Version 2.78

Part Descriptions

LP19776-1   BCL6 gene rearrangements
The protein encoded by the BCL6 gene arrangements is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. Source: National Center for Biotechnology Information (NCBI) Gene, BCL6 gene rearrangements

LP19776-1   BCL6 gene rearrangements
The BCL6 gene (B-cell CLL/lymphoma 6) [HGNC Gene ID:1001] is located on chromosome 3q27. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2008] [NCBI Gene ID:604] Source: National Center for Biotechnology Information (NCBI) Gene

Fully-Specified Name

Component
BCL6 gene rearrangements
Property
Arb
Time
Pt
System
Bld/Tiss
Scale
Ord
Method
Molgen

Additional Names

Long Common Name
BCL6 gene rearrangements [Presence] in Blood or Tissue by Molecular genetics method
Short Name
BCL6 gene Rear Bld/T Ql
Display Name
BCL6 rearrangements Molgen Ql (Bld/Tiss)
Consumer Name Alpha Get Info
BCL6 rearrangements, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.REARRANGE
Type
Laboratory
First Released
Version 1.0m
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
13110

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) reordenamientos del gen BCL6:arbitrario:punto en el tiempo:sangre entera/tejido:ordinal:genética molecular
es-ES Spanish (Spain) Reordenamientos del gen BCL6:Arbitrario:Punto temporal:Sangre o tejido:Ord:Genética molecular
es-MX Spanish (Mexico) Reordenamientos del gen BCL6:Arbitrario:Punto temporal:Sangre o tejido:Ordinal:Genética molecular
fr-FR French (France) BCL6 gène réarrangements:Arbitraire:Ponctuel:Sang/Tissu:Qualitatif:Biologie moléculaire
it-IT Italian (Italy) BCL6, riarrangiamenti gene:Arb:Pt:Sangue/Tess:Ord:Molgen
Synonyms: Arbitrario Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Riarrangiamenti gene BCL6 Riarrangiamento genico Sangue Sangue o Tessuto Tessuto & Strisci
ko-KR Korean (Korea, Republic Of) BCL6 유전자 재배열:임의적분:검사시점:전혈/조직:순위척도:분자유전
nl-NL Dutch (Netherlands) BCL6-genherschikking:aanwezigheid:moment:bloed of weefsel:ordinaal:moleculair genetisch onderzoek
Synonyms: BCL6 gen translocaties molgen
pt-BR Portuguese (Brazil) BCL6 rearranjos do gene:Arb:Pt:Sg/Tecido:Ord:Genética molecular
Synonyms: ; BCL6 gene Rear; B-cell CLL; Zinc finger protein 51; Non-Hodgkin lymphoma; Lymphoma 6; BCL5; LAZ3; ZNF51; BCL-6; Arbitrary; Point in time; Random; Bld/T; Tissue; Bld/T; Blood; WB; Whole blood; Ql; Ordinal; QL; Qualitative; Qual; Screen; PCR; Molecular genetics; Rearrang; Rearr; Rearrangement; MOLPATH.REARRANGEMENTS; MOLPATH.REARRANGEMENTS; Molecular pathology
ru-RU Russian (Russian Federation) BCL6 ген перестройки:Произв:ТчкВрм:Кр/Тк:Пор:МолГен
Synonyms: Кровь Кровь или Ткань Порядковый Произвольный Ткань и мазки Точка во времени;Момент
tr-TR Turkish (Turkey) BCL6 geni yeniden düzenlenmeler:Sç:Zmlı:Kan/Dk:Srl:Molgen
zh-CN Chinese (China) BCL6 基因重排:任意型:时间点:全血/组织:序数型:分子遗传学类实验室方法
Synonyms: BCL6 基因重排（重组）;B 细胞 CLL;B 细胞慢性淋巴细胞白血病;BCL5;LAZ3;ZNF51;慢性 B 淋巴细胞白血病;淋巴瘤 6;锌指蛋白 51;非 Hodgkin 氏淋巴瘤;非何杰金氏淋巴瘤;BCL-6 基因重排 BCL-6;B-细胞白血病/淋巴瘤 6;B细胞白血病/淋巴瘤6 任意;任意的;人工型 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 全血或组织;血液/组织;血液或组织 分子病理学.基因重排;分子病理学.重排;分子病理学试验.基因重排;分子病理学试验.重排;分子病理学试验类.重排;基因重排;重排 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 血;血液 遗传基因;遗传因子;吉恩;生物基因

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