267-5

Gentamicin [Susceptibility] by Minimum inhibitory concentration (MIC)

Active

Part Description

LP15747-6 Gentamicin
Gentamicin is an aminoglycoside antibiotic, which has a bactericidal mode of action binding to the ribosome and various ribozymes to inhibit protein synthesis. Gentamicin is a hydrophilic molecule and is considered to have limited capacity to penetrate eukaryotic cells. Administered intravenously or intramuscularly, gentamicin is used to treat many bacterial infections, particularly gram-negative organisms such as meningitis, and infections of the blood, abdomen, lungs, skin, bones, joints and urinary tract, and is often used to treat severe cases of tularemia and the plague. The effect of gentamicin is mediated through the production of reactive oxygen species (ROS), which causes destablization of iron-sulfur (Fe-S) clusters and generates toxic, bactericidal compounds through the Fenton reaction. Gentamicin may cause kidney, nerve and severe hearing problems. More common side effects include nausea, headache, fever, rash and hoarseness. PMID: 26503658 [MedlinePlus Drug:a682275] Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Gentamicin:Susc:Pt:Isolate:OrdQn:MIC
Long Common Name: Gentamicin [Susceptibility] by Minimum inhibitory concentration (MIC)
Short Name: Gentamicin Islt MIC
Display Name: Gentamicin MIC [Susc]
Consumer Name Alpha Get Info: Susceptibility to Gentamicin

Part Model Get Info

Component
Gentamicin
LP15747-6
- Analyte
  Gentamicin
  LP15747-6
  - Component Numerator
    Gentamicin
    LP15747-6
    - Component Numerator Core
      Gentamicin
      LP15747-6
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Susc
LP6870-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Isolate
LP7370-2
- System Core
  Isolate
  LP7370-2
- Super System
  NULL
Scale
OrdQn
LP7752-1
Method
MIC
LP6389-3

Basic Attributes

Class: ABXBACT
Type: Laboratory
First Released: Version 1.0
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Observation
Common Test Rank Get Info: 561

Member of these Panels

LOINC	Long Common Name
50545-3	Bacterial susceptibility panel by Minimum inhibitory concentration (MIC)

Member of these Groups Get Info

LOINC Group	Group Name
LG41057-7	GentamicinSusc\|Isolate

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Gentamicin:Citlivost (mikroorganismy):Časový bod:Izolát:Ordinální nebo kvantitativní:Minimální inhibiční koncentrace (MIC)
de-DE	German (Germany)	Gentamicin:Empfindlichkeit (Mikroorganismen):Zeitpunkt:Isolat:Ordinal oder Quantitativ:Minimale Hemmkonzentration (MHK)
el-GR	Greek (Greece)	Γενταμυκίνη:Susc:Pt:Απομονωμένο στέλεχος:OrdQn:MIC Synonyms: ABXBACT MIC OrdQn Pt Susc Απομονωμένο στέλεχος Γενταμυκίνη
es-AR	Spanish (Argentina)	gentamicina:susceptibilidad:punto en el tiempo:cepa clínica:ordinal o cuantitativo:concentración inhibitoria mínima
es-ES	Spanish (Spain)	Gentamicina:Susceptibilidad:Punto temporal:Aislado:Ordinal Cuantitativo:Concentración mínima inhibitoria (CMI)
es-MX	Spanish (Mexico)	Gentamicina:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal Cuantitativo:Concentración mínima inhibitoria (MIC)
et-EE	Estonian (Estonia)	Gentamütsiin:Susc:Pt:Is:OrdQn:MIK Synonyms: Isolaat Juhuslik Minimaalne inhibeeriv kontsentratsioon Tundlikkus
fr-CA	French (Canada)	Gentamicine:Susceptibilité:Temps ponctuel:Isolat:Quantitatif ou ordinal:CMI
fr-FR	French (France)	Gentamicine:Sensibilité:Ponctuel:Isolat:Alphanumérique:CMI
fr-BE	French (Belgium)	Gentamicine:Susceptibilité:Temps ponctuel:Isolat:Quantitatif ou ordinal:CMI
it-IT	Italian (Italy)	Gentamicina:Susc:Pt:Isolato:OrdQn:MIC Synonyms: Concentrazione minima inibitoria Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici
ko-KR	Korean (Korea, Republic Of)	겐타마이신:감수성:검사시점:분리주:정량 or 순위척도:억제최소농도
nl-NL	Dutch (Netherlands)	gentamicine:gevoeligheid:moment:isolaat:ordinaal-kwantitatief:minimaal inhiberende concentratie Synonyms: MIC
pl-PL	Polish (Poland)	Gentamycyna:wrażliwość:punkt w czasie:izolat:uporządkowany ilościowy:minimalne stężenie hamujące Synonyms: wrażliwość (mikroorganizmów)
pt-BR	Portuguese (Brazil)	Gentamicina:Susc:Pt:Isolado:OrdQn:Concentração inibitória mínima Synonyms: c213; Gent; Garamycin; Genj; Genirr; Susceptibility; Susceptibilty; Sus; Suscept; Susceptibilities; Point in time; Random; Islt; Isol; Minimum inhibitory concentration; ANTIBIOTIC SUSCEPTIBILITIES
ru-RU	Russian (Russian Federation)	Гентамицин:Чув:ТчкВрм:Изолят:ПорКол:МИК Synonyms: Минимальная ингибирующая концентрация (МИК) Порядковый или Количественный Точка во времени;Момент Чувствительность (микроорганизмов)
tr-TR	Turkish (Turkey)	Gentamisin:Duyr:Zmlı:İzolat:SrlKant:MIC
zh-CN	Chinese (China)	庆大霉素:抗生素敏感性:时间点:分离株:定量型或序数型:最小抑菌浓度法 Synonyms: 分离物;分离菌;分离菌株;隔离种群抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类时刻;随机;随意;瞬间最低抑制浓度;最低抑制浓度法;最低抑菌浓度;最低抑菌浓度法;最小抑制浓度;最小抑制浓度法;最小抑菌浓度;Minimum Inhibitory Concentration;MIC 正泰霉素;艮他霉素

Example Units

Unit	Source
mcg/mL	REGENSTRIEF
ug/mL	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=267-5

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.