Version 2.77

Part Description

LP16719-4   Jo-1 extractable nuclear
Aminoacyl-tRNA synthetases (ARS) are enzymes that link amino acids to tRNA molecules and therefore play a key role in protein synthesis. Each ARS is specific for a single amino acid. [NCBI Books: NBK22356] Autoantibodies to ARS are a hallmark of connective tissue diseases including anti-synthetase syndrome (ASS) and idiopathic inflammatory myopathies such as polymyositis (PM) and dermatomyositis (DM). ASS, PM and DM have overlapping features, including myositis, arthralgia, skin manifestations and interstitial lung disease. Antibodies to several specific ARS enzymes have been identified, including anti-histidyl (anti-Jo-1), anti-threonyl (anti-PL-7), anti-alanyl (anti-PL-12), anti-glycyl (anti-Ej), anti-isoleucyl (anti-Oj), anti-asparaginyl (anti-Ks), anti-phenylalanyl (anti-Zo), and anti-tyrosyl (anti-Ha). Different antibodies or patterns of antibodies have been associated with specific clinical features. Anti-Jo-1, anti-Ej, and anti-PL-7 antibodies are associated with myositis, including classic DM, clinically amyopathic DM (CADM) and PM. Anti-PL-12 alone is associated with CADM or interstitial lung disease (ILD). Anti-Ej and anti-PL-12 together are associated with CADM. Anti-Ks and anti-Oj are associated with ILD alone. PMID: 23573256 Anti-Ha and anti-Zo antibodies are the most recent autoantibodies to be identified in patients with symptoms of ASS. PMID: 17392287 Identifying the particular anti-ARS antibodies associated with an individual patient's disease may help guide treatment and predict clinical outcomes. Source: Regenstrief LOINC, PMID: 23573256

Fully-Specified Name

Component
Jo-1 extractable nuclear Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IF

Additional Names

Short Name
ENA Jo1 Ab Ser Ql IF
Display Name
Jo-1 extractable nuclear Ab IF Ql (S)
Consumer Name Alpha Get Info
Jo-1 extractable nuclear antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 1.0l
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG5369-6 Jo-1 extractable nuclear Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Jo-1 extrahierbarer nukleärer Ak:Nachweis oder Schwellenwert:Zeitpunkt:Serum:Ordinal:Immunfluoreszenztest
Synonyms: Jo-1
es-AR Spanish (Argentina) [anticuerpo] antinuclear extraíble JO-1 [Ac]:concentración arbitraria:punto en el tiempo:suero:ordinal:inmunofluorescencia
es-ES Spanish (Spain) Jo-1 Anticuerpos:PrThr:Punto temporal:Suero:Ord:Inmunofluorescencia (IF)
es-MX Spanish (Mexico) Ab nuclear extraíble Jo-1:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunofluorescencia (IF)
fr-CA French (Canada) Jo-1 nucléaire soluble , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunofluorescence
fr-FR French (France) Jo-1 anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunofluorescence
fr-BE French (Belgium) Jo-1 nucléaire soluble Ac:PrThr:Temps ponctuel:Sérum:Ordinal:Immunofluorescence
Synonyms: Anticorps
it-IT Italian (Italy) Jo-1, nucleare estraibile Ab:PrThr:Pt:Siero:Ord:IF
Synonyms: anticorpo ENA Immunofluorescenza (IF) Jo1 Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
ko-KR Korean (Korea, Republic Of) Jo-1 추출성 핵 항체:임의농도:검사시점:혈청:순위척도:면역형광
nl-NL Dutch (Netherlands) jo-1 extraheerbaar nucleair As:aanwezigheid:moment:serum:ordinaal:immunofluorescentie
Synonyms: antistof; antilichaam IF
pl-PL Polish (Poland) Jo-1 rozpuszczalny jądrowy Ab:granica wykrywalności:punkt w czasie:surowica:półilościowy:immunofluorescencja
Synonyms: Jo-1 rozpuszczalny jądrowy Przeciwciała do rozpuszczalnego antygenu jądrowego Przeciwciała do rozpuszczalnego jądrowego antygenu Jo-1 Przeciwciała przeciwjądrowe
pt-BR Portuguese (Brazil) Jo-1 Ac:ACnc:Pt:Soro:Ord:Imunofluorescência
Synonyms: ; ANA; ANF; NA; Antinuclear antibody; Nuc; ENA Jo1; Histidyl-tRNA synthease; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; ACIF; FA; Fluorescent antibody; Immune fluorescence; Fluoresent; Immunoflour; Immunofluor; Immunofluorescence; IFA; Time Resolved Fluorescence; Anticomplement Immunofluorescence; TRF; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; I; Serology; FANA
ru-RU Russian (Russian Federation) Jo-1 экстрагируемый ядерный Ат:PrThr:ТчкВрм:Сыв:Пор:ИФ
Synonyms: Антитело Иммунофлюоресценция (ИФ) Порядковый Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Jo-1 öztlenebilir çekirdek Ab:MevcEşik:Zmlı:Ser:Srl:IF
Synonyms: Ak Çekirdek İmmünflorerans Mevcut
zh-CN Chinese (China) Jo-1 可提取性核 抗体:存在情况或阈值:时间点:血清:序数型:免疫荧光法
Synonyms: Ⅰ Ab;自身抗体 ANA ENA Ab ENA Jo1 Ab ENA Jo-1 Ab ENA Jo1 抗体 ENA Jo-1 抗体 ENA Jo1;ENA Jo-1;Jo-1 可提取性核 Ag;Jo-1 可提取性核抗原;可提取性核 Ag Jo1;可提取性核 Ag Jo-1;可提取性核抗原 Jo1;可提取性核抗原 Jo-1;组氨酰-tRNA 合成酶;组氨酰基-tRNA 合成酶 ENA 抗体 ENA;可提取性核 Ag;可提取性核抗原;可提取性核抗原（Extractable Nuclear Antigen，ENA）;可提取性细胞核;可提取性细胞核 Ag;可提取性细胞核抗原;盐水可提取性核 Ag;盐水可提取性核抗原;盐水可提取性细胞核 Ag;盐水可提取性细胞核抗原 FANA I IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 Jo1 可提取性核 Ab Jo-1 可提取性核 Ab Jo1 可提取性核 Ag Ab Jo-1 可提取性核 Ag Ab Jo1 可提取性核抗体 Jo1 可提取性核抗原 抗体 Jo-1 可提取性核抗原 抗体 NA 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 可提取性核 Ab 可提取性核 Ag Jo1 Ab 可提取性核 Ag Jo-1 Ab 可提取性核 Ag 之 Ab 可提取性核抗原 Jo1 抗体 可提取性核抗原 Jo-1 抗体 可提取性核抗原之抗体 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 抗 ENA 抗可提取性核 Ag 抗可提取性核抗原 抗核 Ab 抗核抗体 抗核抗体（Antinuclear antibody，ANA） 时刻;随机;随意;瞬间 核;胞核 核心抗原抗体免疫荧光 细胞核 Ab 胞核 Ab 胞核抗体 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=17031-6