24169-5

Polio virus 1 neutralizing antibody [Titer] in Serum by Neutralization test --1st specimen

Active

Part Descriptions

LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Polio virus 1 Ab.Neut^1st specimen:Titr:Pt:Ser:SemiQn:Neut
Long Common Name: Polio virus 1 neutralizing antibody [Titer] in Serum by Neutralization test --1st specimen
Short Name: PV1 NAb sp1 Titr Ser Nt
Display Name: Polio virus 1 neut ab spec 1 Neut test (S) [Titer]
Consumer Name Alpha Get Info: Polio virus 1 neutralizing antibody specimen 1, Blood

Part Model Get Info

Component
Polio virus 1 Ab.Neut^1st specimen
LP430445-9
- Analyte
  Polio virus 1 Ab.Neut
  LP430444-2
  - Component Numerator
    Polio virus 1 Ab.Neut
    LP430444-2
    - Component Numerator Core
      Polio virus 1
      LP14058-9
    - Component Numerator Core Suffix
      Ab.Neut
      LP207365-0
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  1st specimen
  LP20166-2
- Adjustment
  NULL
- Count
  NULL
Property
Titr
LP6881-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
SemiQn
LP436123-6
Method
Neut
LP6416-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 1.0o
Last Updated: Version 2.75 (MAJ)
Change Reason: Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG32765-6	Polio virus

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Poliovirus Ab.neutralizační^Vzorek 1:Arbitrární koncentrace (titr):Časový bod:Sérum:Semikvantitativní:Neutralizační test
de-DE	German (Germany)	Polio-Virus 1 Ak.neutralisierend^1. Probenmaterial:Titer:Zeitpunkt:Serum:Semiquantitativ:Neutralisationstest
el-GR	Greek (Greece)	Ιός πολιομυελίτιδας 1 Ab.Neut^1ο δείγμα:Titr:Pt:Ορός:Ημιποσοτική:Ουδετερόφιλα Synonyms: 1ο δείγμα Ab.Neut MICRO Pt Titr Αντίσωμα Ημιποσοτική Ιός Ιός πολιομυελίτιδας Ιός πολιομυελίτιδας 1 Ορός Ουδετερόφιλα
es-AR	Spanish (Argentina)	[anticuerpo anti - ] virus 1 de la poliomielitis [Ac]^primer espécimen:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:neutralización
es-ES	Spanish (Spain)	Polio virus 1 Anticuerpos antineutrófilos^1er especimen:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:Prueba de neutralización Synonyms: Semicuantitativo
es-MX	Spanish (Mexico)	Virus de la poliomielitis 1 Ab^1er espécimen:Título:Punto temporal:Suero:Cuantitativo:Prueba de neutralización
fr-FR	French (France)	Polio virus 1 Ac neutralisant^1er prélèvement:Titre:Ponctuel:Sérum:Semi-Quantitatif:Neutralisation
fr-CA	French (Canada)	Poliovirus 1 Ac.neut^1er échantillon:Titre:Temps ponctuel:Sérum:SemiQn:Test de neutralisation
it-IT	Italian (Italy)	Polio virus 1 Ab.Neut^1° campione:Titr:Pt:Siero:SemiQn:Neut Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Siero Test di neutralizzazione Titolo Virus poliomielitico Virus poliomielitico 1
ko-KR	Korean (Korea, Republic Of)	폴리오 바이러스 1 항체^제1 검체:역가:검사시점:혈청:정량:중화
nl-NL	Dutch (Netherlands)	Poliovirus 1 As.neutraliserend^1ste monster:titer:moment:serum:semikwantitatief:neutralisatietest Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Wirus polio typ 1 Ab.Neutralizujące^1 próbka:miano:punkt w czasie:surowica:półilościowy:test neutralizacji Synonyms: pierwsza próbka Przeciwciała do wirusa polio typu 1 Przeciwciała neutralizujące do wirusa polio typu 1 Przeciwciała neutralizujące do wirusa polio typu 1 próbka pierwsza
pt-BR	Portuguese (Brazil)	Polio vírus 1 Ac^1ª amostra:Título:Pt:Soro:Qn:Teste de neutralização Synonyms: ; PV1; Polio virus type I; Poliovirus; PV; sp1; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Nt; NT; Neutralization test; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Spec; Pre immunization; Acute specimen; First; Microbiology
zh-CN	Chinese (China)	脊髓灰质炎病毒 1 型抗体.中和^第1个标本:滴定度:时间点:血清:半定量型:中和试验 Synonyms: Ⅰ Ab;自身抗体 I PV 1 Ab PV 1 型 Ab PV 1 型抗体 PV 1 抗体 PV 1;PV 1 型;PV I;PV I 型;PV1;PVI;脊灰病毒 1 型;脊灰病毒 I 型;脊髓灰质炎病毒 I 型 PV I Ab PV I 型 Ab PV I 型抗体 PV I 抗体 PV;小儿麻痹症病毒;小儿麻痹病毒;脊灰病毒 PV1 Ab PV1 抗体 PVI Ab PVI 抗体中和试验;中和抗体;中和传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体免疫之前免疫之前的标本免疫前免疫前标本受检物在免疫之前微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）急性期急性期标本效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数时刻;随机;随意;瞬间标本（样本、样品、试样）样品样本第1个标本（样本、样品、试样）第一个标本脊灰病毒 1 型 Ab 脊灰病毒 1 型抗体脊灰病毒 I 型 Ab 脊灰病毒 I 型抗体脊髓灰质炎病毒 1 型 Ab 脊髓灰质炎病毒 I 型 Ab 脊髓灰质炎病毒 I 型抗体试样

Example Units

Unit	Source
{titer}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.