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Part Description

LP15747-6   Gentamicin
Gentamicin is an aminoglycoside antibiotic, which has a bactericidal mode of action binding to the ribosome and various ribozymes to inhibit protein synthesis. Gentamicin is a hydrophilic molecule and is considered to have limited capacity to penetrate eukaryotic cells. Administered intravenously or intramuscularly, gentamicin is used to treat many bacterial infections, particularly gram-negative organisms such as meningitis, and infections of the blood, abdomen, lungs, skin, bones, joints and urinary tract, and is often used to treat severe cases of tularemia and the plague. The effect of gentamicin is mediated through the production of reactive oxygen species (ROS), which causes destablization of iron-sulfur (Fe-S) clusters and generates toxic, bactericidal compounds through the Fenton reaction. Gentamicin may cause kidney, nerve and severe hearing problems. More common side effects include nausea, headache, fever, rash and hoarseness. PMID: 26503658 [MedlinePlus Drug:a682275] Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Gentamicin:Titr:Pt:Isolate+Ser:SemiQn:SBT
Long Common Name
Gentamicin [Susceptibility] by Serum bactericidal titer
Short Name
Gentamicin Titr SBT
Display Name
Gentamicin SBT (Isol+S)
Consumer Name Alpha Get Info
Susceptibility to Gentamicin

Part Model Get Info

  • Component
    Gentamicin
    LP15747-6
    • Analyte
      Gentamicin
      LP15747-6
      • Component Numerator
        Gentamicin
        LP15747-6
        • Component Numerator Core
          Gentamicin
          LP15747-6
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Titr
    LP6881-9
  • Time
    Pt
    LP6960-1
  • System
    Isolate+Ser
    LP7371-0
    • System Core
      Isolate+Ser
      LP7371-0
    • Super System
      NULL
       
  • Scale
    SemiQn
    LP436123-6
  • Method
    SBT
    LP6501-3

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.75 (MAJ)
Order vs. Observation
Observation

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Gentamicin:Arbitrární koncentrace (titr):Časový bod:Izolát a sérum:Semikvantitativní:Sérový titr baktericidních látek
de-DEGerman (Germany)Gentamicin:Titer:Zeitpunkt:Isolat + Serum:Semiquantitativ:Bakterizide Aktivität im Serum
Synonyms: SBA
el-GRGreek (Greece)Γενταμυκίνη:Titr:Pt:Απομονωμένο στέλεχος+Ορός:Ημιποσοτική:SBT
Synonyms: ABXBACT Pt SBT Titr Απομονωμένο στέλεχος Απομονωμένο στέλεχος+Ορός Γενταμυκίνη Ημιποσοτική Ορός
es-ARSpanish (Argentina)gentamicina:susceptibilidad:punto en el tiempo:cepa clínica+suero:ordinal:determinación de título bactericida en suero
es-ESSpanish (Spain)Gentamicina:Titulo / Factor de dilución:Punto temporal:Aislado y Suero:Semicuantitativo:Títulos séricos bactericidas
Synonyms: Semicuantitativo
es-MXSpanish (Mexico)Gentamicina:Título:Punto temporal:Aislado y suero:Cuantitativo:Título bactericida en suero
fr-CAFrench (Canada)Gentamicine:Titre:Temps ponctuel:Isolat+Sérum:SemiQn:Pouvoir bactéricide du sérum
fr-FRFrench (France)Gentamicine:Titre:Ponctuel:Isolat+Sérum:Semi-Quantitatif:Pouvoir bactéricide du sérum
it-ITItalian (Italy)Gentamicina:Titr:Pt:Isolato+Siero:SemiQn:SBT
Synonyms: Isolato & Siero Prova battericida del siero Punto nel tempo (episodio) Siero Suscettibilità agli antibiotici Titolo
ko-KRKorean (Korea, Republic Of)겐타마이신:감수성:검사시점:분리주+혈청:순위척도:혈청 살균 역가
nl-NLDutch (Netherlands)gentamicine:titer:moment:isolaat en serum:semikwantitatief:serum bacteriocide titer
Synonyms: SBT
pl-PLPolish (Poland)Gentamycyna:miano:punkt w czasie:izolat i surowica:półilościowy:miano bakteriobójcze surowicy
pt-BRPortuguese (Brazil)Gentamicina:Título:Pt:Isolado/Soro:Qn:Teste bactericida do soro
Synonyms: c213; Gent; Garamycin; Genj; Genirr; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Islt; Isol; Quantitative; QNT; Quant; Quan; Serum Bactericidal Titer; Serum killing test; ANTIBIOTIC SUSCEPTIBILITIES
zh-CNChinese (China)庆大霉素:滴定度:时间点:分离株+血清:半定量型:血清杀菌滴度法
Synonyms: SBT SBT 法;血清杀灭试验;Serum killing test;SKT;血清杀灭试验法;血清杀菌滴度;血清杀菌滴度;Serum Bactericidal Titer;SBT;血清杀菌试验;血清杀菌试验法 分离株 & 血清;分离株与血清 分离物;分离菌;分离菌株;隔离种群 基于序列的分型（Sequence based typing，SBT） 基于序列的型别分析 基于序列的型别鉴定 基于序列的类型分析 基于序列的类型鉴定 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 正泰霉素;艮他霉素

Example Units

UnitSource
{titer}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=269-1