27100-7
Probenecid [Mass/volume] in Serum or Plasma
Active
Part Descriptions
LP16260-9 Probenecid
Probenecid is a uricosuric drug, primarily used in treating gout or hyperuricemia, that increases uric acid removal in the urine. Probenecid also decreases the renal excretion of some drugs. In one study, probenecid was shown to more than double a patient's exposure to oseltamivir (trade name Tamiflu), an antiviral drug used to combat influenza. This is significant because nations are currently stockpiling oseltamivir in anticipation of an influenza pandemic, and the drug is in short supply. During World War II, probenecid was used to extend limited supplies of penicillin, and is still currently used to increase antibiotic concentrations in serious infections. It has also found use as a masking agent by athletes attempting to get away with using performance enhancing drugs. In the kidneys it is filtered at the glomerulus, secreted in the proximal tubule and reabsorbed in the distal tubule. Probenecid's exact mechanism of action in the kidneys' nephrons is unknown.
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Source: Wikipedia
, Probenecid (Wikipedia)
LP16260-9 Probenecid
The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- Probenecid
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- Probenecid [Mass/volume] in Serum or Plasma
- Short Name
- Probenecid SerPl-mCnc
- Display Name
- Probenecid [Mass/Vol]
- Consumer Name Alpha Get Info
- Probenecid, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.00
- Last Updated
- Version 2.70 (MIN)
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Προβενεσίδη: Synonyms: MCnc |
| es-AR | Spanish (Argentina) | probenecid: |
| es-ES | Spanish (Spain) | Probenecid: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Probenecid: |
| et-EE | Estonian (Estonia) | Probenetsiid: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Probénécide: |
| fr-FR | French (France) | Probénécide: |
| fr-BE | French (Belgium) | Probénécide: |
| it-IT | Italian (Italy) | Probenecid: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 프로베네시드: |
| nl-NL | Dutch (Netherlands) | probenecide: |
| pt-BR | Portuguese (Brazil) | Probenecida: Synonyms: Benemid; |
| ru-RU | Russian (Russian Federation) | Пробенецид: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Probenesid: |
| zh-CN | Chinese (China) | 丙磺舒: Synonyms: 二丙苯磺胺; |
Example Units
| Unit | Source |
|---|---|
| ug/mL | Example UCUM Units |
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