2488-5
Intrinsic factor [Mass/volume] in Serum
Discouraged
Status Information
- Status
- DISCOURAGED
- Comment
- No units are associated with this term - cannot verify validity
Part Descriptions
LP15673-4 Intrinsic factor
Intrinsic factor is a glycoprotein produced by the parietal cells of the stomach. It is necessary for the absorption of vitamin B12 later on in the small intestine. Upon entry into the stomach, vitamin B12 becomes bound to one of two B12 binding proteins present in gastric juice. In the less acidic environment of the small intestine, these proteins dissociate from the vitamin, enabling it to bind to intrinsic factor and enter the portal circulation through a receptor in the ileal mucosa specific for the B12 -intrinsic factor complex. In pernicious anemia, an autoimmune disease, autoantibodies directed against intrinsic factor or parietal cells themselves lead to an intrinsic factor deficiency, malabsorption of vitamin B12, and subsequent megaloblastic anemia. Atrophic gastritis can also cause intrinsic factor deficiency and anemia through damage to the parietal cells of the stomach wall.
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Source: Wikipedia, intrinsic factor (Wikipedia)
LP15673-4 Intrinsic factor
A glycoprotein secreted by the cells of the gastric glands that is required for the absorption of VITAMIN B 12. Deficiency of intrinsic factor results in ANEMIA, PERNICIOUS.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- Intrinsic factor
- Property
- MCnc
- Time
- Pt
- System
- Ser
- Scale
- Qn
- Method
Additional Names
- Short Name
- IF Ser-mCnc
- Display Name
- Intrinsic factor (S) [Mass/Vol]
- Consumer Name Alpha Get Info
- Intrinsic factor, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.44
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-AR | Spanish (Argentina) | factor intrínseco: |
es-ES | Spanish (Spain) | Factor intrínseco: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Factor intrínseco: |
et-EE | Estonian (Estonia) | Sisemine faktor: Synonyms: Juhuslik Kvantitatiivne Seerum |
fr-CA | French (Canada) | Facteur intrinsèque: |
fr-BE | French (Belgium) | Facteur intrinsèque: Synonyms: FI |
it-IT | Italian (Italy) | Fattore intrinseco: Synonyms: Chimica Concentrazione di Massa Punto nel tempo (episodio) Siero |
ko-KR | Korean (Korea, Republic Of) | 내재 인자: |
nl-NL | Dutch (Netherlands) | intrinsieke factor: |
pl-PL | Polish (Poland) | Czynnik wewnętrzny: |
pt-BR | Portuguese (Brazil) | Fator intrínseco: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Внутренний фактор: Synonyms: Количественный Массовая концентрация Сыворотка Точка во времени; |
tr-TR | Turkish (Turkey) | İntrinsik faktör: |
zh-CN | Chinese (China) | 内因子: Synonyms: IF; |
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