267-5
Gentamicin [Susceptibility] by Minimum inhibitory concentration (MIC)
Active
Part Description
LP15747-6 Gentamicin
Gentamicin is an aminoglycoside antibiotic, which has a bactericidal mode of action binding to the ribosome and various ribozymes to inhibit protein synthesis. Gentamicin is a hydrophilic molecule and is considered to have limited capacity to penetrate eukaryotic cells. Administered intravenously or intramuscularly, gentamicin is used to treat many bacterial infections, particularly gram-negative organisms such as meningitis, and infections of the blood, abdomen, lungs, skin, bones, joints and urinary tract, and is often used to treat severe cases of tularemia and the plague. The effect of gentamicin is mediated through the production of reactive oxygen species (ROS), which causes destablization of iron-sulfur (Fe-S) clusters and generates toxic, bactericidal compounds through the Fenton reaction. Gentamicin may cause kidney, nerve and severe hearing problems. More common side effects include nausea, headache, fever, rash and hoarseness. PMID: 26503658 [MedlinePlus Drug:a682275]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Gentamicin
- Property
- Susc
- Time
- Pt
- System
- Isolate
- Scale
- OrdQn
- Method
- MIC
Additional Names
- Short Name
- Gentamicin Islt MIC
- Display Name
- Gentamicin MIC [Susc]
- Consumer Name Alpha Get Info
- Susceptibility to Gentamicin
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 561
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 50545-3 | Bacterial susceptibility panel by Minimum inhibitory concentration (MIC) |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG41057-7 | GentamicinSusc| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Gentamicin: |
| es-AR | Spanish (Argentina) | gentamicina: |
| es-ES | Spanish (Spain) | Gentamicina: |
| es-MX | Spanish (Mexico) | Gentamicina: |
| et-EE | Estonian (Estonia) | Gentamütsiin: Synonyms: Isolaat Juhuslik Minimaalne inhibeeriv kontsentratsioon Tundlikkus |
| fr-CA | French (Canada) | Gentamicine: |
| fr-FR | French (France) | Gentamicine: |
| fr-BE | French (Belgium) | Gentamicine: |
| it-IT | Italian (Italy) | Gentamicina: Synonyms: Concentrazione minima inibitoria Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici |
| ko-KR | Korean (Korea, Republic Of) | 겐타마이신: |
| nl-NL | Dutch (Netherlands) | gentamicine: Synonyms: MIC |
| pt-BR | Portuguese (Brazil) | Gentamicina: Synonyms: c213; |
| ru-RU | Russian (Russian Federation) | Гентамицин: Synonyms: Минимальная ингибирующая концентрация (МИК) Порядковый или Количественный Точка во времени; |
| tr-TR | Turkish (Turkey) | Gentamisin: |
| zh-CN | Chinese (China) | 庆大霉素: Synonyms: 分离物; |
Example Units
| Unit | Source |
|---|---|
| mcg/mL | REGENSTRIEF |
| ug/mL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=267-5
LOINC Copyright
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