14978-1
cycloSPORINE [Mass/volume] in Blood by Immunoassay
Active
Part Description
LP16098-3 cycloSPORINE
Cyclosporine (Brand names Neoral, Restasis, Sandimmune, Gengraf) is a cyclic undecapeptide of fungal origin and a potent calcineurin inhibitor immunosuppressive agent. The introduction of cyclosporine in human organ transplantation substantially improved patient and graft survival in patients receiving heart, kidney, liver, pancreas, lung or bone marrow transplants. Cyclosporine was the first drug to specifically and reversibly inhibit the activation and proliferation of lymphocytes. The main mechanism through which cyclosporine exerts its immunosuppressive effect is the inhibition of T cell activation and proliferation. Monitoring and concentration-controlled dosing is required to maintain patient drug levels within a narrow therapeutic window; low levels could cause transplant rejection and high levels may cause nephrotoxicity. PMID: 19545653
Source: Regenstrief LOINC, PMID: 19545653
Fully-Specified Name
- Component
- cycloSPORINE
- Property
- MCnc
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
- IA
Additional Names
- Long Common Name
- cycloSPORINE [Mass/volume] in Blood by Immunoassay
- Short Name
- cycloSPORINE Bld IA-mCnc
- Display Name
- cycloSPORINE IA (Bld) [Mass/Vol]
- Consumer Name Alpha Get Info
- cycloSPORINE, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0k
- Last Updated
- Version 2.73
- Change Reason
- The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 5401
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG3077-7 | Cyclosporine| |
| LG43291-0 | Cyclosporine| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Cyclosporin: Synonyms: Ciclosporin |
| el-GR | Greek (Greece) | Κυκλοσπορίνη: |
| es-AR | Spanish (Argentina) | ciclosporina: |
| es-ES | Spanish (Spain) | Ciclosporina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | cicloesporino: |
| et-EE | Estonian (Estonia) | Tsüklosporiin: Synonyms: Juhuslik Kvantitatiivne Veri |
| fr-CA | French (Canada) | Cyclosporine: |
| fr-FR | French (France) | Ciclosporine: |
| fr-BE | French (Belgium) | Cyclosporine: |
| it-IT | Italian (Italy) | Ciclosporina: Synonyms: Concentrazione di Massa Immunoassay Livelli farmacologici e tossicologia Punto nel tempo (episodio) Sangue |
| ko-KR | Korean (Korea, Republic Of) | 시클로스포린: |
| nl-NL | Dutch (Netherlands) | ciclosporine: Synonyms: IA |
| pt-BR | Portuguese (Brazil) | Ciclosporina: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Циклоспорин: Synonyms: Количественный Кровь Массовая концентрация Точка во времени; |
| tr-TR | Turkish (Turkey) | Siklosporin: Synonyms: İmmünölçüm, immünoassay |
| zh-CN | Chinese (China) | 环孢菌素: Synonyms: 免疫测定; |
Example Units
| Unit | Source |
|---|---|
| ug/L | Example UCUM Units |
| ug/L | eCHN |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=14978-1
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://