Version 2.78

Part Descriptions

LP16472-0   Interleukin 4
Interleukin-4, abbreviated IL-4, is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4. The cell that initially produces IL-4, thus inducing Th0 differentiation, has not been identified, but recent studies suggest that basophils may be the effector cell.

It has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. IL-4 induces B-cell class switching to IgE, and up-regulates MHC class II production. Overproduction of IL-4 is associated with allergies. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP16472-0   Interleukin 4
The Interleukins belong to the family termed cytokines. They are peptides used by immune and inflammatory cells to communicate and control cell operations. The cytokines have some similar actions to the Growth Factors but Growth Factors regulate proliferation of non-immune cells. Interleukin 4 is a 20,000 molecular weight glycoprotein originally called T Cell Growth Factor along with Interleukin 2. It is released primarily by activated T Cells and mast cells. Its primary target cells are T and B cells, macrophage/monocytes, and mast cells. Interleukin 4 activates B cell differentiation and immunoglobulins prior to action of Interleukin 6. It is also a co-stimulator along with anti-immunoglobulin antibodies of B cell proliferation. Interleukin 4 is bound to receptors located on activated T cells, resting and activated B cells, macrophages, and mast cells. Source: Inter Science Institute, Inter Science Institute

Fully-Specified Name

Component
Interleukin 4
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Il4 SerPl-mCnc
Display Name
Interleukin 4 [Mass/Vol]
Consumer Name Alpha Get Info
Interleukin 4, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.00
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
6979

Member of these Panels

LOINC Long Common Name
82335-1 Cytokines panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Interleukin-4
de-DE German (Germany) Interleukin-4:Massenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:
es-AR Spanish (Argentina) interleucina 4:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ES Spanish (Spain) Interleukina 4:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Interleucina 4:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE Estonian (Estonia) Interleukiin 4:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA French (Canada) Interleukine 4:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Interleukine-4:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Interleukine 4:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: Il4
it-IT Italian (Italy) Interleuchina 4:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR Korean (Korea, Republic Of) 인터루킨 4:질량농도:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) interleukine 4:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Interleucina 4:MCnc:Pt:Sor/Plas:Qn:
Synonyms: ; Il4; IL-4; B-Cell Growth Factor-I; B-Cell Stimulatory Factor-1; Binetrakin; IL4; Mast Cell Growth Factor-2; B-Cell Proliferating Factor; B-Cell Stimulating Factor-1; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; IL; Chemistry
ru-RU Russian (Russian Federation) Интерлейкин 4:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) İnterlökin 4:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 白细胞介素 4:质量浓度:时间点:血清/血浆:定量型:
Synonyms: B 细胞刺激因子-1;B 细胞刺激性因子-1;B 细胞增殖因子;B 细胞生长因子-I;Binetrakin;B-细胞刺激因子-1;B-细胞刺激性因子-1;B-细胞增殖因子;B-细胞生长因子-I;Il4;IL-4;白介素 4;白介素-4;白细胞介素-4;肥大细胞生长因子-2 IL 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积) 白介 白介素 白细胞介素（Interleukin，白介素，IL） 血清或血浆

Example Units

Unit Source
pg/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=27161-9