21598-8

Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

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Part Description

LP14853-3 Varicella zoster virus
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.[http://jvi.asm.org/content/88/24/13936.full] In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.[https://grose.lab.uiowa.edu/vzv-genomes-and-evolution] Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/ Source: Regenstrief LOINC

Fully-Specified Name

Component: Varicella zoster virus DNA
Property: PrThr
Time: Pt
System: CSF
Scale: Ord
Method: Probe.amp.tar

Additional Names

Short Name: VZV DNA CSF Ql NAA+probe
Display Name: VZV DNA NAA+probe Ql (CSF)
Consumer Name Alpha Get Info: Varicella zoster virus (VZV; Chickenpox), Spinal fluid

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 1.0m
Last Updated: Version 2.73
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 3652

Member of these Panels

LOINC	Long Common Name
99087-9	Meningitis+Encephalitis pathogens panel - Cerebral spinal fluid by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG32750-8	Varicella zoster virus

Language Variants Get Info

Tag	Language	Translation
de-AT	German (Austria)	Synonyms: Varizella Zoster Virus DNA /Liquor PCR
de-DE	German (Germany)	Varicella-Zoster-Virus DNA:Nachweis oder Schwellenwert:Zeitpunkt:Liquor:Ordinal:Zielfragmentamplifikation mit Sondendetektion Synonyms: Human alphaherpesvirus 3; VZV; Zerebrospinalflüssigkeit
el-GR	Greek (Greece)	Ιός ανεμευλογιάς-έρπητα ζωστήρα DNA:PrThr:Χρονική στιγμή:ΕΝΥ:Τακτική:Ανιχνευτής με ενίσχυση στόχου Synonyms: VZV
es-AR	Spanish (Argentina)	ADN del virus Varicela-zoster:concentración arbitraria:punto en el tiempo:líquido cefalorraquídeo:ordinal:sonda.amplificación.blanco
es-ES	Spanish (Spain)	Virus Varicella zoster ADN:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Sonda con amplificación dirigida
es-MX	Spanish (Mexico)	ADN del virus de la varicela zóster:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-CA	French (Canada)	Virus varicelle-zona, ADN:Présence-Seuil:Temps ponctuel:LCR:Ordinal:Sonde avec amplification de la cible
fr-FR	French (France)	Varicelle zona virus ADN:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:PCR amplification de cible
fr-BE	French (Belgium)	Virus varicelle-zona ADN:PrThr:Temps ponctuel:LCR:Ordinal:Sonde avec amplification de la cible Synonyms: VZV
it-IT	Italian (Italy)	Varicella zoster, virus DNA:PrThr:Pt:LCS:Ord:Sonda.amp.tar Synonyms: Liquido cerebrospinale Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus della varicella zoster
ko-KR	Korean (Korea, Republic Of)	수두 대상포진 바이러스 디옥시리보핵산:임의농도:검사시점:뇌척수액:순위척도:DNA 탐색자.증폭.표적
nl-NL	Dutch (Netherlands)	varicella-zostervirus DNA:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:probe-detectie Synonyms: probe.amp.tar Varicella zoster virus
pt-BR	Portuguese (Brazil)	Varicella zoster vírus DNA:ACnc:Pt:LCR:Ord:Sonda com limite de detecção da amplificação de alvo Synonyms: ; VZV; Shingles; Chicken pox; Human herpesvirus 3; HHV-3; Chickenpox; Herpes zoster; VZ; Chicken pox virus; Deoxyribonucleic acid; Arbitrary concentration; Point in time; Random; Cerebral spinal fluid; Spinal Fluid; Cerebrospinal Fl; Spinal Flu; Spinal Fld; Ql; Ordinal; QL; Qualitative; Qual; Screen; PCR; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Amplified; Microbiology
ru-RU	Russian (Russian Federation)	Varicella zoster вирус ДНК:PrThr:ТчкВрм:ЦСЖ:Пор:Проба.усил.миш Synonyms: ДНК проба;ДНК зонд Порядковый Проба с мишени усилением Точка во времени;Момент Цереброспинальная жидкость
tr-TR	Turkish (Turkey)	Varicella zoster virüsü DNA:MevcEşik:Zmlı:BOS:Srl:Prob.amf.hdf Synonyms: Mevcut
zh-CN	Chinese (China)	水痘带状疱疹病毒 DNA:存在情况或阈值:时间点:脑脊液:序数型:探针法.基因扩增.靶向 Synonyms: CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 HHV-3 DNA HHV-3;VZ;VZV;人类疱疹病毒 3 型;人类疱疹病毒 III 型;带状疱疹;水痘;水痘带状疱疹;水痘病毒;Varicella zoster virus;水痘-带状疱疹病毒 VZV DNA 人类疱疹病毒 3 型 DNA 人类疱疹病毒 III 型 DNA 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向去氧核糖核酸;脱氧核糖核酸去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA）存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间水痘病毒 DNA 经过扩增的脊液脊髓液脑脊液（Cerebral spinal fluid，CSF）脑脊髓液脱氧核糖核酸探针

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