Version 2.78

Status Information

Status
DISCOURAGED
Comment
No units are associated with this term - cannot verify validity

Part Descriptions

LP15673-4   Intrinsic factor
Intrinsic factor is a glycoprotein produced by the parietal cells of the stomach. It is necessary for the absorption of vitamin B12 later on in the small intestine. Upon entry into the stomach, vitamin B12 becomes bound to one of two B12 binding proteins present in gastric juice. In the less acidic environment of the small intestine, these proteins dissociate from the vitamin, enabling it to bind to intrinsic factor and enter the portal circulation through a receptor in the ileal mucosa specific for the B12 -intrinsic factor complex. In pernicious anemia, an autoimmune disease, autoantibodies directed against intrinsic factor or parietal cells themselves lead to an intrinsic factor deficiency, malabsorption of vitamin B12, and subsequent megaloblastic anemia. Atrophic gastritis can also cause intrinsic factor deficiency and anemia through damage to the parietal cells of the stomach wall. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, intrinsic factor (Wikipedia)

LP15673-4   Intrinsic factor
A glycoprotein secreted by the cells of the gastric glands that is required for the absorption of VITAMIN B 12. Deficiency of intrinsic factor results in ANEMIA, PERNICIOUS. Source: National Library of Medicine, MeSH 2006

Fully-Specified Name

Component
Intrinsic factor
Property
MCnc
Time
Pt
System
Ser
Scale
Qn
Method

Additional Names

Short Name
IF Ser-mCnc
Display Name
Intrinsic factor (S) [Mass/Vol]
Consumer Name Alpha Get Info
Intrinsic factor, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.44
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) factor intrínseco:concentración de masa:punto en el tiempo:suero:cuantitativo:
es-ES Spanish (Spain) Factor intrínseco:Concentración de masa:Punto temporal:Suero:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Factor intrínseco:Concentración de masa:Punto temporal:Suero:Cuantitativo:
et-EE Estonian (Estonia) Sisemine faktor:MCnc:Pt:S:Qn:
Synonyms: Juhuslik Kvantitatiivne Seerum
fr-CA French (Canada) Facteur intrinsèque:Concentration de masse:Temps ponctuel:Sérum:Quantitatif:
fr-BE French (Belgium) Facteur intrinsèque:Concentration de masse:Temps ponctuel:Sérum:Quantitatif:
Synonyms: FI
it-IT Italian (Italy) Fattore intrinseco:MCnc:Pt:Siero:Qn:
Synonyms: Chimica Concentrazione di Massa Punto nel tempo (episodio) Siero
ko-KR Korean (Korea, Republic Of) 내재 인자:질량농도:검사시점:혈청:정량:
nl-NL Dutch (Netherlands) intrinsieke factor:massa/volume:moment:serum:kwantitatief:
pl-PL Polish (Poland) Czynnik wewnętrzny:stężenie masowe:punkt w czasie:surowica:ilościowy:
pt-BR Portuguese (Brazil) Fator intrínseco:MCnc:Pt:Soro:Qn:
Synonyms: ; IF; Acsorbing intrinsic; Mass concentration; Level; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Fac; Fact; Chemistry
ru-RU Russian (Russian Federation) Внутренний фактор:МассКонц:ТчкВрм:Сыв:Колич:
Synonyms: Количественный Массовая концентрация Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) İntrinsik faktör:KütlKons:Zmlı:Ser:Kant:
zh-CN Chinese (China) 内因子:质量浓度:时间点:血清:定量型:
Synonyms: IF;内因子(Intrinsic Factor,IF);内因素;内在因素;吸附性内(Absorbing intrinsic) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 因素 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积) 系数

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