28601-3

Hydroxyproline/Creatinine [Ratio] in Urine

Active

Part Descriptions

LP15650-2   Hydroxyproline
4-Hydroxyproline, or hydroxyproline (C 5 H 9 O 3 N), is an uncommon amino acid, abbreviated as HYP. Hydroxyproline differs from proline by the presence of a hydroxyl (OH) group attached to the C (gamma) atom.

Proline hydroxylation requires ascorbic acid (vitamin C). The most obvious, first effects (gingival and hair problems) of absence of ascorbic acid in humans come from the resulting defect in hydroxylation of proline residues of collagen, with reduced stability of the collagen molecule, causing scurvy.
Increased serum and urine levels of hydroxyproline have also been demonstrated in Paget's disease. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Hydroxyproline (Wikipedia)

LP15650-2   Hydroxyproline
Hydroxyproline is a hydrophilic amino acid with uncharged polar groups and is a major component of collagen. Increased with hydroxyprolinemia and iminoglycinuria. Decreased with chronic Vitamin C deficiency. (Information from ARUP Laboratories 9/14/06) Source: Regenstrief Institute

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Fully-Specified Name

Component

Hydroxyproline/Creatinine

Property

Ratio

Time

Pt

System

Urine

Scale

Qn

Method

Additional Names

Short Name

OH-Proline/Creat Ur-Rto

Display Name

Hydroxyproline/Creatinine (U) [Ratio]

Consumer Name Alpha Get Info

Hydroxyproline/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.00

Last Updated

Version 2.73

Order vs. Observation

Both

Common Test Rank Get Info

6368

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• Chemistry
• CR
• Crea
• Creat
• Hydroxylproline
• Hydroxyprol
• Hydroxy-proline
• Hydrxprol
• Hydrxproln
• Hydrxyprln
• Hyp
• Ohpro
• OH-Proline
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• Ratios
• Rto
• UA
• UCr
• UR
• Urn

Example Units

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CodeSystem lookup

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.