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Status Information

Status
DISCOURAGED
Comment
Because there is a 3-fold difference in normal range between L>P and P>L methods, the use of the methodless term is not recommended.
Map-ToLong Common NameMapping Guidance
14804-9Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
14805-6Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Pyruvate to lactate reaction

Part Descriptions

LP15033-1   Lactate dehydrogenase
Lactate dehydrogenase (LDH) is an enzyme (EC 1.1.1.27) present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. As it can also catalyze the oxidation of hydroxybutyrate, it is occasionally called hydroxybutyrate dehydrogenase (HBD). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, D-lactate (Wikipedia)

LP15033-1   Lactate dehydrogenase
Lactate dehydrogenase (LDH, or also called LD) is an oxidoreductase (LD: EC 1.1.1.27) and is the most important clinically of several dehydrogenases occurring in human serum. LDH catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD. When disease, injury, or toxic material damages tissues, cells release LDH into the bloodstream. Since LDH is a fairly stable enzyme, it has been widely used to evaluate the presence of damage and toxicity of tissue and cells. LDH is cytoplasmic in its cellular location and in any one tissue is composed of one or two of five possible isoenzymes. While many of its clinical applications involve quantification of one or more specific serum isoenzymes, an estimate of total LDH is usually required. Lactate dehydrogenase catalyzes the reversible reaction: L-lactate + NAD <--> pyruvate + NADH. Testing methods either measure the increase in NADH produced in the lactate-to-pyruvate reaction or the decrease in NADH produced in the pyruvate-to-lactate reaction. PMID: 3882046. Reference ranges are highly method dependent. The pyruvate-to-lactate reaction is preferred theoretically because the equilibrium constant is large and the rate for any amount of enzyme is 2-3 times faster, thus smaller sample and shorter observation periods are needed. Disadvantages of the pyruvate-to-lactate reaction are loss of linearity as compared with the lactate-to-pyruvate reaction, and greater substrate inhibition of the enzyme. [Tietz Fourth Edition] Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Lactate dehydrogenase:CCnc:Pt:Ser/Plas:Qn:
Long Common Name
Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma
Short Name
LDH SerPl-cCnc
Display Name
LDH [Catalytic activity/Vol]
Consumer Name Alpha Get Info
Lactate Dehydrogenase (LDH), Blood

Part Model Get Info

  • Component
    Lactate dehydrogenase
    LP15033-1
    • Analyte
      Lactate dehydrogenase
      LP15033-1
      • Component Numerator
        Lactate dehydrogenase
        LP15033-1
        • Component Numerator Core
          Lactate dehydrogenase
          LP15033-1
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    CCnc
    LP6789-4
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
238

Member of these Panels

LOINCLong Common Name
42929-0Lactate dehydrogenase panel - Serum or Plasma

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Laktátdehydrogenáza:Katalytická koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
de-ATGerman (Austria)Synonyms: LDH
de-DEGerman (Germany)Lactatdehydrogenase:Katalytische Konzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:
Synonyms: LDH
el-GRGreek (Greece)Γαλακτική αφυδρογονάση:CCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: CCnc CHEM Pt Qn Γαλακτική αφυδρογονάση Γαλακτικό οξύ Ορός Ορός/Πλάσμα Πλάσμα
es-ARSpanish (Argentina)lactato deshidrogenasa:concentración catalítica:punto en el tiempo:suero/plasma:cuantitativo:
es-ESSpanish (Spain)Lactato deshidrogenasa:Concentración Catalítica:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Lactato deshidrogenasa:Concentración catalítica:Punto temporal:Suero o Plasma:Cuantitativo:
et-EEEstonian (Estonia)Laktaadi dehüdrogenaas:CCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CAFrench (Canada)Lactate déshydrogénase:Concentration catalytique:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FRFrench (France)Lactate déshydrogénase:Catalytique/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BEFrench (Belgium)Lactate déshydrogénase:Concentration catalytique:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: LDH
it-ITItalian (Italy)Lattato deidrogenasi:CCnC:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione Catalitica Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KRKorean (Korea, Republic Of)젖산 탈수소효소:촉매농도:검사시점:혈청/혈장:정량:
nl-NLDutch (Netherlands)lactaatdehydrogenase:enzymatische activiteit/volume:moment:serum of plasma:kwantitatief:
pl-PLPolish (Poland)Dehydrogenaza mleczanowa:stężenie katalityczne:punkt w czasie:surowica lub osocze:ilościowy:
pt-BRPortuguese (Brazil)Desidrogenase Láctica:CCnc:Pt:Sor/Plas:Qn:
Synonyms: ; LDH; L.D.H; Lactic acid dehydrogenase; LD; L-lactate dehydrogenase; Lact; 2-hydroxy-propionic acid; 2-hydroxy-propionate; Catalytic Concentration; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Dehydrog; Dehyrdogenase; Chemistry
ru-RURussian (Russian Federation)Лактатдегидрогеназа:КаталКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Каталитическая концентрация Количественный Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TRTurkish (Turkey)Laktat dehidrojenaz:KtlKons:Zmlı:Ser/Plaz:Kant:
uk-UAUkrainian (Ukraine)Лактатдегідрогеназа:Каталітична Концентрація:МоментЧасу:Сироватка/Плазма:Кількісно:
Synonyms: 2-Hydroxypropanoic acid; 2-hydroxy-propionate; 2-hydroxy-propionic acid; Catalytic Concentration; Chemistry; Dehydrog; Dehyrdogenase; L.D.H; Lact; Lactic acid; Lactic acid dehydrogenase; LD; LDH; L-lactate; L-lactate dehydrogenase; Pl; Plasma; Plsm; Point in time; QNT; Quan; Quant; Quantitative; Random; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR; Tumor marker
zh-CNChinese (China)乳酸脱氢酶:催化浓度:时间点:血清/血浆:定量型:
Synonyms: 2-羟基-丙酸;Lact;L-乳酸 L.D.H;LD;LDH;L-乳酸脱氢酶 催化浓度(单位体积);单位体积内酶的单位数 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 去氢酶 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 血清或血浆

Example Units

UnitSource
U/LExample UCUM Units
U/LeCHN
units/LREGENSTRIEF

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=2532-0