20736-5
Cache valley virus neutralizing antibody [Presence] in Serum by Neutralization test
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Part Descriptions
LP19592-2 Cache valley virus
Cache Valley virus (CVV), a mosquito-borne member of the Bunyamwera serogroup, family Bunyaviridae, genus Orthobunyavirus, is geographically widespread in North America, where it circulates between mosquitoes and mammals. Human cases are rare, and occur from late spring through early fall. CVV can cause meningitis and encephalitis, and symptoms include fever, headache, vomiting, and rash. Hosts include deer, cattle, horses and sheep.
Source: Centers for Disease Control and Prevention
, Cache valley virus
LP19592-2 Cache valley virus
Cache Valley virus (CVV) was isolated in Cache Valley, Utah, in 1956. CVV is a mosquito borne member of the Bunyamwera serogroup belonging to the family Peribunyaviridae, genus Orthobunyavirus [NCBI Taxonomy: 80935] [CDC:cache-valley/healthcare-providers/index.html]. The primary vectors are unknown; however CVV has been isolated in multiple mosquito species including Anopheles, Culiseta, Coquillettidia, Aedes , and most commonly Anopheles quadrimaculatus PMID: 16704854 [CDC: cache-valley/healthcare-providers/index.html]. CVV is neuroinvasive and rarely diagnosed in North America PMID: 16704854. Symptoms produced can be life threatening and include fever, encephalitis, or meningitis PMID: 25962774.
Source: Regenstrief LOINC
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Cache valley virus Ab.Neut
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Neut
Additional Names
- Long Common Name
- Cache valley virus neutralizing antibody [Presence] in Serum by Neutralization test
- Short Name
- CVV NAb Ser Ql Nt
- Display Name
- Cache valley virus neut ab Neut test Ql (S)
- Consumer Name Alpha Get Info
- Cache Valley virus neutralizing antibody, Blood
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 1.0m
- Last Updated
- Version 2.72 (NAM)
- Change Reason
- Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.; Previous Releases: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Ιός Cache valley Ab.Neut: Synonyms: PrThr |
| es-AR | Spanish (Argentina) | CACHE VALLEY VIRUS: |
| es-ES | Spanish (Spain) | Virus de Cache valley Anticuerpos antineutrófilos: |
| es-MX | Spanish (Mexico) | Virus del valle del caché Ab: |
| fr-FR | French (France) | Virus de Cache Valley Ac neutralisant: |
| fr-CA | French (Canada) | Virus Cache Valley Ac.neut: |
| it-IT | Italian (Italy) | Cache valley, virus Ab.Neut: Synonyms: anticorpo Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Test di neutralizzazione Virus di Cache valley |
| ko-KR | Korean (Korea, Republic Of) | Cache valley virus Antibody: |
| nl-NL | Dutch (Netherlands) | Cache valley virus As.neutraliserend: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Wirus doliny Cache Ab.Neutralizujące: Synonyms: Przeciwciała do wirusa doliny Cache Przeciwciałd nautralziujące do wirusa doliny Cachew Wirus doliny Cache |
| pt-BR | Portuguese (Brazil) | Cache valley vírus Ac: Synonyms: ; |
| zh-CN | Chinese (China) | 卡赤谷病病毒 抗体.中和: Synonyms: Ab; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=20736-5
LOINC Copyright
Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://