26975-3

SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

Active

Part Description

LP16758-2 SCL-70 extractable nuclear
Topoisomerase I (also known as Scl-70) is a nuclear enzyme that plays a role in releasing tension that is introduced in double-stranded DNA during DNA replication by transiently cleaving and rejoining one strand of the DNA duplex. Anti-Scl-70 autoantibodies are a marker of systemic sclerosis as well as other autoimmune diseases, including systemic lupus erythematosus (SLE). In patients with systemic sclerosis, anti-SCL-70 may be associated with more severe disease, and in patients with SLE, anti-SCL-70 suggests an increased risk of pulmonary hypertension and renal involvement. In general, anti-SCL-70 antibody status may help with diagnosis, treatment planning and prognosis in patients with connective tissue disease. PMID: 11229469 Source: Regenstrief LOINC, PMID: 11229469

LOINC Names Get Info

Fully-Specified Name: SCL-70 extractable nuclear Ab:ACnc:Pt:Ser:Qn:IA
Long Common Name: SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
Short Name: ENA Scl70 Ab Ser IA-aCnc
Display Name: SCL-70 extractable nuclear Ab IA Qn (S)
Consumer Name Alpha Get Info: SCL-70 extractable nuclear antibody, Blood

Part Model Get Info

Component
SCL-70 extractable nuclear Ab
LP39721-3
- Analyte
  SCL-70 extractable nuclear Ab
  LP39721-3
  - Component Numerator
    SCL-70 extractable nuclear Ab
    LP39721-3
    - Component Numerator Core
      SCL-70 extractable nuclear
      LP16758-2
    - Component Numerator Core Suffix
      Ab
      LP20667-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
ACnc
LP6773-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Qn
LP7753-9
Method
IA
LP217197-5

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.00
Last Updated: Version 2.73 (MIN)
Change Reason: The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 2197

Member of these Groups Get Info

LOINC Group	Group Name
LG10098-8	SCL-70 extractable nuclear Ab\|ACnc\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Antinukleární protilátky SCL-70 extrahovatelné:Arbitrární koncentrace:Časový bod:Sérum:Kvantitativní:Imunoanalýza
de-AT	German (Austria)	Synonyms: Scl-70 Antikörper EIA
de-DE	German (Germany)	SCL-70 extrahierbarer nukleärer Ak:Arbiträre Konzentration:Zeitpunkt:Serum:Quantitativ:Immunoassay Synonyms: Scl-70
el-GR	Greek (Greece)	Εκχυλίσιμα πυρηνικά SCL-70 Αντίσωμα:ACnc:Pt:Ορός:Qn:IA Synonyms: ACnc IA Pt Qn SERO Αντίσωμα Εκχυλίσιμα πυρηνικά Εκχυλίσιμα πυρηνικά SCL-70 Ορός Πυρηνικό
es-AR	Spanish (Argentina)	SCL-70 nuclear extraíble:concentración arbitraria:punto en el tiempo:suero:cuantitativo:enzimoinmunoanálisis
es-ES	Spanish (Spain)	Antígeno nuclear extraíble SCL-70 Anticuerpos:Concentración arbitraria:Punto temporal:Suero:Qn:IA Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Ab nuclear extraíble SCL-70:Concentración arbitraria:Punto temporal:Suero:Cuantitativo:Inmunoensayo
fr-CA	French (Canada)	SCL-70 nucléaire soluble, Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
fr-FR	French (France)	SCL-70 Ac:Arbitraire/Volume:Ponctuel:Sérum:Numérique:Immunoanalyse
fr-BE	French (Belgium)	SCL-70 nucléaire soluble Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA Synonyms: Anticorps
it-IT	Italian (Italy)	Nucleare estraibile SCL-70 Ab:ACnc:Pt:Siero:Qn:IA Synonyms: anticorpo Concentrazione Arbitraria ENA Immunoassay Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
ko-KR	Korean (Korea, Republic Of)	SCL-70 추출성 핵 항체:임의농도:검사시점:혈청:정량:효소면역측정법
nl-NL	Dutch (Netherlands)	SCL-70 extraheerbare nucleaire As:eenheid/volume:moment:serum:kwantitatief:immunoassay Synonyms: antistof; antilichaam IA
pl-PL	Polish (Poland)	SCL-70 rozpuszczalny jądrowy Ab:stężenie w jednostkach umownych:punkt w czasie:surowica:ilościowy:metoda immunologiczna Synonyms: Przeciwciała do rozpuszczalnego antygenu jądrowego Przeciwciała przeciwjądrowe SCL-70 rozpuszczalny jądrowy
pt-BR	Portuguese (Brazil)	SCL-70 Ac:ACnc:Pt:Soro:Qn:Imunoensaio Synonyms: ; ENA Scl70; Scleroderma Ac; ANA; ANF; NA; Antinuclear antibody; Nuc; Arbitrary concentration; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
ru-RU	Russian (Russian Federation)	SCL-70 экстрагируемый ядерный Ат:ПроизвКонц:ТчкВрм:Сыв:Колич:IA Synonyms: Антитело Количественный Произвольная концентрация Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	SCL-70 özütlenebilir nükleer Ab:SçKons:Zmlı:Ser:Kant:İA Synonyms: Ak Çekirdek İmmünölçüm, immünoassay
zh-CN	Chinese (China)	SCL-70 可提取性核抗体:任意型浓度:时间点:血清:定量型:免疫测定法 Synonyms: Ab;自身抗体 ANA ENA Ab ENA SCL-70 Ab ENA SCL-70 抗体 ENA SCL-70;SCL-70 可提取性核 Ag;SCL-70 可提取性核抗原;可提取性核抗原 SCL-70;皮硬化症 Ab;皮硬化症抗体;硬皮病 Ab;硬皮病抗体;硬皮症 Ab;硬皮症抗体 ENA 抗体 ENA;可提取性核 Ag;可提取性核抗原;可提取性核抗原（Extractable Nuclear Antigen，ENA）;可提取性细胞核;可提取性细胞核 Ag;可提取性细胞核抗原;盐水可提取性核 Ag;盐水可提取性核抗原;盐水可提取性细胞核 Ag;盐水可提取性细胞核抗原 NA SCL-70 可提取性核 Ab SCL-70 可提取性核 Ag Ab SCL-70 可提取性核抗原抗体任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验可提取性核 Ab 可提取性核 Ag 之 Ab 可提取性核抗原 SCL-70 Ab 可提取性核抗原 SCL-70 抗体可提取性核抗原之抗体可用数量表示的;定量性;数值型;数量型;连续数值型标尺抗 ENA 抗可提取性核 Ag 抗可提取性核抗原抗核 Ab 抗核抗体抗核抗体（Antinuclear antibody，ANA）时刻;随机;随意;瞬间核;胞核皮硬化症硬皮病硬皮病（Scleroderma，SCL）硬皮症细胞核 Ab 胞核 Ab 胞核抗体血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit	Source
[arb'U]/mL	Example UCUM Units

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.