Version 2.78

Part Description

LP14363-3   Hepatitis C virus NS5
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

Reference Information

Type Source Reference
Mapping Guidance Regenstrief Help Part of immune blot panel. Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations

Fully-Specified Name

Component
Hepatitis C virus NS5 Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IB

Additional Names

Short Name
HCV NS5 Ab Ser Ql IB
Display Name
HCV NS5 Ab IB Ql (S)
Consumer Name Alpha Get Info
Hepatitis C virus (HCV) NS5 antibody, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0n
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Observation
Common Test Rank Get Info
10985

Member of these Panels

LOINC Long Common Name
75887-0 HCV antibody RIBA tests - Meaningful Use set by Immunoblot

Member of these Groups Get Info

LOINC Group Group Name
LG32754-0 Hepatitis C virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Hepatitis-C-Virus NS5 Ak:Nachweis oder Schwellenwert:Zeitpunkt:Serum:Ordinal:Immunoblot
es-AR Spanish (Argentina) [anticuerpo anti - ] virus NS5 de la hepatitis C [Ac]:concentración arbitraria:punto en el tiempo:suero:ordinal:inmunotransferencia
es-ES Spanish (Spain) Virus de la Hepatitis C región NS5 Anticuerpos:PrThr:Punto temporal:Suero:Ord:Inmunoblot (IB)
es-MX Spanish (Mexico) Virus de la hepatitis C NS5 Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunotransferencia
et-EE Estonian (Estonia) C-hepatiidi viirus NS5 antikehad:PrThr:Pt:S:Ord:IB
Synonyms: Järgarvuline Juhuslik Seerum
fr-CA French (Canada) Virus de l'hépatite C NS5, Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoblot
fr-FR French (France) Hépatite C virus NS5 Ac:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoblot
fr-BE French (Belgium) Virus de l'hépatite C NS5 Ac:PrThr:Temps ponctuel:Sérum:Ordinal:Immunoblot
Synonyms: Anticorps HCV HCV NS5
it-IT Italian (Italy) Epatite C virus, NS5 Ab:PrThr:Pt:Siero:Ord:IB
Synonyms: anticorpo Immunoblot (IB) Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Virus dell''epatite C Virus dell''epatite C NS5
ko-KR Korean (Korea, Republic Of) C형 간염 바이러스 NS5 항체:임의농도:검사시점:혈청:순위척도:면역 탁본법
nl-NL Dutch (Netherlands) Hepatitis C-virus NS5 As:aanwezigheid:moment:serum:ordinaal:immunoblotting
Synonyms: antistof; antilichaam IB
pl-PL Polish (Poland) Wirus zapalenia wątroby typu C NS5 Ab:granica wykrywalności:punkt w czasie:surowica:półilościowy:immunoblotting
Synonyms: Przeciwciała do antygenu NS5 wirusa zapalenia wątroby typu C
pt-BR Portuguese (Brazil) Hepatite C vírus NS5 Ac:ACnc:Pt:Soro:Ord:Imunoblot
Synonyms: ; HCV NS5; Hep C; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Western blot; WB; Immune blot; Immunobl; Blt; WBLOT; West blt; West blot; RIBA; Immunoblot; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Hepatit; Hepatis; Microbiology
ru-RU Russian (Russian Federation) Гепатита С вирус NS5 Ат:PrThr:ТчкВрм:Сыв:Пор:ИБ
Synonyms: Антитело Иммуноблот (ИБ) Порядковый Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Hepatit C virüsü NS5 Ab:MevcEşik:Zmlı:Ser:Srl:IB
Synonyms: Ak Mevcut
zh-CN Chinese (China) 丙型肝炎病毒 NS5 抗体:存在情况或阈值:时间点:血清:序数型:免疫印迹法
Synonyms: Ab;自身抗体 C 型;丙;丙型 HCV NS5 Ab HCV NS5 抗体 HCV NS5;Hep C NS5;丙肝病毒 NS5;肝炎病毒 C 型 NS5 HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 Hep C NS5 Ab Hep C NS5 抗体 丙型肝炎病毒 NS5 Ab 丙肝病毒 NS5 Ab 丙肝病毒 NS5 抗体 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫印迹;西部印迹法;Immunoblot;immunoblotting;IB 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 肝 肝炎病毒 C 型 NS5 Ab 肝炎病毒 C 型 NS5 抗体

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=23871-7