16717-1

Cytomegalovirus Ag [Presence] in Urine by Immunoassay

Active

Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Fully-Specified Name

Component

Cytomegalovirus Ag

Property

PrThr

Time

Pt

System

Urine

Scale

Ord

Method

IA

Additional Names

Short Name

CMV Ag Ur Ql IA

Display Name

CMV Ag IA Ql (U)

Consumer Name Alpha Get Info

Cytomegalovirus (CMV) antigen, Urine

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 1.0l

Last Updated

Version 2.56

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Member of these Groups Get Info

Language Variants Get Info

Related Names

• Antigen
• Antigens
• CMV
• Cytomegalo virus
• Cytomgal
• EIA
• ELFA
• ELISA
• Enzyme immunoassay
• HHV-5
• Human Herpesvirus-5
• IAA
• ID
• Infectious Disease
• InfectiousDisease
• MEIA
• Microbiology
• Ordinal
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Screen
• SUDS
• UA
• UR
• Urn

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CodeSystem lookup

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LOINC Copyright

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.