Version 2.72

22826-2Influenza virus A identified in Specimen by BioassayActive

Term Description

Assesses the pathogenicity of virus strain by inoculation into young chickens and monitoring development of clinical signs and/or death.
Source: Regenstrief LOINC

Part Description

LP14239-5   Influenza virus A
Influenza viruses, from the family Orthomyxoviridae, are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C are medically relevant to humans. Aquatic birds harboring avian IAV are the likely natural reservoir for all known IAV subtypes and are probably the original source of all human pandemic IAV strains. IAV maintained in wild birds have been associated with stable host switch events to novel hosts, including most often to domestic poultry but also to horses, swine, toothed whales and humans. The influenza virus life cycle begins with the binding of viral HA to host cell receptors. Endocytosis and HA-mediated fusion of the viral and cellular membranes occurs. Viral ribonucleoprotein complexes are released into the cytoplasm, travel to the nucleus, then are replicated and transcribed by the viral polymerase complex. The new viruses are formed and bud when the newly formed ribonucleicprotein complexes and structural proteins reach the plasma membrane. Further research is needed to better understand how IAVs switch hosts and the viral genetic changes that underlie human adaptation. IAV causes respiratory infections in humans ranging from asymptomatic to fatal. Pandemics are attributed to "novel" viruses which possess a viral hemagglutinin (HA) to which humans do not have immunity. [PMID:20542248] [PMID:25812763]
Influenza viruses A and B are single-stranded RNA enveloped viruses belonging to the Orthomyxoviridae family. The symptoms of infection of Influenza A and B include fever, cough, sore throat, rhinorrhea, nasal congestion, headache, myalgia and malaise. Some patients may experience gastrointestinal symptoms including watery diarrhea, vomiting and abdominal pain. The influenza viruses spread rapidly in enclosed spaces with a documented rate of infection of 70% following a common source of exposure. Infection occurs in the respiratory epithelium in both the upper and lower respiratory tract, and the virus can be found in many specimen types, including nasal aspirates, nasal or nasopharyngeal swabs, throat swabs, sputum and tracheal aspirates. When infection rates reach epidemic proportions, hospitalization of children and elderly patients rises as does the mortality rates of elderly patients.(Manual of Clinical Microbiology, 11th edition, James H. Jorgensen; Karen C. Carroll; Guido Funke; Michael A Pfaller; Marie Louise Landry; Sandra S. Richter; David W. Warnock) Source: Regenstrief LOINC

Fully-Specified Name

Influenza virus A identified

Additional Names

Short Name
FLUAV Spec Bioassay
Display Name
FLUAV identified Bioassay Nom (Specimen)
Consumer Name Alpha
Influenza A (Flu A) test, Specimen

Basic Attributes

First Released
Version 1.0n
Last Updated
Version 2.69
Order vs. Observation

Member of these Groups

LG32757-3 Influenza virus

Language Variants Get Info

zh-CNChinese (China)
流感病毒 A 型 已鉴定的:存在与否或特征标识:时间点:XXX:名义型:生物鉴定
nl-NLDutch (Netherlands)
Influenzavirus A geïdentificeerd:identificator:moment:XXX:nominaal:bioassay
fr-BEFrench (Belgium)
Virus de l'influenza A Identifiées:Présence ou identité:Temps ponctuel:XXX:Nominal:Test biologique
fr-CAFrench (Canada)
Virus de l'influenza A , Identifiés:Présence ou identité:Temps ponctuel:XXX:Nominal:Test biologique
fr-FRFrench (France)
Influenza virus A identifié:Identification:Ponctuel:Milieux divers:Résultat nominal:Bio-essai
it-ITItalian (Italy)
Influenza A, virus , identificato:Prid:Pt:XXX:Nom:Saggio biologico
ko-KRKorean (Korea, Republic of)
A형 인플루엔자 바이러스 동정:존재:검사시점:XXX:명칭결과:생물학적 분석
pt-BRPortuguese (Brazil)
Identificação de Influenza vírus A:Ident:Pt:XXX:Nom:Bioensaio
es-ARSpanish (Argentina)
virus de la influenza aviaria identificado:presencia o identidad:punto en el tiempo:XXX:Nominal:bioanálisis
es-MXSpanish (Mexico)
Virus de la influenza A identificado:Presencia o identidad:Punto temporal:XXX:Nominal:Bioensayo
es-ESSpanish (Spain)
Virus Influenza A identificado:Presencia o identidad:Punto temporal:XXX:Nom:Bioensayo
tr-TRTurkish (Turkey)
İnfluenza virüsü A tanımlanmış:MevcKimlik:Zmlı:XXX:Snf:Biyoölçüm

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