LP15461-4
Cancer Ag 15-3
Active
Descriptions
CA 15-3 is a tumor marker for breast cancer. It is derived from MUC1. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, CA 15-3
Cancer antigen 15-3 (CA 15-3) is a mucin molecule and blood tumor marker used to gauge the response to treatment of invasive breast cancer. CA 15-3 is encoded by the MUC1 gene and is a transmembrane glycoprotein. CA 15-3 may contribute to the growth of breast tumors by preventing tumor cell cytolysis by cytotoxic T-cells or lymphokine-activated cells. It may also block the proliferation of T-cells by causing apoptosis. In addition, CA 15-3 has been found to be expressed over the entire cell in malignant breast tissue while normal breast tissue expresses CA 15-3 only on the apical side of the glanudular epithelial cells. The presence of CA 15-3 is not unique to patients with breast cancer, but can also be found in patients with lung, colorectal, ovarian, and pancreatic cancers. Patients with primary tumors tend to have lower levels of CA 15-3, though the average concentration and percentage of patients goes up as the tumor stage or size of the tumor increases. While only a small number of recurrences of local or regional tumors result in an increased CA 15-3 level, over 70% of patients with remote metastasis have much higher CA 15-3 levels. PMID: 10505206 Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Cancer Ag 15-3
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Cancer Ag15-3
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP15461-4
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 癌抗原 15-3 Synonyms: CA 153; |
| fr-CA | French (Canada) | Ag carbohydraté 15-3 |
| et-EE | Estonian (Estonia) | Kasvajaantigeen CA 15-3 |
| es-ES | Spanish (Spain) | Antígeno CA 15-3 |
| it-IT | Italian (Italy) | Cancro, Ag 15-3 Synonyms: Antigene 15-3 di cancro |
| el-GR | Greek (Greece) | Καρκινικό αντιγόνο 15-3 Synonyms: CA 15‐3 |
| tr-TR | Turkish (Turkey) | Kanser Ag 15-3 |
| ru-RU | Russian (Russian Federation) | Раковый Аг 15-3 |
| nl-NL | Dutch (Netherlands) | CA15.3 Synonyms: kanker Ag 15-3 |
| fr-BE | French (Belgium) | Ag carbohydraté 15-3 Synonyms: Ca 15.3 |
| pl-PL | Polish (Poland) | CA 15-3 Ag Synonyms: Antygen CA 15-3 |
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright