29527-9
Citrate/Creatinine [Molar ratio] in Urine
Active
Part Descriptions
LP14741-0 Citrate
A citrate is an ionic form of citric acid, such as C3 H5 O(COO)3 3ˆ', that is, citric acid minus three hydrogen ions. Citrates are compounds containing this group, either ionic compounds, the salts, or analogous covalent compounds, esters. An example of a salt is sodium citrate and an ester is trimethyl citrate. Because citric acid is a multifunctional acid, several intermediate ions exist: hydrogen citrate ion, HC6 H5 O7 2ˆ' and dihydrogen citrate ion, H2 C6 H5 O7 ˆ'. These may form salts as well, called acid salts. Salts of the hydrogen citrate ions are weakly acidic, whereas salts of the citrate ion itself (with an inert cation such as sodium ion) are weakly basic.
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Source: Wikipedia, Citrate (Wikipedia)
LP14741-0 Citrate
Citrate testing is used to diagnose renal tubular acidosis and evaluate kidney stone disease. Acid-base balance plays a critical role in citrate excretion. In acidosis, increased citrate utilization occurs and causes reduced citrate excretion. In alkalosis, citrate excretion increases. Hypocitruria promotes the formation of calcium kidney stones because citrate normally binds urinary calcium as a soluble calcium citrate salt. Hypocitruria may also have a role in uric acid stone formation. Citrate excretion is impaired by acidosis, hypokalemia, urinary tract infection, and a high animal protein/high acid-ash content diet. Urine citrate levels may also be decreased with severe muscular activity, hypoparathyroidism, diabetes, and chronic renal failure. Urine citrate levels may be increased with high carbohydrate diet, estrogen therapy, and Vitamin D use. Information from emedicine, "Hypocitraturia," by George Bennett Stackhouse IV, MD, and Medline Plus, accessed 2006 10 25
Source: Regenstrief Institute
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- Citrate/Creatinine
- Property
- SRto
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Short Name
- Citrate/Creat Ur-sRto
- Display Name
- Citrate/Creatinine (U) [Molar ratio]
- Consumer Name Alpha Get Info
- Citrate/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.03
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 9221
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 48797-5 | Organic acids panel - Urine |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Citrat/Kreatinin-Ratio /U |
| de-DE | German (Germany) | Citrat/Creatinin: |
| es-AR | Spanish (Argentina) | citrato/creatinina: |
| es-ES | Spanish (Spain) | Citrato/Creatinina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Citrato / Creatinina: |
| fr-CA | French (Canada) | Citrate/Créatinine: |
| fr-FR | French (France) | Citrate/créatinine: |
| fr-BE | French (Belgium) | Citrate/Créatinine: |
| it-IT | Italian (Italy) | Citrato/Creatinina: Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza |
| ko-KR | Korean (Korea, Republic Of) | 구연산/크레아티닌: |
| nl-NL | Dutch (Netherlands) | citraat/creatinine: Synonyms: kreatinine |
| pt-BR | Portuguese (Brazil) | Citrato/Creatinina: Synonyms: Citric acid; |
| ru-RU | Russian (Russian Federation) | Цитрат/Креатинин: Synonyms: Количественный Мольная доля; |
| tr-TR | Turkish (Turkey) | Sitrat/Kreatinin: Synonyms: SubsOranı |
| zh-CN | Chinese (China) | 柠檬酸/肌酐: Synonyms: CR; |
Example Units
| Unit | Source |
|---|---|
| mmol/mol | eCHN |
| mmol/mol cr | REGENSTRIEF |
| mmol/mol{creat} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- https:
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LOINC Copyright
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