2007-3
Cancer Ag 15-3 [Presence] in Serum or Plasma
Active
Part Descriptions
LP15461-4 Cancer Ag 15-3
CA 15-3 is a tumor marker for breast cancer. It is derived from MUC1.
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Source: Wikipedia, CA 15-3
LP15461-4 Cancer Ag 15-3
Cancer antigen 15-3 (CA 15-3) is a mucin molecule and blood tumor marker used to gauge the response to treatment of invasive breast cancer. CA 15-3 is encoded by the MUC1 gene and is a transmembrane glycoprotein. CA 15-3 may contribute to the growth of breast tumors by preventing tumor cell cytolysis by cytotoxic T-cells or lymphokine-activated cells. It may also block the proliferation of T-cells by causing apoptosis. In addition, CA 15-3 has been found to be expressed over the entire cell in malignant breast tissue while normal breast tissue expresses CA 15-3 only on the apical side of the glanudular epithelial cells. The presence of CA 15-3 is not unique to patients with breast cancer, but can also be found in patients with lung, colorectal, ovarian, and pancreatic cancers. Patients with primary tumors tend to have lower levels of CA 15-3, though the average concentration and percentage of patients goes up as the tumor stage or size of the tumor increases. While only a small number of recurrences of local or regional tumors result in an increased CA 15-3 level, over 70% of patients with remote metastasis have much higher CA 15-3 levels. PMID: 10505206
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Cancer Ag 15-3
- Property
- PrThr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Ord
- Method
Additional Names
- Short Name
- Cancer Ag15-3 SerPl Ql
- Display Name
- Cancer Ag 15-3 Ql
- Consumer Name Alpha Get Info
- Cancer Ag 15-3, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 3887
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Καρκινικό αντιγόνο 15-3: Synonyms: CA 15‐3 |
| es-AR | Spanish (Argentina) | antígeno cáncer 15-3: |
| es-ES | Spanish (Spain) | Antígeno CA 15-3: |
| es-MX | Spanish (Mexico) | Cáncer Ag 15-3: |
| et-EE | Estonian (Estonia) | Kasvajaantigeen CA 15-3: Synonyms: Järgarvuline Juhuslik Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Ag carbohydraté 15-3: |
| fr-FR | French (France) | Carbohydrate antigène 15.3: |
| fr-BE | French (Belgium) | Ag carbohydraté 15-3: Synonyms: Ca 15.3 |
| it-IT | Italian (Italy) | Cancro, Ag 15-3: Synonyms: Antigene 15-3 di cancro Chimica Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 암 항원 15-3: |
| nl-NL | Dutch (Netherlands) | CA15.3: Synonyms: kanker Ag 15-3 |
| pl-PL | Polish (Poland) | CA 15-3 Ag: Synonyms: Antygen CA 15-3 |
| pt-BR | Portuguese (Brazil) | Câncer Ag 15-3: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Раковый Аг 15-3: Synonyms: Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Kanser Ag 15-3: Synonyms: Mevcut |
| zh-CN | Chinese (China) | 癌抗原 15-3: Synonyms: Ⅲ CA CA 153; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=2007-3
LOINC Copyright
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