268-3

Gentamicin [Susceptibility] by Disk diffusion (KB)

Active

Part Description

LP15747-6 Gentamicin
Gentamicin is an aminoglycoside antibiotic, which has a bactericidal mode of action binding to the ribosome and various ribozymes to inhibit protein synthesis. Gentamicin is a hydrophilic molecule and is considered to have limited capacity to penetrate eukaryotic cells. Administered intravenously or intramuscularly, gentamicin is used to treat many bacterial infections, particularly gram-negative organisms such as meningitis, and infections of the blood, abdomen, lungs, skin, bones, joints and urinary tract, and is often used to treat severe cases of tularemia and the plague. The effect of gentamicin is mediated through the production of reactive oxygen species (ROS), which causes destablization of iron-sulfur (Fe-S) clusters and generates toxic, bactericidal compounds through the Fenton reaction. Gentamicin may cause kidney, nerve and severe hearing problems. More common side effects include nausea, headache, fever, rash and hoarseness. PMID: 26503658 [MedlinePlus Drug:a682275] Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Gentamicin:Susc:Pt:Isolate:OrdQn:Agar diffusion
Long Common Name: Gentamicin [Susceptibility] by Disk diffusion (KB)
Short Name: Gentamicin Islt KB
Display Name: Gentamicin Disk diffusion (KB) [Susc]
Consumer Name Alpha Get Info: Susceptibility to Gentamicin

Part Model Get Info

Component
Gentamicin
LP15747-6
- Analyte
  Gentamicin
  LP15747-6
  - Component Numerator
    Gentamicin
    LP15747-6
    - Component Numerator Core
      Gentamicin
      LP15747-6
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Susc
LP6870-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Isolate
LP7370-2
- System Core
  Isolate
  LP7370-2
- Super System
  NULL
Scale
OrdQn
LP7752-1
Method
Agar diffusion
LP6105-3

Basic Attributes

Class: ABXBACT
Type: Laboratory
First Released: Version 1.0
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Observation
Common Test Rank Get Info: 3036

Member of these Panels

LOINC	Long Common Name
50546-1	Bacterial susceptibility panel by Disk diffusion (KB)

Member of these Groups Get Info

LOINC Group	Group Name
LG41057-7	GentamicinSusc\|Isolate

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Gentamicin:Citlivost (mikroorganismy):Časový bod:Izolát:Ordinální nebo kvantitativní:Difúzní stanovení citlivosti na disku
de-DE	German (Germany)	Gentamicin:Empfindlichkeit (Mikroorganismen):Zeitpunkt:Isolat:Ordinal oder Quantitativ:Agardiffusionstest
el-GR	Greek (Greece)	Γενταμυκίνη:Susc:Pt:Απομονωμένο στέλεχος:OrdQn:Διάχυση με άγαρ Synonyms: ABXBACT OrdQn Pt Susc Απομονωμένο στέλεχος Γενταμυκίνη Διάχυση με άγαρ
es-AR	Spanish (Argentina)	gentamicina:susceptibilidad:punto en el tiempo:cepa clínica:ordinal o cuantitativo:difusión en agar
es-ES	Spanish (Spain)	Gentamicina:Susceptibilidad:Punto temporal:Aislado:Ordinal Cuantitativo:Difusión en disco; Kirby Bauer
es-MX	Spanish (Mexico)	Gentamicina:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal Cuantitativo:Difusión de disco (KB)
fr-CA	French (Canada)	Gentamicine:Susceptibilité:Temps ponctuel:Isolat:Quantitatif ou ordinal:Diffusion sur plaques
fr-FR	French (France)	Gentamicine:Sensibilité:Ponctuel:Isolat:Alphanumérique:Diffusion gel Agar
fr-BE	French (Belgium)	Gentamicine:Susceptibilité:Temps ponctuel:Isolat:Quantitatif ou ordinal:Diffusion sur plaques Synonyms: Diffusion en agar, précipitation en agar
it-IT	Italian (Italy)	Gentamicina:Susc:Pt:Isolato:OrdQn:Agar diffusione Synonyms: Disco diffusione (KB) Kirby-Bauer Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici
ko-KR	Korean (Korea, Republic Of)	겐타마이신:감수성:검사시점:분리주:정량 or 순위척도:우무확산
nl-NL	Dutch (Netherlands)	gentamicine:gevoeligheid:moment:isolaat:ordinaal-kwantitatief:agardiffusie
pl-PL	Polish (Poland)	Gentamycyna:wrażliwość:punkt w czasie:izolat:uporządkowany ilościowy:dyfuzja w żelu Synonyms: wrażliwość (mikroorganizmów)
pt-BR	Portuguese (Brazil)	Gentamicina:Susc:Pt:Isolado:OrdQn:Difusão em agar (disco) Synonyms: c213; Gent; Garamycin; Genj; Genirr; Susceptibility; Susceptibilty; Sus; Suscept; Susceptibilities; Point in time; Random; Islt; Isol; KB; Kirby-bauer; Disk diffusion; ANTIBIOTIC SUSCEPTIBILITIES
tr-TR	Turkish (Turkey)	Gentamisin:Duyr:Zmlı:İzolat:SrlKant:Agar difüzyon
zh-CN	Chinese (China)	庆大霉素:抗生素敏感性:时间点:分离株:定量型或序数型:琼脂扩散法 Synonyms: KB 法;Kirby-bauer 法;平皿扩散;平皿扩散法;琼脂平皿扩散;琼脂平皿扩散法;琼脂扩散;琼脂板扩散;琼脂板扩散法分离物;分离菌;分离菌株;隔离种群抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类时刻;随机;随意;瞬间正泰霉素;艮他霉素

Example Units

Unit	Source
mm	Example UCUM Units
mm	REGENSTRIEF

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=268-3

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.