Version 2.77

Part Description

LP18868-7   Amphetamine
Amphetamine (AMPH) is a drug that stimulates both the central and peripheral nervous systems and is used to treat attention-deficit/hyperactivity disorder, narcolepsy and obesity. PMID: 17209801 AMPH increases extracellular monoamine neurotransmitters in the brain including dopamine, serotonin and norepinephrine. AMPH promotes presynaptic release of the neurotransmitters rather than blocking their re-uptake. Physiological responses to AMPH use include increased blood pressure, increased heart rate, increased body temperature, relaxed bronchial muscle and depressed appetite. Abuse of AMPH can cause powerful psychological dependence, tolerance, mild physical dependence associated with tachycardia, restlessness, irritability, insomnia, personality changes and an intense form of chronic intoxication psychosis similar to schizophrenia. Long-term users of AMPH can experience depression, impaired memory and motor skills most likely due to a drop in dopamine transporters and damage to dopaminergic and serotonergic neurons. Excretion of AMPH is in the urine and the rate of elimination is dependent on the pH of the urine. Urine with an alkaline pH has an excretion rate of 18-34 hours while that of acid urine is 7-14 hours.(Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, Seventh Edition; Carl A. Burtis; David E. Bruns) Source: Regenstrief LOINC

Reference Information

Type Source Reference
Mapping Guidance Regenstrief Help CAUTION: Amphetamine (singular) defines one compound. Amphetamines (plural) specifies a class of compounds, e.g. methamphetamine, amphetamine, MDMA (ecstasy), MDEA (Eve), etc. Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations

Fully-Specified Name

Component
Amphetamine
Property
PrThr
Time
Pt
System
Urine
Scale
Ord
Method
Screen

Additional Names

Short Name
Amphet Ur Ql Scn
Display Name
Amphetamine Screen Ql (U)
Consumer Name Alpha Get Info
Amphetamine, Urine

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 1.0l
Last Updated
Version 2.73
Change Reason
The Property has been changed from ACnc to reflect new model for ordinal terms; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
452

Member of these Panels

LOINC Long Common Name
69739-1 Drugs of abuse panel - Urine by Screen method
55419-6 Home drug screening panel - Urine
99107-5 Stimulants drug panel - Urine by Screen method

Member of these Groups Get Info

LOINC Group Group Name
LG37607-5 Amphetamine|ANYProp|ANYTm|ANYSys|ANYMeth

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) anfetamina:concentración arbitraria:punto en el tiempo:orina:ordinal:tamizaje
es-ES Spanish (Spain) Anfetamina:PrThr:Punto temporal:Orina:Ord:Cribado toxicológico
es-MX Spanish (Mexico) Anfetamina:Presencia o umbral:Punto temporal:Orina:Ordinal:Pantalla de toxicología
fr-CA French (Canada) Amphétamine:Présence-Seuil:Temps ponctuel:Urine:Ordinal:Dépistage
fr-FR French (France) Amphétamine:Présence/Seuil:Ponctuel:Urine:Qualitatif:Dépistage
fr-BE French (Belgium) Amphétamine:PrThr:Temps ponctuel:Urine:Ordinal:Dépistage
it-IT Italian (Italy) Anfetamina:PrThr:Pt:Urine:Ord:Screening
Synonyms: Livelli farmacologici e tossicologia Presenza o Soglia Punto nel tempo (episodio) Screening tossicologico
ko-KR Korean (Korea, Republic Of) 암페타민:임의농도:검사시점:뇨:순위척도:선별
nl-NL Dutch (Netherlands) amfetamine:aanwezigheid:moment:urine:ordinaal:screening
pt-BR Portuguese (Brazil) Anfetamina:ACnc:Pt:Urina:Ord:Triagem
Synonyms: ; Amphet; Ampht; Amphetam; Amph; Amphetamines; Speed; Arbitrary concentration; Point in time; Random; Ur; UR; Urn; UA; Ql; Ordinal; QL; Qualitative; Qual; Scn; Scr; Scrn; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU Russian (Russian Federation) Амфетамин:PrThr:ТчкВрм:Моча:Пор:Скрининг
Synonyms: Порядковый Токсикологический скрининг Точка во времени;Момент
tr-TR Turkish (Turkey) Amfetamin:MevcEşik:Zmlı:İdrar:Srl:Tarama
Synonyms: Mevcut
uk-UA Ukrainian (Ukraine) Амфетамін:Наявність або Поріг:МоментЧасу:Сеча:Порядково:Токсикологічний скринінг
Synonyms: Addiction; Amph; Amphet; Amphetam; Amphetamines; Ampht; DRUG/TOXICOLOGY; Drugs; Drugs of abuse; Illicit; Ordinal; Point in time; PotentialForAbuse; PR; QL; Qual; Qualitative; Random; Scn; Scr; Screen; Scrn; Speed; UA; UniversalLabOrders; UR; Urn
zh-CN Chinese (China) 苯丙胺:存在情况或阈值:时间点:尿液:序数型:毒理学筛查试验
Synonyms: C9H13N;安非他明;苯异丙胺;苯齐巨林 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 尿;小便;下泉 时刻;随机;随意;瞬间 毒品 毒品类 筛查 筛查方法;筛查法;筛查试验 筛查试验 筛选试验 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 过筛 过筛试验

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=19343-3