Version 2.77

Part Descriptions

LP14976-2   Cystine
Cystine is an oxidized dimeric form of cysteine. It is formed by linking two cysteine residues via a disulfide bond (cys-S-S-cys) between the -SH groups. Cystine was discovered in 1810 but was not recognized as a component of proteins until it was isolated from the horn of a cow in 1899.1 Cystine is found in high concentrations in the cells of the immune system, skeletal and connective tissues, skin, digestive enzymes, and in hair. Hair and skin are 10-14% cystine. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Cystine (Wikipedia)

LP14976-2   Cystine
Union of two cysteine molecules Source: Regenstrief Institute

LP14976-2   Cystine
A covalently linked dimeric nonessential amino acid formed by the oxidation of CYSTEINE. Two molecules of cysteine are joined together by a disulfide bridge to form cystine. Source: National Library of Medicine, MeSH 2006

LP14976-2   Cystine
Cystinuria is an inherited amino acid transport problem resulting in large amounts of cystine being excreted in the urine. Cystinuria often causes the formation of staghorn calculi or multiple large, bilateral stones. Urinary tract obstruction, infection, and renal failure are common, especially in men, due to the size and shape of the stones. Recurrence of cystine stones is common following surgical treatment. Therapy includes reducing excretion and increasing solubility of cystine.

Cystine is a hydrophilic amino acid with uncharged polar groups. Cystines' sulfhydryl group is functional in the activity of many enzymes. Increased in cystinuria which is caused by mutations in the SLC3A1 and SLC7A9 genes. (Information from ARUP Laboratories 9/14/06) Source: Regenstrief Institute

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Fully-Specified Name

Component
Cystine/Creatinine
Property
SRto
Time
Pt
System
Urine
Scale
Qn
Method

Additional Names

Short Name
Cystine/Creat Ur-sRto
Display Name
Cystine/Creatinine (U) [Molar ratio]
Consumer Name Alpha Get Info
Cystine/Creatinine, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0n
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
11422

Member of these Panels

LOINC Long Common Name
74991-1 Amino acids panel [Molar ratio] - Urine
90784-0 Cystinuria panel - Urine

Member of these Groups Get Info

LOINC Group Group Name
LG35282-9 Cystine/Creatinine|SRto|Urine

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Cystin im U/Krea
es-AR Spanish (Argentina) cistina/creatinina:relación de concentración de la sustancia:punto en el tiempo:orina:cuantitativo:
es-MX Spanish (Mexico) Cistina / Creatinina:Proporción de sustancia:Punto temporal:Orina:Cuantitativo:
es-ES Spanish (Spain) Cistina/Creatinina:Relacion de Sustancia:Punto temporal:Orina:Qn:
Synonyms: Cuantitativo
fr-CA French (Canada) Cystine/Créatinine:Ratio de substance:Temps ponctuel:Urine:Quantitatif:
fr-FR French (France) Cystine/créatinine:Moles ratio:Ponctuel:Urine:Numérique:
fr-BE French (Belgium) Cystine/Créatinine:Ratio de substance:Temps ponctuel:Urine:Quantitatif:
it-IT Italian (Italy) Cistina/Creatinina:Srto:Pt:Urine:Qn:
Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza
ko-KR Korean (Korea, Republic Of) 시스틴/크레아티닌:물질구성비:검사시점:뇨:정량:
nl-NL Dutch (Netherlands) cystine/creatinine:molaire verhouding:moment:urine:kwantitatief:
Synonyms: kreatinine
pt-BR Portuguese (Brazil) Cistina/Creatinina:SCrto:Pt:Urina:Qn:
Synonyms: Cys-Cys; Dicysteine; Creat; CR; sRto; Substance concentration ratio; Point in time; Random; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; Chemistry; UCr
ru-RU Russian (Russian Federation) Цистин/Креатинин:МольОтн:ТчкВрм:Моча:Колич:
Synonyms: Количественный Мольная доля;Молярная доля;Отношение концентраций Точка во времени;Момент
tr-TR Turkish (Turkey) Sistin/Kreatinin:SOrn:Zmlı:İdrar:Kant:
Synonyms: SubsOranı
zh-CN Chinese (China) 胱氨酸/肌酐:物质的量比率:时间点:尿液:定量型:
Synonyms: CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 Cys-Cys;双巯丙氨酸 UCr 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉 尿液肌酐 尿液肌酸酐 尿肌酸酐 时刻;随机;随意;瞬间 物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值 肌酸内酰胺

Example Units

Unit Source
mmol/mol eCHN
mmol/mol{creat} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=22687-8