24383-2
Intrinsic factor Ab [Presence] in Serum by Immunoassay
Active
Part Descriptions
LP15673-4 Intrinsic factor
Intrinsic factor is a glycoprotein produced by the parietal cells of the stomach. It is necessary for the absorption of vitamin B12 later on in the small intestine. Upon entry into the stomach, vitamin B12 becomes bound to one of two B12 binding proteins present in gastric juice. In the less acidic environment of the small intestine, these proteins dissociate from the vitamin, enabling it to bind to intrinsic factor and enter the portal circulation through a receptor in the ileal mucosa specific for the B12 -intrinsic factor complex. In pernicious anemia, an autoimmune disease, autoantibodies directed against intrinsic factor or parietal cells themselves lead to an intrinsic factor deficiency, malabsorption of vitamin B12, and subsequent megaloblastic anemia. Atrophic gastritis can also cause intrinsic factor deficiency and anemia through damage to the parietal cells of the stomach wall.
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Source: Wikipedia, intrinsic factor (Wikipedia)
LP15673-4 Intrinsic factor
A glycoprotein secreted by the cells of the gastric glands that is required for the absorption of VITAMIN B 12. Deficiency of intrinsic factor results in ANEMIA, PERNICIOUS.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- Intrinsic factor Ab
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- IA
Additional Names
- Short Name
- IF Ab Ser Ql IA
- Display Name
- Intrinsic factor Ab IA Ql (S)
- Consumer Name Alpha Get Info
- Intrinsic factor antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 1.0o
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG8731-4 | Intrinsic factor Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Intrinsic Factor Ak: |
de-AT | German (Austria) | Synonyms: Intrinsic-Faktor-AK ql. IA |
es-ES | Spanish (Spain) | Factor intrínseco Anticuerpos: |
es-MX | Spanish (Mexico) | Factor intrínseco Ab: |
es-AR | Spanish (Argentina) | [anticuerpo anti - ] factor intrínsico [Ac]: |
et-EE | Estonian (Estonia) | Sisemine faktor antikehad: Synonyms: Järgarvuline Juhuslik Seerum |
fr-CA | French (Canada) | Facteur intrinsèque, Ac: |
fr-FR | French (France) | Facteur intrinsèque anticorps: |
fr-BE | French (Belgium) | Facteur intrinsèque Ac: Synonyms: Anticorps FI |
it-IT | Italian (Italy) | Fattore intrinseco Ab: Synonyms: anticorpo Immunoassay Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
ko-KR | Korean (Korea, Republic Of) | 내재 인자 항체: |
nl-NL | Dutch (Netherlands) | intrinsieke factor As: Synonyms: antistof; |
pl-PL | Polish (Poland) | Czynnik wewnętrzny Ab: Synonyms: Przeciwciała do czynnika wewnętrznego Castle''a |
pt-BR | Portuguese (Brazil) | Fator intrínseco Ac: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Внутренний фактор Ат: Synonyms: Антитело Порядковый Сыворотка Точка во времени; |
tr-TR | Turkish (Turkey) | İntrinsik faktör Ab: Synonyms: Ak İmmünölçüm, immünoassay Mevcut |
zh-CN | Chinese (China) | 内因子 抗体: Synonyms: Ab; |
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