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Part Descriptions

LP14377-3   Aldosterone
Aldosterone is a steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland to regulate sodium and potassium balance in the blood. It is synthesized from cholesterol by aldosterone synthase, which is absent in other sections of the adrenal gland. It is the sole endogenous member of the class of mineralocorticoids. Acting on mineralocorticoid receptors (MR) on principal cells in the collecting ducts of the kidneys, it increases the permeability of their apical (luminal) membrane to potassium and sodium and activates their basolateral Na+K+ pumps, stimulating ATP hydrolysis, reabsorbing sodium (Na+) ions and water into the blood, and excreting potassium (K+) ions into the urine. Aldosterone also stimulates H+ secretion by intercalated cells in the collecting duct, regulating plasma bicarbonate (HCO3-) levels and its acidbase balance. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Aldosterone (Wikipedia)

LP14377-3   Aldosterone
Used to detect hyper and hypo aldosteronisnm. Hypoaldosteronism can occur in any condition that causes destruction or dysfunction of the adrenal gland.1,2,4 Hypoaldosterism can be due to primary adrenal insufficiency , congenital adrenal hypoplasia, acquired secondary aldosterone deficiency (hyporeninemic hypoaldosteronism), and acquired Hyporeninemic hypoaldosteronism is the most common form of isolated hypoaldosteronism and is results from impaired renin release from the kidney. Congenital hypoaldosteronism caused by inherited enzymatic defects in aldosterone biosynthesis are rare. Corticosterone methyloxidase I (CMO I) deficiency is associated with elevated serum levels of corticosterone and low levels of 18-hydroxy-corticosterone and aldosterone. Corticosterone methyloxidase II (CMO II) deficiency produces high levels of 18-hydroxy-corticosterone, the immediate precursor of aldosterone.
Acquired primary hypoaldosteronism can be caused by the administration of heparin. Also, persistently hypotensive, critically ill patients with sepsis, pneumonia, peritonitis, cholangitis, and liver failure can have inappropriately low plasma aldosterone concentrations in relation to elevated plasma renin activity. Primary hyperaldosteronism, also referred to as Conn syndrome, is due to overproduction of aldosterone by one or both of the adrenal glands. Some recent studies suggest that 10% to 15% of Hyper thyroidism cases are due to (or associated with ) primary hyperaldosteronism. Secondary hyperaldosteronism is relatively common and can occur as the result of any condition that decreases blood flow to the kidneys (ie, renal artery stenosis), decreases blood pressure, or lowers plasma sodium levels. Secondary hyperaldosteronism may also be seen with cirrhosis, congestive heart failure. and toxemia of pregnancy. Several studies have suggested that high-normal aldosterone levels predict development of high blood pressure in normotensive subjects and that increased aldosterone action contributes to hypertension, cardiovascular fibrosis, and cardiac hypertrophy. Source: Regenstrief Institute

LOINC Names Get Info

Fully-Specified Name
Aldosterone renal clearance:VRat:24H:Urine+Ser/Plas:Qn:
Long Common Name
Aldosterone renal clearance in 24 hour Urine and Serum or Plasma
Short Name
Aldost Cl 24h Ur+SerPl-vRate
Display Name
Aldosterone renal clearance (24H U+S/P) [Vol/Time]
Consumer Name Alpha Get Info
Aldosterone renal clearance, Urine+Blood

Part Model Get Info

  • Component
    Aldosterone renal clearance
    LP173999-6
    • Analyte
      Aldosterone renal clearance
      LP173999-6
      • Component Numerator
        Aldosterone renal clearance
        LP173999-6
        • Component Numerator Core
          Aldosterone
          LP14377-3
        • Component Numerator Core Suffix
          renal clearance
          LP33137-8
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    VRat
    LP6895-9
  • Time
    24H
    LP6924-7
  • System
    Urine+Ser/Plas
    LP32517-2
    • System Core
      Urine+Ser/Plas
      LP32517-2
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.66 (MIN)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Clearance aldosteronu:Objemový tok:24 hodin:Moč a sérum/plazma:Kvantitativní:
de-DEGerman (Germany)Aldosteron Renale Clearance:Volumenrate:24 Stunden:Urin und Serum oder Plasma:Quantitativ:
el-GRGreek (Greece)Αλδοστερόνη νεφρική κάθαρση:VRat:24H:Ούρα+Ορός/Πλάσμα:Qn:
Synonyms: 24H CHEM Qn VRat Αλδοστερόνη Κάθαρση Νεφρική νεφρική κάθαρση Ορός Ορός/Πλάσμα Ούρα Ούρα+Ορός/Πλάσμα Πλάσμα
es-ARSpanish (Argentina)depuración renal de aldosterona:índice de volumen:24 horas:orina:cuantitativo:
es-ESSpanish (Spain)Aldosterona Aclaramiento renal:Indice de volumen:24 horas:Orina y suero o plasma:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Aclaramiento renal de aldosterona:Tasa de volumen:24H:Orina y suero o plasma:Cuantitativo:
et-EEEstonian (Estonia)Aldosteroon renaalne kliirens:VRat:24 tunni:U+S/P:Qn:
Synonyms: Kvantitatiivne Mahu määr Plasma Seerum Seerum või plasma Uriin Uriin ja seerum või plasma
fr-CAFrench (Canada)Aldostérone, Clairance rénale:Taux volumique:24 h:Urine+Sérum/Plasma:Quantitatif:
fr-FRFrench (France)Aldostérone clairance rénale:Volume/Temps:24H:Urine+Sérum/Plasma:Numérique:
fr-BEFrench (Belgium)Aldostérone Clairance rénale:Taux volumique:24 h:Urine+Sérum/Plasma:Quantitatif:
it-ITItalian (Italy)Aldosterone Clearance renale:VRat:24h:Urina+Siero/Plasma:Qn:
Synonyms: 24 Ore Chimica Plasma Siero Siero o Plasma Tasso di Volume Urine & Siero o Plasma
ko-KRKorean (Korea, Republic Of)알도스테론 콩팥 제거율:부피율:24시간:뇨+혈청/혈장:정량:
nl-NLDutch (Netherlands)aldosteron renale klaring:volume/tijd:24 uur:urine en serum of plasma:kwantitatief:
Synonyms: 24U
pl-PLPolish (Poland)Aldosteron klirens nerkowy:wskaźnik objętości w jednostce czasu:24h:mocz i surowica lub osocze:ilościowy:
Synonyms: 24 godziny
pt-BRPortuguese (Brazil)Clearance renal de Aldosterona:VRat:24H:Urina+Sor/Plas:Qn:
Synonyms: ; Aldost; vRate; Volume rate; Flow; 1 day; 24 hours; 24HR; Ur+SerPl; Ur+SerPl; UR; Urn; UA; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Cl; Kidney; Clear; Clearanc; Clearances; Clr; Chemistry
ru-RURussian (Russian Federation)Альдостерон почечный клиренс:ОбСк:24 часа:Моча+Сыв/Плаз:Колич:
Synonyms: Количественный Моча и Сыворотка или Плазма Объемная скорость Плазма Сыворотка Сыворотка или Плазма
tr-TRTurkish (Turkey)Aldosteron renal klirens:HcmOran:24Sa:İdrar+Ser/Plaz:Kant:
zh-CNChinese (China)醛固酮 肾脏清除率:体积速率:24小时:尿液+血清/血浆:定量型:
Synonyms: 1天;1日;24.0小时;一天;一日;二十四个小时;二十四小时 体积速率(单位时间);单位时间内体积的变化速率;流量 关于肾脏的 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿 & 血清或血浆;尿+血清/血浆;尿与血清或血浆;尿液 & 血清或血浆;尿液与血清或血浆 尿;小便;下泉 廓清 廓清;清除率;廓清率 廓清率 清除率 肾 肾;肾脏的;肾的;与肾脏相关的 肾清除;肾清除率;肾脏清除 肾的 肾脏的 血清或血浆 醛基甾酮;醛甾酮;醛皮质酮;醛类脂醇

Example Units

UnitSource
mL/minExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=1734-3