Version 2.78

Part Description

LP15763-3   Gramicidin D
Gramicidin is a heterogeneous mixture of six antibiotic compounds, Gramicidins A, B and C, making up 80%, 6%, and 14% respectively, all of which are obtained from the soil bacterial species Bacillus brevis and called collectively Gramicidin D. Gramicidin D are linear pentadecapeptides; that is chains made up of 15 amino acids. This is in contrast to Gramicidin S which is a cyclic peptide chain. Gramicidin is active against Gram-positive bacteria, except for the Gram-positive bacilli, and against select Gram-negative organisms, such as Neisseria bacteria. Its therapeutic use is limited to topical application as it induces hemolysis in lower concentrations than bacteria cell death, thus cannot be administered internally. The exterior epidermis is composed of dead cells, thus applying it to the surface of the skin will not cause harm. It is used primarily as a topical antibiotic and is one of the three constituents of consumer antibiotic Neosporin Ophthalmic Solution. In 1939 the French-American microbiologist René Dubos isolated the substance tyrothricin and later showed that it was composed of two substances, gramicidin (20%) and tyrocidine (80%). These were the first antibiotics to be manufactured commercially. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Gramicidin D

Fully-Specified Name

Component
Gramicidin D
Property
Susc
Time
Pt
System
Isolate
Scale
OrdQn
Method
MIC

Additional Names

Short Name
Gramicidin D Islt MIC
Display Name
Gramicidin D MIC [Susc]
Consumer Name Alpha Get Info
Susceptibility to Gramicidin D

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.19
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
50545-3 Bacterial susceptibility panel by Minimum inhibitory concentration (MIC)

Member of these Groups Get Info

LOINC Group Group Name
LG41059-3 Gramicidin DSusc|Isolate

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Gramicidin D:Empfindlichkeit (Mikroorganismen):Zeitpunkt:Isolat:Ordinal oder Quantitativ:Minimale Hemmkonzentration (MHK)
es-AR Spanish (Argentina) gramicidina D:susceptibilidad:punto en el tiempo:cepa clínica:ordinal o cuantitativo:concentración inhibitoria mínima
es-ES Spanish (Spain) Gramicidina D:Susceptibilidad:Punto temporal:Aislado:Ordinal Cuantitativo:Concentración mínima inhibitoria (CMI)
es-MX Spanish (Mexico) Gramicidina D:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal Cuantitativo:Concentración mínima inhibitoria (MIC)
fr-CA French (Canada) Gramicidine D:Susceptibilité:Temps ponctuel:Isolat:Quantitatif ou ordinal:CMI
fr-FR French (France) Gramicidine D:Sensibilité:Ponctuel:Isolat:Alphanumérique:CMI
fr-BE French (Belgium) Gramicidine D:Susceptibilité:Temps ponctuel:Isolat:Quantitatif ou ordinal:CMI
it-IT Italian (Italy) Gramicidina D:Susc:Pt:Isolato:OrdQn:MIC
Synonyms: Concentrazione minima inibitoria Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici
ko-KR Korean (Korea, Republic Of) 그라미시딘 D:감수성:검사시점:분리주:정량 or 순위척도:억제최소농도
nl-NL Dutch (Netherlands) gramicidine D:gevoeligheid:moment:isolaat:ordinaal-kwantitatief:minimaal inhiberende concentratie
Synonyms: MIC
pt-BR Portuguese (Brazil) Gramicidina D:Susc:Pt:Isolado:OrdQn:Concentração inibitória mínima
Synonyms: Neosporin; Argicillin; AK-spore; ALBA-3; Rhesus; Rh; Susceptibility; Susceptibilty; Sus; Suscept; Susceptibilities; Point in time; Random; Islt; Isol; Minimum inhibitory concentration; ANTIBIOTIC SUSCEPTIBILITIES
ru-RU Russian (Russian Federation) Грамицидин D:Чув:ТчкВрм:Изолят:ПорКол:МИК
Synonyms: Минимальная ингибирующая концентрация (МИК) Порядковый или Количественный Точка во времени;Момент Чувствительность (микроорганизмов)
tr-TR Turkish (Turkey) Gramisidin D:Duyr:Zmlı:İzolat:SrlKant:MIC
zh-CN Chinese (China) 短杆菌肽 D:抗生素敏感性:时间点:分离株:定量型或序数型:最小抑菌浓度法
Synonyms: Rh;Rhesus;恒河猴;猕猴;罗猴 分离物;分离菌;分离菌株;隔离种群 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 最低抑制浓度;最低抑制浓度法;最低抑菌浓度;最低抑菌浓度法;最小抑制浓度;最小抑制浓度法;最小抑菌浓度;Minimum Inhibitory Concentration;MIC 羟甲基短杆菌肽

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=271-7