Version 2.77

Description

The MYC gene (v-myc avian myelocytomatosis viral oncogene homolog) [HGNC Gene ID:7553] is located on chromosome 8q24.21. The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008] [NCBI Gene ID:4609] Source: National Center for Biotechnology Information (NCBI) Gene

Basic Part Properties

Part Display Name
MYC gene rearrangements
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
MYC gene Rear

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP19780-3

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) MYC 基因重排
Synonyms: MYC 基因重排(重组)
et-EE Estonian (Estonia) MYC geeni muudatused
es-ES Spanish (Spain) Reordenamientos del gen MYC
it-IT Italian (Italy) MYC, riarrangiamenti gene
Synonyms: Riarrangiamenti gene MYC
tr-TR Turkish (Turkey) MYC geni yeniden düzenlemeler
ru-RU Russian (Russian Federation) MYC ген перестройки
nl-NL Dutch (Netherlands) MYC genherschikking
Synonyms: MYC gentranslocatie