18476-2

Uroporphyrinogen decarboxylase [Presence] in Red Blood Cells

Active

Part Descriptions

LP15945-6 Uroporphyrinogen decarboxylase
An enzyme that catalyzes the decarboxylation of UROPORPHYRINOGEN III to coproporphyrinogen III by the conversion of four acetate groups to four methyl groups. It is the fifth enzyme in the 8-enzyme biosynthetic pathway of HEME. Several forms of cutaneous PORPHYRIAS are results of this enzyme deficiency as in PORPHYRIA CUTANEA TARDA; and HEPATOERYTHROPOIETIC PORPHYRIA. Source: National Library of Medicine, MeSH 2006

LP15945-6 Uroporphyrinogen decarboxylase
Uroprophyrinogen Decarboxylase (Upg D) deficiency of Upg D activity causes an accumulation of uroporphyrins and hepta-, hexa-, and pentacarboxyl porphyrins in the skin, subcutaneous tissues, and liver, often resulting in the most common form of porphyria, porphyria cutanea tarda (PCT). Rarely, hepatoerythropoietic porphyria (HEP) results. Photosensitivity and skin fragility occurs in both PCT and HEP. HEP presents in early childhood, while PCT usually presents in adults. PCT type I and type III are associated with normal red cell Upg D activity, while PCT type II will have decreased red cell Upg D activity. About 20% of porphphyria cutanea tartada patients are PCT type II. Information from Tietz Clinical Guide to Laboratory Tests, A.Wu, 4th ed, 2006. Source: Regenstrief Institute

LOINC Names Get Info

Fully-Specified Name: Uroporphyrinogen decarboxylase:PrThr:Pt:RBC:Ord:
Long Common Name: Uroporphyrinogen decarboxylase [Presence] in Red Blood Cells
Short Name: URO-D RBC Ql
Display Name: Uroporphyrinogen decarboxylase Ql (RBC)
Consumer Name Alpha Get Info: Uroporphyrinogen decarboxylase, Red blood cells

Part Model Get Info

Component
Uroporphyrinogen decarboxylase
LP15945-6
- Analyte
  Uroporphyrinogen decarboxylase
  LP15945-6
  - Component Numerator
    Uroporphyrinogen decarboxylase
    LP15945-6
    - Component Numerator Core
      Uroporphyrinogen decarboxylase
      LP15945-6
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
RBC
LP7536-8
- System Core
  RBC
  LP7536-8
- Super System
  NULL
Scale
Ord
LP7751-3
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 1.0l
Last Updated: Version 2.73 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 18422

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Uroporfyrinogendekarboxyláza:Přítomnost nebo práh:Časový bod:Erytrocyty:Ordinální:
el-GR	Greek (Greece)	Ουροπορφυρογόνος αποκαρβοξυλάση:PrThr:Pt:Ερυθρά αιμοσφαίρια:Ord: Synonyms: CHEM Ord PrThr Pt Ερυθρά αιμοσφαίρια Ουροπορφυρογόνος αποκαρβοξυλάση
es-AR	Spanish (Argentina)	uroporfirinógeno descarboxilasa:concentración arbitraria:punto en el tiempo:eritrocitos:ordinal:
es-ES	Spanish (Spain)	Uroporfirinógeno decarboxilasa:PrThr:Punto temporal:Glóbulos rojos:Ord:
es-MX	Spanish (Mexico)	Uroporfirinógeno descarboxilasa:Presencia o umbral:Punto temporal:Eritrocitos:Ordinal:
et-EE	Estonian (Estonia)	Uroporfürinogeeni dekarboksülaas:PrThr:Pt:RBC:Ord: Synonyms: Erütrotsüüdid Järgarvuline Juhuslik
fr-CA	French (Canada)	Uroporphyrinogène décarboxylase:Présence-Seuil:Temps ponctuel:GR:Ordinal:
fr-FR	French (France)	Uroporphyrinogène décarboxylase:Présence/Seuil:Ponctuel:Érythrocytes:Qualitatif:
fr-BE	French (Belgium)	Uroporphyrinogène décarboxylase:PrThr:Temps ponctuel:GR:Ordinal:
it-IT	Italian (Italy)	Uroporfirinogeno decarbossilasi:PrThr:Pt:RBC:Ord: Synonyms: Chimica Globuli rossi Presenza o Soglia Punto nel tempo (episodio)
ko-KR	Korean (Korea, Republic Of)	우로포르피리노겐 디카르복실라아제:임의농도:검사시점:적혈구:순위척도:
nl-NL	Dutch (Netherlands)	uroporfyrinogeendecarboxylase:aanwezigheid:moment:erytrocyten:ordinaal: Synonyms: rode bloedcellen
pl-PL	Polish (Poland)	Dekarboksylaza uroporfirynogenu:granica wykrywalności:punkt w czasie:krwinki czerwone:uporządkowany:
pt-BR	Portuguese (Brazil)	Uroporfirinogênio decarboxilase:ACnc:Pt:Eritroc:Ord: Synonyms: ; URO-D; Upg D; UPGD; Arbitrary concentration; Point in time; Random; Erythrocytes; Red blood corpusles; Red blood cells; Ql; Ordinal; QL; Qualitative; Qual; Screen; Uroporhngn; Uroporphrg; Urophorph; URO; Chemistry
ru-RU	Russian (Russian Federation)	Уропорфириноген декарбоксилаза:PrThr:ТчкВрм:Эритроциты:Пор: Synonyms: Порядковый Точка во времени;Момент Уропорфириноген-декарбоксилаза
tr-TR	Turkish (Turkey)	Üroporfirinojen dekarboksilaz:MevcEşik:Zmlı:Eritrosit:Srl: Synonyms: Mevcut RBC
zh-CN	Chinese (China)	尿卟啉原脱羧酶:存在情况或阈值:时间点:红细胞:序数型: Synonyms: RBC;RBCS;红血球;红血细胞;赤血球 Upg D;UPGD;URO-D;六氢尿卟啉脱羧酶依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型六氢尿卟啉化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=18476-2

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.