Version 2.80

Part Descriptions

LP15747-6   Gentamicin
Gentamicin is an aminoglycoside antibiotic, which has a bactericidal mode of action binding to the ribosome and various ribozymes to inhibit protein synthesis. Gentamicin is a hydrophilic molecule and is considered to have limited capacity to penetrate eukaryotic cells. Administered intravenously or intramuscularly, gentamicin is used to treat many bacterial infections, particularly gram-negative organisms such as meningitis, and infections of the blood, abdomen, lungs, skin, bones, joints and urinary tract, and is often used to treat severe cases of tularemia and the plague. The effect of gentamicin is mediated through the production of reactive oxygen species (ROS), which causes destablization of iron-sulfur (Fe-S) clusters and generates toxic, bactericidal compounds through the Fenton reaction. Gentamicin may cause kidney, nerve and severe hearing problems. More common side effects include nausea, headache, fever, rash and hoarseness. PMID: 26503658 [MedlinePlus Drug:a682275] Source: Regenstrief LOINC

LP20176-1   trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Trough levels for therapeutic drug monitoring

Fully-Specified Name

Component
Gentamicin^trough
Property
SCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Long Common Name
Gentamicin [Moles/volume] in Serum or Plasma --trough
Short Name
Gentamicin Trough SerPl-sCnc
Display Name
Gentamicin trough [Moles/Vol]
Consumer Name Alpha Get Info
Gentamicin trough, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 1.0n
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
2366

Member of these Groups Get Info

LOINC Group Group Name
LG50413-0 Gentamicin^trough|Pt|Ser/Plas

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Gentamicin^TDM Tal:Stoffmengenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:
el-GR Greek (Greece) Γενταμυκίνη^ελάχιστα επίπεδα:SCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: SCnc
es-AR Spanish (Argentina) gentamicina^concentración mínima [valle]:concentración de sustancia:punto en el tiempo:suero/plasma:cuantitativo:
es-ES Spanish (Spain) Gentamicina^Valle monitorización terapéutica de fármacos:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Gentamicina ^ canal:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE Estonian (Estonia) Gentamütsiin^baas:SCnc:Pt:S/P:Qn:
Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA French (Canada) Gentamicine^Creux:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Gentamicine taux résiduel:Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Gentamicine^Creux:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: Minimum, nadir
it-IT Italian (Italy) Gentamicina^valore minimo:SCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Sostanza Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM
ko-KR Korean (Korea, Republic Of) 겐타마이신^최저 약물 농도 시간:물질농도:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) gentamicine^dalspiegel:mol/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Gentamicina^basal:SCnc:Pt:Sor/Plas:Qn:
Synonyms: c213; Gent; Garamycin; Genj; Genirr; Pre; Predose; Pre-dose; Substance concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU Russian (Russian Federation) Гентамицин^остаточная концентрация:МолКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный минимум концентрации Молярность;Молярная объёмная концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Gentamisin^en düşük:SubKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 庆大霉素^波谷:物质的量浓度:时间点:血清/血浆:定量型:
Synonyms: 一剂药物的初始剂量;初始剂量;剂量药物的初始剂量;前剂量;曲线上的最小值;最低点;本底剂量;治疗药物监测 - 波谷;预剂量 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 正泰霉素;艮他霉素 毒品 毒品类 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

Unit Source
umol/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=22747-0