Version 2.78

Part Descriptions

LP207365-0   Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP6416-4   Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

Fully-Specified Name

Component
Polio virus 1 Ab.Neut^1st specimen
Property
Titr
Time
Pt
System
Ser
Scale
SemiQn
Method
Neut

Additional Names

Short Name
PV1 NAb sp1 Titr Ser Nt
Display Name
Polio virus 1 neut ab spec 1 Neut test (S) [Titer]
Consumer Name Alpha Get Info
Polio virus 1 neutralizing antibody specimen 1, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0o
Last Updated
Version 2.75
Change Reason
Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG32765-6 Polio virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Polio-Virus 1 Ak.neutralisierend^1. Probenmaterial:Titer:Zeitpunkt:Serum:Semiquantitativ:Neutralisationstest
es-AR Spanish (Argentina) [anticuerpo anti - ] virus 1 de la poliomielitis [Ac]^primer espécimen:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:neutralización
es-ES Spanish (Spain) Polio virus 1 Anticuerpos antineutrófilos^1er especimen:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:Prueba de neutralización
Synonyms: Semicuantitativo
es-MX Spanish (Mexico) Virus de la poliomielitis 1 Ab^1er espécimen:Título:Punto temporal:Suero:Cuantitativo:Prueba de neutralización
fr-FR French (France) Polio virus 1 Ac neutralisant 1er prélèvement:Titre:Ponctuel:Sérum:Semi-Quantitatif:Neutralisation
fr-CA French (Canada) Poliovirus 1 Ac.neut^1er échantillon:Titre:Temps ponctuel:Sérum:SemiQn:Test de neutralisation
it-IT Italian (Italy) Polio virus 1 Ab.Neut^1° campione:Titr:Pt:Siero:SemiQn:Neut
Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Siero Test di neutralizzazione Titolo Virus poliomielitico Virus poliomielitico 1
ko-KR Korean (Korea, Republic Of) 폴리오 바이러스 1 항체^제1 검체:역가:검사시점:혈청:정량:중화
nl-NL Dutch (Netherlands) Poliovirus 1 As.neutraliserend^1ste monster:titer:moment:serum:semikwantitatief:neutralisatietest
Synonyms: antistof; antilichaam
pt-BR Portuguese (Brazil) Polio vírus 1 Ac^1ª amostra:Título:Pt:Soro:Qn:Teste de neutralização
Synonyms: ; PV1; Polio virus type I; Poliovirus; PV; sp1; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Nt; NT; Neutralization test; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Spec; Pre immunization; Acute specimen; First; Microbiology
zh-CN Chinese (China) 脊髓灰质炎病毒 1 型 抗体.中和^第1个标本:滴定度:时间点:血清:半定量型:中和试验
Synonyms: Ⅰ Ab;自身抗体 I PV 1 Ab PV 1 型 Ab PV 1 型抗体 PV 1 抗体 PV 1;PV 1 型;PV I;PV I 型;PV1;PVI;脊灰病毒 1 型;脊灰病毒 I 型;脊髓灰质炎病毒 I 型 PV I Ab PV I 型 Ab PV I 型抗体 PV I 抗体 PV;小儿麻痹症病毒;小儿麻痹病毒;脊灰病毒 PV1 Ab PV1 抗体 PVI Ab PVI 抗体 中和试验;中和抗体;中和 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 免疫之前 免疫之前的标本 免疫前 免疫前标本 受检物 在免疫之前 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 急性期 急性期标本 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 样品 样本 第1个标本（样本、样品、试样） 第一个标本 脊灰病毒 1 型 Ab 脊灰病毒 1 型抗体 脊灰病毒 I 型 Ab 脊灰病毒 I 型抗体 脊髓灰质炎病毒 1 型 Ab 脊髓灰质炎病毒 I 型 Ab 脊髓灰质炎病毒 I 型抗体 试样

Example Units

Unit Source
{titer} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=24169-5