LP19780-3
MYC gene rearrangements
Active
Description
The MYC gene (v-myc avian myelocytomatosis viral oncogene homolog) [HGNC Gene ID:7553] is located on chromosome 8q24.21. The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008] [NCBI Gene ID:4609] Source: National Center for Biotechnology Information (NCBI) Gene
Basic Part Properties
- Part Name
- MYC gene rearrangements
- Part Display Name
- MYC gene rearrangements
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- MYC gene Rear
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP19780-3
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | MYC 基因重排 Synonyms: MYC 基因重排（重组） |
| et-EE | Estonian (Estonia) | MYC geeni muudatused |
| es-ES | Spanish (Spain) | Reordenamientos del gen MYC |
| it-IT | Italian (Italy) | MYC, riarrangiamenti gene Synonyms: Riarrangiamenti gene MYC |
| tr-TR | Turkish (Turkey) | MYC geni yeniden düzenlemeler |
| ru-RU | Russian (Russian Federation) | MYC ген перестройки |
| nl-NL | Dutch (Netherlands) | MYC genherschikking Synonyms: MYC gentranslocatie |
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://