21750-5
MYC gene rearrangements [Presence] in Blood or Tissue by Molecular genetics method
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Part Description
LP19780-3 MYC gene rearrangements
The MYC gene (v-myc avian myelocytomatosis viral oncogene homolog) [HGNC Gene ID:7553] is located on chromosome 8q24.21. The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008] [NCBI Gene ID:4609]
Source: National Center for Biotechnology Information (NCBI) Gene
Fully-Specified Name
- Component
- MYC gene rearrangements
- Property
- Arb
- Time
- Pt
- System
- Bld/Tiss
- Scale
- Ord
- Method
- Molgen
Additional Names
- Long Common Name
- MYC gene rearrangements [Presence] in Blood or Tissue by Molecular genetics method
- Short Name
- MYC gene Rear Bld/T Ql
- Display Name
- MYC gene rearrangements Molgen Ql (Bld/Tiss)
- Consumer Name Alpha Get Info
- MYC gene rearrangements, Blood or tissue specimen
Basic Attributes
- Class
- MOLPATH.REARRANGE
- Type
- Laboratory
- First Released
- Version 1.0m
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 19400
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-AR | Spanish (Argentina) | reordenamientos del gen MYC: |
es-ES | Spanish (Spain) | Reordenamientos del gen MYC: |
es-MX | Spanish (Mexico) | Reordenamientos del gen MYC: |
fr-FR | French (France) | MYC gène réarrangements: |
it-IT | Italian (Italy) | MYC, riarrangiamenti gene: Synonyms: Arbitrario Gene MYC Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Riarrangiamenti gene MYC Riarrangiamento genico Sangue Sangue o Tessuto Tessuto & |
ko-KR | Korean (Korea, Republic Of) | MYC 유전자 재배열: |
nl-NL | Dutch (Netherlands) | MYC genherschikking: Synonyms: molgen MYC gen MYC gentranslocatie |
pt-BR | Portuguese (Brazil) | MYC rearranjos do gene: Synonyms: ; |
ru-RU | Russian (Russian Federation) | MYC ген перестройки: Synonyms: Кровь Кровь или Ткань Порядковый Произвольный Ткань и мазки Точка во времени; |
tr-TR | Turkish (Turkey) | MYC geni yeniden düzenlemeler: |
zh-CN | Chinese (China) | MYC 基因重排: Synonyms: Burkitt 淋巴瘤 Burkitts 淋巴瘤 c-MYC MYC 原癌基因 MYC 基因重排(重组) v-myc myelocytomatosis viral oncogene homolog (avian); |
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