21740-6
TRAF3 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal
Active
Part Description
LP19770-4 TRAF3 gene
The TRAF3 gene (TNF receptor-associated factor 3) [HGNC Gene ID:12033] is located on chromosome 14q32.32. The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq, Dec 2010] [NCBI Gene ID:7187]
Source: National Center for Biotechnology Information (NCBI) Gene
Fully-Specified Name
- Component
- TRAF3 gene targeted mutation analysis
- Property
- Prid
- Time
- Pt
- System
- Bld/Tiss
- Scale
- Nom
- Method
- Molgen
Additional Names
- Long Common Name
- TRAF3 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal
- Short Name
- TRAF3 gene Mut Anl Bld/T
- Display Name
- TRAF3 gene targeted mutation analysis Molgen Nom (Bld/Tiss)
- Consumer Name Alpha Get Info
- TRAF3 gene targeted mutation analysis, Blood or tissue specimen
Basic Attributes
- Class
- MOLPATH.MUT
- Type
- Laboratory
- First Released
- Version 1.0m
- Last Updated
- Version 2.63
- Change Reason
- Based on LOINC Committee review (June 2016), "targeted" was added to the Component to clarify that this test is looking for a specific set of mutations as described in the LOINC User Guide under the Molecular Genetics section.
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Gen TRAF3 Analisis de mutaciones: |
| es-AR | Spanish (Argentina) | análisis de la mutación del gen TRAF3: |
| es-MX | Spanish (Mexico) | Análisis de mutaciones dirigidas al gen TRAF3: |
| fr-FR | French (France) | TRAF3 gène mutation cible trouvée: |
| it-IT | Italian (Italy) | TRAF3, gene analisi di mutazione mirata: Synonyms: Gene TRAF3 Genetica molecolare Mutazione genica Patologia molecolare Presenza o Identità Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & |
| ko-KR | Korean (Korea, Republic Of) | TRAF3 유전자 돌연변이 분석: |
| nl-NL | Dutch (Netherlands) | TRAF3-gen doelgerichte mutatie-analyse: Synonyms: molgen targeted TRAF3 gen |
| pt-BR | Portuguese (Brazil) | TRAF3 análise de mutação genética: Synonyms: TNF receptor associated factor 3; |
| ru-RU | Russian (Russian Federation) | TRAF3 ген исследование на мутацию: Synonyms: Кровь Кровь или Ткань Номинальный; |
| tr-TR | Turkish (Turkey) | TRAF3 geni Mutasyon analizi: |
| zh-CN | Chinese (China) | TRAF3 基因 突变分析: Synonyms: CAP1; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=21740-6
LOINC Copyright
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