Version 2.78

Part Description

LP14543-0   Cancer Ag 125
CA 125 is an antigenic determinant associated with a mucin-like glycoprotein, molecular weight exceeding 500,000 Daltons. This determinant is recognized by the murine monoclonal antibody OC 125, which reacts with over 80% of epithelial ovarian cancers. Elevated CA 125 levels have been reported in subjects with serous, endometrioid, clear cell, and undifferentiated ovarian carcinoma adenocarcinoma of the endometrium or fallopian tube, as well as some nongynocologic malignancies and certain nonmalignant conditions. Elevated levels also have been observed in pregnant women, most often during the first trimester. CA 125 levels may have significant value in monitoring ovarian carcinoma patients. A persistently rising CA 125 value may be associated with progressive malignant disease and poor therapeutic response. A declining CA 125 value is indicative of favorable prognosis and good response to treatment. CA 125 levels may help predict whether an invasive second-look procedure such as laparoscopy or laparotomy is required after treatment for epithelial ovarian cancer.
I.A. KOELMA, M. NAP, C.J. RODENBURG, G.J. FLEUREN (1987) The value of tumour marker CA 125 in surgical pathology
Histopathology 11 (3) , 287-294 doi:10.1111/j.1365-2559.1987.tb02633. Source: Regenstrief Institute

Reference Information

Type Source Reference
Mapping Guidance Regenstrief Help Usually reported as a quantitative test in ser/plas [LOINC: 10334-1]. Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations

Fully-Specified Name

Component
Cancer Ag 125
Property
PrThr
Time
Pt
System
Ser/Plas
Scale
Ord
Method

Additional Names

Short Name
Cancer Ag125 SerPl Ql
Display Name
Cancer Ag 125 Ql
Consumer Name Alpha Get Info
Cancer Ag 125, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
3593

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Καρκινικό αντιγόνο 125:PrThr:Χρονική στιγμή:Ορός/Πλάσμα:Τακτική:
Synonyms: CA 125
es-AR Spanish (Argentina) antígeno 125 del cáncer:concentración arbitraria:punto en el tiempo:suero/plasma:ordinal:
es-ES Spanish (Spain) Ag de cáncer 125:PrThr:Punto temporal:Suero o Plasma:Ord:
es-MX Spanish (Mexico) Cáncer Ag 125:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:
et-EE Estonian (Estonia) Kasvajaantigeen CA 125:PrThr:Pt:S/P:Ord:
Synonyms: Järgarvuline Juhuslik Plasma Seerum Seerum või plasma
fr-CA French (Canada) Ag carbohydraté 125:Présence-Seuil:Temps ponctuel:Sérum/Plasma:Ordinal:
fr-FR French (France) Carbohydrate antigène 125:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:
fr-BE French (Belgium) Ag carbohydraté 125:PrThr:Temps ponctuel:Sérum/Plasma:Ordinal:
Synonyms: Ca 125
it-IT Italian (Italy) Cancro, Ag 125:PrThr:Pt:Siero/Plasma:Ord:
Synonyms: Antigene 125 di cancro Chimica Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR Korean (Korea, Republic Of) 암 항원 125:임의농도:검사시점:혈청/혈장:순위척도:
nl-NL Dutch (Netherlands) CA125:aanwezigheid:moment:serum of plasma:ordinaal:
Synonyms: kanker Ag 125
pl-PL Polish (Poland) CA 125 Ag:granica wykrywalności:punkt w czasie:surowica lub osocze:półilościowy:
Synonyms: Antygen CA 125
pt-BR Portuguese (Brazil) Câncer Ag 125:ACnc:Pt:Sor/Plas:Ord:
Synonyms: ; Cancer Ag125; OC125; CA 125; Cancer antigen 125; Arbitrary concentration; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Ql; Ordinal; QL; Qualitative; Qual; Screen; Antigen; Antigens; Chemistry
ru-RU Russian (Russian Federation) Раковый Аг 125:PrThr:ТчкВрм:Сыв/Плаз:Пор:
Synonyms: Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Kanser Ag 125:MevcEşik:Zmlı:Ser/Plaz:Srl:
Synonyms: Mevcut
zh-CN Chinese (China) 癌抗原 125:存在情况或阈值:时间点:血清/血浆:序数型:
Synonyms: CA CA 125;OC125;癌 Ag 125;癌抗原 125（Cancer Antigen 125，CA 125） 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 癌 癌 Ag 癌症抗原 血清或血浆

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=2006-5