22687-8
Cystine/Creatinine [Molar ratio] in Urine
Active
Part Descriptions
LP14976-2 Cystine
Cystine is an oxidized dimeric form of cysteine. It is formed by linking two cysteine residues via a disulfide bond (cys-S-S-cys) between the -SH groups. Cystine was discovered in 1810 but was not recognized as a component of proteins until it was isolated from the horn of a cow in 1899.1 Cystine is found in high concentrations in the cells of the immune system, skeletal and connective tissues, skin, digestive enzymes, and in hair. Hair and skin are 10-14% cystine.
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Source: Wikipedia, Cystine (Wikipedia)
LP14976-2 Cystine
Union of two cysteine molecules
Source: Regenstrief Institute
LP14976-2 Cystine
A covalently linked dimeric nonessential amino acid formed by the oxidation of CYSTEINE. Two molecules of cysteine are joined together by a disulfide bridge to form cystine.
Source: National Library of Medicine, MeSH 2006
LP14976-2 Cystine
Cystinuria is an inherited amino acid transport problem resulting in large amounts of cystine being excreted in the urine. Cystinuria often causes the formation of staghorn calculi or multiple large, bilateral stones. Urinary tract obstruction, infection, and renal failure are common, especially in men, due to the size and shape of the stones. Recurrence of cystine stones is common following surgical treatment. Therapy includes reducing excretion and increasing solubility of cystine.
Cystine is a hydrophilic amino acid with uncharged polar groups. Cystines' sulfhydryl group is functional in the activity of many enzymes. Increased in cystinuria which is caused by mutations in the SLC3A1 and SLC7A9 genes. (Information from ARUP Laboratories 9/14/06)
Source: Regenstrief Institute
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- Cystine/Creatinine
- Property
- SRto
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Short Name
- Cystine/Creat Ur-sRto
- Display Name
- Cystine/Creatinine (U) [Molar ratio]
- Consumer Name Alpha Get Info
- Cystine/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0n
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 11422
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 74991-1 | Amino acids panel [Molar ratio] - Urine |
| 90784-0 | Cystinuria panel - Urine |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG35282-9 | Cystine/Creatinine| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Cystin/Kreatinin-Ratio /U |
| es-AR | Spanish (Argentina) | cistina/creatinina: |
| es-MX | Spanish (Mexico) | Cistina / Creatinina: |
| es-ES | Spanish (Spain) | Cistina/Creatinina: Synonyms: Cuantitativo |
| fr-CA | French (Canada) | Cystine/Créatinine: |
| fr-FR | French (France) | Cystine/créatinine: |
| fr-BE | French (Belgium) | Cystine/Créatinine: |
| it-IT | Italian (Italy) | Cistina/Creatinina: Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza |
| ko-KR | Korean (Korea, Republic Of) | 시스틴/크레아티닌: |
| nl-NL | Dutch (Netherlands) | cystine/creatinine: Synonyms: kreatinine |
| pt-BR | Portuguese (Brazil) | Cistina/Creatinina: Synonyms: Cys-Cys; |
| ru-RU | Russian (Russian Federation) | Цистин/Креатинин: Synonyms: Количественный Мольная доля; |
| tr-TR | Turkish (Turkey) | Sistin/Kreatinin: Synonyms: SubsOranı |
| zh-CN | Chinese (China) | 胱氨酸/肌酐: Synonyms: CR; |
Example Units
| Unit | Source |
|---|---|
| mmol/mol | eCHN |
| mmol/mol{creat} | Example UCUM Units |
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright