Version 2.80

Part Descriptions

LP17236-8   cloZAPine
Clozapine (sold as Clozaril ®, Leponex ®, Fazaclo ®) was the first of the atypical antipsychotics to be developed. It was approved by the United States Food and Drug Administration (FDA) in 1989 and is the only FDA-approved medication indicated for treatment-resistant schizophrenia and for reducing the risk of suicidal behaviour in patients with schizophrenia. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Clozapine (Wikipedia)

LP17236-8   cloZAPine
A tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Agranulocytosis is a major adverse effect associated with administration of this agent. Source: National Library of Medicine, MeSH 2006

LP20176-1   trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Trough levels for therapeutic drug monitoring

Fully-Specified Name

Component
cloZAPine^trough
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Long Common Name
cloZAPine [Mass/volume] in Serum or Plasma --trough
Short Name
cloZAPine Trough SerPl-mCnc
Display Name
cloZAPine trough [Mass/Vol]
Consumer Name Alpha Get Info
cloZAPine trough, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.03
Last Updated
Version 2.70 (MIN)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Κλοζαπίνη^ελάχιστα επίπεδα:MCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: MCnc
es-AR Spanish (Argentina) clozapina^mínima:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ES Spanish (Spain) Clozapina^Valle monitorización terapéutica de fármacos:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) cloZAPine ^ comedero:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE Estonian (Estonia) Klosapiin^baas:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA French (Canada) Clozapine^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: #REF!
fr-FR French (France) Clozapine taux résiduel:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Clozapine^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: Minimum, nadir
it-IT Italian (Italy) Clozapina^valore minimo:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM
ko-KR Korean (Korea, Republic Of) 클로자핀^최저 약물 농도 시간:질량농도:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) clozapine^dalspiegel:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Clozapina^basal:MCnc:Pt:Sor/Plas:Qn:
Synonyms: Clozaril; Pre; Predose; Pre-dose; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU Russian (Russian Federation) Клозапин^остаточная концентрация:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Klozapine^en düşük:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 氯氮平^波谷:质量浓度:时间点:血清/血浆:定量型:
Synonyms: 一剂药物的初始剂量;初始剂量;剂量药物的初始剂量;前剂量;曲线上的最小值;最低点;本底剂量;治疗药物监测 - 波谷;预剂量 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 氯扎平 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

Unit Source
ng/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=29370-4