]
Consumer Name Alpha Get Info: cycloSPORINE, Blood

Part Model Get Info

Component
cycloSPORINE
LP16098-3
- Analyte
  cycloSPORINE
  LP16098-3
  - Component Numerator
    cycloSPORINE
    LP16098-3
    - Component Numerator Core
      cycloSPORINE
      LP16098-3
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld
LP7057-5
- System Core
  Bld
  LP7057-5
- Super System
  NULL
Scale
Qn
LP7753-9
Method
IA
LP217197-5

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 1.0k
Last Updated: Version 2.73 (MIN)
Change Reason: The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 5401

Member of these Groups Get Info

LOINC Group	Group Name
LG3077-7	Cyclosporine\|MCnc\|Pt\|ANYBldSerPl
LG43291-0	Cyclosporine\|Pt\|Bld\|IA

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Cyklosporin:Hmotnostní koncentrace:Časový bod:Krev:Kvantitativní:Imunoanalýza
de-DE	German (Germany)	Cyclosporin:Massenkonzentration:Zeitpunkt:Blut:Quantitativ:Immunoassay Synonyms: Ciclosporin
el-GR	Greek (Greece)	Κυκλοσπορίνη:MCnc:Pt:Αίμα:Qn:IA Synonyms: DRUG/TOX IA MCnc Pt Qn Αίμα Κυκλοσπορίνη
es-AR	Spanish (Argentina)	ciclosporina:concentración de masa:punto en el tiempo:sangre:cuantitativo:enzimoinmunoanálisis
es-ES	Spanish (Spain)	Ciclosporina:Concentración de masa:Punto temporal:Sangre:Qn:IA Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	cicloesporino:Concentración de masa:Punto temporal:Sangre:Cuantitativo:Inmunoensayo
et-EE	Estonian (Estonia)	Tsüklosporiin:MCnc:Pt:B:Qn:IA Synonyms: Juhuslik Kvantitatiivne Veri
fr-CA	French (Canada)	Cyclosporine:Concentration de masse:Temps ponctuel:Sang:Quantitatif:IA
fr-FR	French (France)	Ciclosporine:Masse/Volume:Ponctuel:Sang:Numérique:Immunoanalyse
fr-BE	French (Belgium)	Cyclosporine:Concentration de masse:Temps ponctuel:Sang:Quantitatif:IA
it-IT	Italian (Italy)	Ciclosporina:MCnc:Pt:Sangue:Qn:IA Synonyms: Concentrazione di Massa Immunoassay Livelli farmacologici e tossicologia Punto nel tempo (episodio) Sangue
ko-KR	Korean (Korea, Republic Of)	시클로스포린:질량농도:검사시점:전혈:정량:효소면역측정법
nl-NL	Dutch (Netherlands)	ciclosporine:massa/volume:moment:bloed:kwantitatief:immunoassay Synonyms: IA
pl-PL	Polish (Poland)	Cyklosporyna:stężenie masowe:punkt w czasie:krew:ilościowy:metoda immunologiczna
pt-BR	Portuguese (Brazil)	Ciclosporina:MCnc:Pt:SgTotal:Qn:Imunoensaio Synonyms: ; Cyclosporin; Cyclosporins; CsA; Ciclosporin; Ciclosporine; Neoral; SangCya; Cyclosporin a; Sandimmune; Mass concentration; Level; Point in time; Random; Blood; WB; Whole blood; Quantitative; QNT; Quant; Quan; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU	Russian (Russian Federation)	Циклоспорин:МассКонц:ТчкВрм:Кр:Колич:IA Synonyms: Количественный Кровь Массовая концентрация Точка во времени;Момент
tr-TR	Turkish (Turkey)	Siklosporin:KütlKons:Zmlı:Kan:Kant:İA Synonyms: İmmünölçüm, immünoassay
zh-CN	Chinese (China)	环孢菌素:质量浓度:时间点:全血:定量型:免疫测定法 Synonyms: 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间毒品毒品类水平;浓度;质量浓度(单位体积) 环孢霉素A; 山地明环孢灵; 环孢多肽A; 环孢素; 赛斯平; 环孢菌素; 环孢菌素A; 环孢素A;山地明;环孢多肽;环孢抑制剂;环孢灵;环孢霉素;环孢霉素A;环孢素;Cyclosporine;Cyclosporin; Restasis; Cyclosporine A; cyclosporin A; Antibiotic S 7481F1; 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonameth 药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类血;血液

Example Units

Unit	Source
ug/L	Example UCUM Units
ug/L	eCHN

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.