2029-7
Deprecated Carboxyhemoglobin
Deprecated
Status Information
- Status
- DEPRECATED
- Reason
- Erroneous
- Comment
- Property/scale mismatch
Part Description
LP21418-6 Carboxyhemoglobin
Carboxyhemoglobin, a complex of hemoglobin and carbon monoxide, is a marker of exposure to inhaled carbon monoxide (CO). CO gas is produced from almost any fire as the result of incomplete combustion to CO2, and the normal individual will have about 1 or 2 % of their hemoglobin in the form of carboxyhemoglobin, and up to 5% depending on environmental circumstances. Smokers can have levels as high as 10% or even higher. Poisoning with CO generally results from improperly vented furnaces, automobile exhaust, and fires, with carboxyhemoglobin:hemoglobin ratios of 10-30% found in symptomatic individuals and 30-90% in fatalities. With a 230 fold greater affinity, inhaled CO avidly replaces oxygen at its hemoglobin binding site. In addition, replacing even one of the 4 sites of the hemoglobin tetramer with CO prevents dissociation of the remaining 3 oxygen moieties to tissue (known as left shift of O2 dissociation curve). As a result, hemoglobin remains red and skin color is rosy despite physiologic anoxia. Although measuring carboxyhemoglobin can confirm carbon monoxide poisoning, the level does not always correlate with the clinical picture; carbon monoxide poisoning involves other mechanisms as well, including binding to myoglobin, cytochrome oxidase, and direct effects on the central nervous system.
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Carboxyhemoglobin:
SFr: Pt: RBC: Ord: - Long Common Name
- Deprecated Carboxyhemoglobin
- Short Name
- Deprecated COHgb Fr RBC
- Display Name
- Carboxyhemoglobin Ql (RBC)
- Consumer Name Alpha Get Info
- Carboxyhemoglobin, Red blood cells
Part Model Get Info
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.46 (DEL)
- Change Reason
- Set CHNG_TYP=DEL since the term is deprecated
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Karboxyhemoglobin: |
| el-GR | Greek (Greece) | Καρβοξυαιμοσφαιρίνη: Synonyms: CHEM Ord Pt SFr Ερυθρά αιμοσφαίρια Καρβοξυαιμοσφαιρίνη |
| es-AR | Spanish (Argentina) | carboxihemoglobina: |
| es-ES | Spanish (Spain) | Carboxihemoglobina: |
| es-MX | Spanish (Mexico) | Carboxihemoglobina: |
| et-EE | Estonian (Estonia) | Karboksühemoglobiin: Synonyms: Aine fraktsioon Erütrotsüüdid Järgarvuline Juhuslik |
| fr-CA | French (Canada) | Carboxyhémoglobine: |
| fr-BE | French (Belgium) | Carboxyhémoglobine: Synonyms: Fraction. Concentration HbCO |
| fr-FR | French (France) | Carboxyhémoglobine: |
| it-IT | Italian (Italy) | Carbossiemoglobina: Synonyms: Chimica Frazione di Sostanza Globuli rossi Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | carboxyhemoglobine: Synonyms: rode bloedcellen |
| pl-PL | Polish (Poland) | Karboksyhemoglobina: Synonyms: Karboksyhemoglobina |
| pt-BR | Portuguese (Brazil) | Carboxihemoglobina: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Карбоксигемоглобин: Synonyms: Мольная доля; |
| tr-TR | Turkish (Turkey) | Karboksihemoglobin: Synonyms: RBC |
| zh-CN | Chinese (China) | 碳氧血红蛋白: Synonyms: CO 血红蛋白; |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://