Version 2.78

Part Description

LP19837-1   t(14;18)(q32;q21.3)(IGH,BCL2)
Chromosomal translocation t(14;18)(q32;q21.3) IGH-BCL2 is found in follicular lymphomas (80-90%), diffuse large cell lymphomas (30%), and rarely in other lymphoproliferative disorders. It mainly occurs in B- cell non-hodgkin's lymphoma (NHL). This translocation is cytogenetically indistinguishable from t(14;18)(q32;q21) IGH-MALT1.[Atlas Genetics Oncology: t1418ID2006] FISH with probes specific to the targeted genes distinguishs between the two different rearrangements. Source: Regenstrief LOINC, t(14;18)(q32;q21) IGH/BCL2

Fully-Specified Name

Component
t(14;18)(q32;q21.3)(IGH,BCL2) fusion transcript major break points
Property
Arb
Time
Pt
System
Bld/Tiss
Scale
Ord
Method
Molgen

Additional Names

Short Name
t(14;18)(IGH,BCL2) Major Bld/T Ql
Display Name
t(14;18)(q32;q21.3)(IGH,BCL2) fusion transcript major break points Molgen Ql (Bld/Tiss)
Consumer Name Alpha Get Info
t(14;18)(q32;q21.3)(IGH,BCL2) major break point analysis, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 1.0m
Last Updated
Version 2.50
Change Reason
Updated Component part to harmonize with ISCN guidelines and current LOINC nomenclature.
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) puntos de rupturas mayores de translocación del gen T(14,18)(IGH,BCL2):arbitrario:punto en el tiempo:sangre entera/tejido:ordinal:genética molecular
es-ES Spanish (Spain) t(14;18)(q32;q21.3)(IGH,BCL2) punto de rotura mayor del transcrito de fusion:Arbitrario:Punto temporal:Sangre o tejido:Ord:Genética molecular
es-MX Spanish (Mexico) t (14; 18) (q32; q21.3) (IGH, BCL2) puntos de ruptura principales de la transcripción de fusión:Arbitrario:Punto temporal:Sangre o tejido:Ordinal:Genética molecular
fr-FR French (France) t(14;18)(q32;q21.3)(IGH,BCL2) transcrit de fusion point de rupture majeur:Arbitraire:Ponctuel:Sang/Tissu:Qualitatif:Biologie moléculaire
it-IT Italian (Italy) t(14;18)(q32;q21.3)(IGH,BCL2), punti di rottura principali di trascritto di fusione:Arb:Pt:Sangue/Tess:Ord:Molgen
Synonyms: Arbitrario Genetica molecolare Patologia molecolare Punti di rottura maggiori della traslocazione t(14,18)(IGH,BCL2) Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
ko-KR Korean (Korea, Republic Of) t(14,18)(IGH,BCL2) 유전자 전위 주변 곡점:임의적분:검사시점:전혈/조직:순위척도:분자유전
nl-NL Dutch (Netherlands) t(14;18)(q32;q21.3)(IGH,BCL2) fusietranscript major breakpoints:aanwezigheid:moment:bloed of weefsel:ordinaal:moleculair genetisch onderzoek
Synonyms: molgen
pl-PL Polish (Poland) t (14; 18) (q32; q21.3) (IGH,BCL2) główne punkty przerwania transkryptu fuzyjnego:jednostka umowna:punkt w czasie:krew lub tkanka:półilościowy:genetyka molekularna
Synonyms: Translokacja (14; 18) (q32; q21.3) (IGH,BCL2) Translokacja (14; 18) (q32; q21.3) (IGH,BCL2) główne punkty przerwania transkryptu genu fuzyjnego Translokacja(14; 18) (q32; q21.3) (IGH,BCL2) transkrypt genu fuzyjnego
pt-BR Portuguese (Brazil) t(14,18)(IGH,BCL2) translocação do gene maior ponto de quebra:Arb:Pt:Sg/Tecido:Ord:Genética molecular
Synonyms: ; t(14,18)(IGH,BCL2)Maj; BCL-2; B-cell leukemia/lymphoma 2; Arbitrary; Point in time; Random; Bld/T; Tissue; Bld/T; Blood; WB; Whole blood; Ql; Ordinal; QL; Qualitative; Qual; Screen; PCR; Molecular genetics; Follicular B cell lymphoma; t(14,18)(q32,q21); Oncogene B-cell leukemia 2; CLL; Chronic lymphatic leukemia; Follicular lymphoma; Non-Hodgkin lymphoma; T prime; Mbr; MOLPATH.TRANSLOCATION; MOLPATH.TRANSLOCATION; Molecular pathology
ru-RU Russian (Russian Federation) t(14;18)(q32;q21.3)(IGH,BCL2) слияния транскрипт major break points:Произв:ТчкВрм:Кр/Тк:Пор:МолГен
Synonyms: Кровь Кровь или Ткань Порядковый Произвольный слияния транскрипт мажорная точка разрыва Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR Turkish (Turkey) t(14;18)(q32;q21.3)(IGH,BCL2) füzyon transkriptt major kırılma noktaları:Sç:Zmlı:Kan/Dk:Srl:Molgen
zh-CN Chinese (China) t(14;18)(q32;q21.3)(IGH,BCL2) 融合转录物主要断裂点:任意型:时间点:全血/组织:序数型:分子遗传学类实验室方法
Synonyms: BCL-2;B-细胞白血病/淋巴瘤 2;B细胞白血病/淋巴瘤2 Mbr T(14,18)(IGH,BCL2) 基因易位;T(14,18)(IGH,BCL2) 易位 T(14,18)(IGH,BCL2) 基因易位主要断裂点 主要断点（Major break points，Mbr） 主要断点区 主要断点区（major breakpoint region, mbr） 主要断点类 主要断裂区 主要断裂区（major breakpoint region, mbr） 主要断裂点 主要断裂点（Major break points，Mbr） 主要断裂点类 任意;任意的;人工型 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 全血或组织;血液/组织;血液或组织 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 融合转录物（转录本、转录产物、转录子、转录）主要断裂点;融合基因转录本主要断裂点;融合转录本主要断点 血;血液

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=21809-9