19107-2
Histoplasma capsulatum Ag [Units/volume] in Serum by Radioimmunoassay (RIA)
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Part Description
LP16650-1 Histoplasma capsulatum
Histoplasmosis capsulatum is a dimorphic fungal pathogen with filamentous or yeast forms,depending on nutritional factors and temperature.The M antigen is a well-known glycoprotein used as a diagnostic antigen for acute histoplasmosis as it induces the first precipitins during disease. Monoclonal antibodies (mAbs) to the M antigen have been found to modify the pathogenesis of histoplasmosis.Given the shortcomings of current therapies, the administration of mAbs is being investigated. PMID: 22347215 The H band is less commonly seen than the M band and is indicative of chronic or severe acute infections with H capsulatum.
H. capsulatum is found in nature primarily as a saprophytic mold. The mold form is comprised of hyaline septate hyphae, which produce two different asexual reproduction structures, macroconidia and microconidia. The micronidia are believed to be responsible for disease propagation since their 2-6 µm size is well suited for disposition into the distal alveoli. Infection is typically acquired through inhalation of fungal propagules upon disturbances of contaminated soil or excreta. Environmental and genetic factors influence disease manifestations which can range from asymptomatic or mild influenza-like disease to a disseminated sepsis form. Manifestations depend on the magnitude of exposure, the host's immunological status and the virulence of the infective strain. Reactivation of latent infection can result in significant disease, particularly for immunosuppressed individuals. Despite the availability of potent antifungal drugs, nearly one in ten patients hospitalized with histoplasmosis dies. PMID: 17223625
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Histoplasma capsulatum Ag
- Property
- ACnc
- Time
- Pt
- System
- Ser
- Scale
- Qn
- Method
- RIA
Additional Names
- Short Name
- H capsul Ag Ser RIA-aCnc
- Display Name
- H. capsulatum Ag RIA Qn (S)
- Consumer Name Alpha Get Info
- Histoplasma capsulatum antigen, Blood
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 1.0l
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 19005
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Histoplasma capsulatum Ag: Synonyms: RIA |
es-AR | Spanish (Argentina) | [antígeno de] Histoplasma capsulatum [Ag]: |
es-ES | Spanish (Spain) | Histoplasma capsulatum Antígeno: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Histoplasma capsulatum Ag: |
et-EE | Estonian (Estonia) | Histoplasma capsulatum antigeen: Synonyms: Juhuslik Kvantitatiivne Radioimmuunmeetod Seerum |
fr-CA | French (Canada) | Histoplasma capsulatum, Ag: |
fr-FR | French (France) | Histoplasma capsulatum Ag: |
fr-BE | French (Belgium) | Histoplasma capsulatum Ag: Synonyms: Antigène Radio-immuno-essai |
it-IT | Italian (Italy) | Histoplasma capsulatum, Ag: Synonyms: Concentrazione Arbitraria Dosaggio radioimmulogico (RIA) Microbiologia Punto nel tempo (episodio) Siero |
ko-KR | Korean (Korea, Republic Of) | 히스토플라스마 캡슐라툼 항원: |
nl-NL | Dutch (Netherlands) | Histoplasma capsulatum Ag: Synonyms: antigeen |
pt-BR | Portuguese (Brazil) | Histoplasma capsulatum Ag: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Histoplasma capsulatum Аг: Synonyms: Количественный Произвольная концентрация Радиоиммуноанализ (РИА) Сыворотка Точка во времени; |
tr-TR | Turkish (Turkey) | Histoplazma Kapsulatum Ag: Synonyms: Antijen |
zh-CN | Chinese (China) | 荚膜组织胞浆菌 抗原: Synonyms: Ag 任意型浓度(单位体积); |
Example Units
Unit | Source |
---|---|
units | REGENSTRIEF |
[arb'U]/mL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=19107-2
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