Version 2.77

Part Description

LP16758-2   SCL-70 extractable nuclear
Topoisomerase I (also known as Scl-70) is a nuclear enzyme that plays a role in releasing tension that is introduced in double-stranded DNA during DNA replication by transiently cleaving and rejoining one strand of the DNA duplex. Anti-Scl-70 autoantibodies are a marker of systemic sclerosis as well as other autoimmune diseases, including systemic lupus erythematosus (SLE). In patients with systemic sclerosis, anti-SCL-70 may be associated with more severe disease, and in patients with SLE, anti-SCL-70 suggests an increased risk of pulmonary hypertension and renal involvement. In general, anti-SCL-70 antibody status may help with diagnosis, treatment planning and prognosis in patients with connective tissue disease. PMID: 11229469 Source: Regenstrief LOINC, PMID: 11229469

Fully-Specified Name

Component
SCL-70 extractable nuclear Ab
Property
ACnc
Time
Pt
System
Ser
Scale
Qn
Method
IA

Additional Names

Short Name
ENA Scl70 Ab Ser IA-aCnc
Display Name
SCL-70 extractable nuclear Ab IA Qn (S)
Consumer Name Alpha Get Info
SCL-70 extractable nuclear antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.00
Last Updated
Version 2.73
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
2197

Member of these Groups Get Info

LOINC Group Group Name
LG10098-8 SCL-70 extractable nuclear Ab|ACnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Scl-70 AK EIA
de-DE German (Germany) SCL-70 extrahierbarer nukleärer Ak:Arbiträre Konzentration:Zeitpunkt:Serum:Quantitativ:Immunoassay
Synonyms: Scl-70
es-AR Spanish (Argentina) SCL-70 nuclear extraíble:concentración arbitraria:punto en el tiempo:suero:cuantitativo:enzimoinmunoanálisis
es-ES Spanish (Spain) Antígeno nuclear extraíble SCL-70 Anticuerpos:Concentración arbitraria:Punto temporal:Suero:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Ab nuclear extraíble SCL-70:Concentración arbitraria:Punto temporal:Suero:Cuantitativo:Inmunoensayo
fr-CA French (Canada) SCL-70 nucléaire soluble , Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
fr-FR French (France) SCL-70 anticorps:Arbitraire/Volume:Ponctuel:Sérum:Numérique:Immunoanalyse
fr-BE French (Belgium) SCL-70 nucléaire soluble Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
Synonyms: Anticorps
it-IT Italian (Italy) Nucleare estraibile SCL-70 Ab:ACnc:Pt:Siero:Qn:IA
Synonyms: anticorpo Concentrazione Arbitraria ENA Immunoassay Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
ko-KR Korean (Korea, Republic Of) SCL-70 추출성 핵 항체:임의농도:검사시점:혈청:정량:효소면역측정법
nl-NL Dutch (Netherlands) SCL-70 extraheerbare nucleaire As:eenheid/volume:moment:serum:kwantitatief:immunoassay
Synonyms: antistof; antilichaam IA
pl-PL Polish (Poland) SCL-70 rozpuszczalny jądrowy Ab:stężenie w jednostkach umownych:punkt w czasie:surowica:ilościowy:metoda immunologiczna
Synonyms: Przeciwciała do rozpuszczalnego antygenu jądrowego Przeciwciała przeciwjądrowe SCL-70 rozpuszczalny jądrowy
pt-BR Portuguese (Brazil) SCL-70 Ac:ACnc:Pt:Soro:Qn:Imunoensaio
Synonyms: ; ENA Scl70; Scleroderma Ac; ANA; ANF; NA; Antinuclear antibody; Nuc; Arbitrary concentration; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
ru-RU Russian (Russian Federation) SCL-70 экстрагируемый ядерный Ат:ПроизвКонц:ТчкВрм:Сыв:Колич:IA
Synonyms: Антитело Количественный Произвольная концентрация Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) SCL-70 özütlenebilir nükleer Ab:SçKons:Zmlı:Ser:Kant:İA
Synonyms: Ak Çekirdek İmmünölçüm, immünoassay
zh-CN Chinese (China) SCL-70 可提取性核 抗体:任意型浓度:时间点:血清:定量型:免疫测定法
Synonyms: Ab;自身抗体 ANA ENA Ab ENA SCL-70 Ab ENA SCL-70 抗体 ENA SCL-70;SCL-70 可提取性核 Ag;SCL-70 可提取性核抗原;可提取性核抗原 SCL-70;皮硬化症 Ab;皮硬化症抗体;硬皮病 Ab;硬皮病抗体;硬皮症 Ab;硬皮症抗体 ENA 抗体 ENA;可提取性核 Ag;可提取性核抗原;可提取性核抗原(Extractable Nuclear Antigen,ENA);可提取性细胞核;可提取性细胞核 Ag;可提取性细胞核抗原;盐水可提取性核 Ag;盐水可提取性核抗原;盐水可提取性细胞核 Ag;盐水可提取性细胞核抗原 NA SCL-70 可提取性核 Ab SCL-70 可提取性核 Ag Ab SCL-70 可提取性核抗原抗体 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 可提取性核 Ab 可提取性核 Ag 之 Ab 可提取性核抗原 SCL-70 Ab 可提取性核抗原 SCL-70 抗体 可提取性核抗原之抗体 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 抗 ENA 抗可提取性核 Ag 抗可提取性核抗原 抗核 Ab 抗核抗体 抗核抗体(Antinuclear antibody,ANA) 时刻;随机;随意;瞬间 核;胞核 皮硬化症 硬皮病 硬皮病(Scleroderma,SCL) 硬皮症 细胞核 Ab 胞核 Ab 胞核抗体 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目(非微生物学);血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验(非微生物学);血清学试验类 (非微生物学);血清类

Example Units

Unit Source
[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=26975-3