Version 2.77

Part Descriptions

LP17184-0   17-Hydroxypregnenolone
17-Hydroxypregnenolone (also 17-OH-pregnenolone and 17-alpha-hydroxypregnenolone), is a C21 steroid that is obtained by hydroxylation of pregnenolone at the C17-alpha position. This step is performed by the mitochondrial cytochrome P450 enzyme 17-hydroxylase (CYP17A1) that is present in the adrenal and gonads. Peak levels are reached in humans at the end of puberty and then decline. High levels are also achieved during pregnancy.
Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent. Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, 17-hydroxypregnenolone (Wikipedia)

LP17184-0   17-Hydroxypregnenolone
17-Hydroxypregnenolone, also known as 17-OH-PG, is a steroid hormone that is derived from cholesterol. 17-OH-PG is involved in the synthesis of cortisol, aldosterone and androstenedione in the adrenal glands. 17-OH-PG levels are measured to screen for congenital adrenal hyperplasia (CAH), a group of inherited disorders of the adrenal gland. High levels of 17-OH-PG in the blood indicate cortisol and aldosterone are not being produced in normal levels. PMID: 20077078 [Lab Tests Online:6-17hydroxy/tab/sample] Source: Regenstrief LOINC

Fully-Specified Name

Component
17-Hydroxypregnenolone
Property
SCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
17OH-Preg SerPl-sCnc
Display Name
17-Hydroxypregnenolone [Moles/Vol]
Consumer Name Alpha Get Info
17-Hydroxypregnenolone, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.00
Last Updated
Version 2.40
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
79221-8 Steroid fractions panel - Serum or Plasma

Member of these Groups Get Info

LOINC Group Group Name
LG41941-2 17-Hydroxypregnenolone|Pt|Ser/Plas

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) 17-Hydroxypregnenolon:Stoffmengenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:
es-MX Spanish (Mexico) 17-hidroxipregnenolona:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:
es-AR Spanish (Argentina) 17-hidroxipregnenolona:concentración de sustancia:punto en el tiempo:suero:cuantitativo:
es-ES Spanish (Spain) 17-Hidroxipregnenolona:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
et-EE Estonian (Estonia) 17-hüdroksüpregnenoloon:SCnc:Pt:S/P:Qn:
Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA French (Canada) 17-hydroxyprégnénolone:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) 17-hydroxyprégnénolone:Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) 17-hydroxyprégnénolone:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT Italian (Italy) 17-Idrossipregnenolone:SCnc:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR Korean (Korea, Republic Of) 17-하이드록시프레그네놀론:물질농도:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) 17-hydroxypregnenolon:mol/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) 17-hidroxipregnenolona:SCnc:Pt:Sor/Plas:Qn:
Synonyms: ; 17OH-Preg; 17 hydroxy pregnenolone; 17-alpha-Hydroxypregnenolone; Substance concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Chemistry
ru-RU Russian (Russian Federation) 17-Гидроксипрегненолон:МолКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Молярность;Молярная объёмная концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) 17-Hidroksipregnenolon:SubKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 17-羟基孕烯醇酮:物质的量浓度:时间点:血清/血浆:定量型:
Synonyms: 17-Alpha-羟基娠烯醇酮;17-Alpha-羟基孕 5 烯 3β醇 20 酮;17-Alpha-羟基孕烯诺龙;17-Alpha-羟基孕烯醇酮;17-Alpha-羟基孕甾烯醇酮;17OH-Preg;17-α-羟基娠烯醇酮;17-α-羟基孕 5 烯 3β醇 20 酮;17-α-羟基孕烯诺龙;17-α-羟基孕烯醇酮;17-α-羟基孕甾烯醇酮;17-羟基娠烯醇酮;17-羟基孕 5 烯 3β醇 20 酮;17-羟基孕烯诺龙;17-羟基孕甾烯醇酮;17-羟娠烯醇酮;17-羟孕 5 烯 3β醇 20 酮 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 血清或血浆

Example Units

Unit Source
nmol/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=25316-1