29528-7

Hippurate/Creatinine [Molar ratio] in Urine

Active

Part Descriptions

LP15635-3 Hippurate
Hippuric acid (Gr. hippos, horse, ouron, urine), benzoyl glycocoll or benzoyl amidoacetic acid, C9 H9 NO3 or C6 H5 CONHCH2 CO2 H, is an organic acid found in the urine of horses and other herbivores. Its molecular weight is 179.175 and melting point range is 188-191ºC. High concentrations of hippuric acid can also indicate a toluene intoxication. It is excreted when many aromatic compounds, such as benzoic acid and toluene, are taken internally. Justus von Liebig in 1829 showed that it differed from benzoic acid, and in 1839 determined its constitution, while in 1873 Victor Dessaignes (Ann. 87, p. 325) synthesized it by the action of benzoyl chloride on zinc glycocollide. It is also formed by heating benzoic anhydride with glycine (Theodor Curtius, Ber., 1884, 17, p. 1662), and by heating benzamide with monochloroacetic acid. It crystallizes in rhombic prisms which are readily soluble in hot water, melt at 187°C. and decompose at about 240°C. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Hippurate (Wikipedia)

LP15635-3 Hippurate
Hippuric acid is biological renal marker used to monitor exposure to toluene or benzyl alchonol. Hippuric acid and methyl hippuric acid are the principal metabolities of toluene and xylene, respectively. Occupational exposure to these chemicals can be monitored by measuring urinary metabolite excretion.Typical excretion of hippuric acid in non-exposed patients is 1.0 g/g creatinine. Methyl hippuric acid is not found in non-exposed patients. Information from National Medical Service and Department of Health and Human Service, Centers for Disease Control and Prevention(CDC)-National Institute for Occupational Safety and Health(NIOSH), accessed 2007 07 23. Source: Regenstrief Institute

LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Fully-Specified Name

Component: Hippurate/Creatinine
Property: SRto
Time: Pt
System: Urine
Scale: Qn
Method

Additional Names

Long Common Name: Hippurate/Creatinine [Molar ratio] in Urine
Short Name: Hippurate/Creat Ur-sRto
Display Name: Hippurate/Creatinine (U) [Molar ratio]
Consumer Name Alpha Get Info: Hippurate/Creatinine, Urine

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.03
Last Updated: Version 2.73
Order vs. Observation: Both
Common Test Rank Get Info: 12549

Member of these Panels

LOINC	Long Common Name
48797-5	Organic acids panel - Urine

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	Hippurat/Creatinin:Stoffmengenverhältnis:Zeitpunkt:Urin:Quantitativ:
es-AR	Spanish (Argentina)	hipurato/creatinina:relación de concentración de la sustancia:punto en el tiempo:orina:cuantitativo:
es-ES	Spanish (Spain)	Hipurato/Creatinina:Relacion de Sustancia:Punto temporal:Orina:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Hipurato / Creatinina:Proporción de sustancia:Punto temporal:Orina:Cuantitativo:
fr-CA	French (Canada)	Hippurate/Créatinine:Ratio de substance:Temps ponctuel:Urine:Quantitatif:
fr-FR	French (France)	Hippurate/créatinine:Moles ratio:Ponctuel:Urine:Numérique:
fr-BE	French (Belgium)	Hippurate/Créatinine:Ratio de substance:Temps ponctuel:Urine:Quantitatif:
it-IT	Italian (Italy)	Ippurato/Creatinina:Srto:Pt:Urine:Qn: Synonyms: Acido Ippurico Livelli farmacologici e tossicologia Punto nel tempo (episodio) Rapporto di sostanza
ko-KR	Korean (Korea, Republic Of)	마뇨산/크레아티닌:물질구성비:검사시점:뇨:정량:
nl-NL	Dutch (Netherlands)	hippuraan/creatinine:molaire verhouding:moment:urine:kwantitatief: Synonyms: kreatinine
pt-BR	Portuguese (Brazil)	Hipurato/Creatinina:SCrto:Pt:Urina:Qn: Synonyms: Hipp; Hippuran; Toluene metAcolite; Benzyl alcohol metAcolite; Hippuric acid; HIP-REX; Hippramine; Hiprex; Urex; Urotractan; Creat; CR; sRto; Substance concentration ratio; Point in time; Random; UR; Urn; UA; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY; UCr
ru-RU	Russian (Russian Federation)	Гиппурат/Креатинин:МольОтн:ТчкВрм:Моча:Колич: Synonyms: Количественный Мольная доля;Молярная доля;Отношение концентраций Точка во времени;Момент
tr-TR	Turkish (Turkey)	Hippürat/Kreatinin:SOrn:Zmlı:İdrar:Kant: Synonyms: SubsOranı
zh-CN	Chinese (China)	马尿酸/肌酐:物质的量比率:时间点:尿液:定量型: Synonyms: CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 UCr 可用数量表示的;定量性;数值型;数量型;连续数值型标尺尿;小便;下泉尿液肌酐尿液肌酸酐尿肌酸酐时刻;随机;随意;瞬间毒品毒品类物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值甲苯代谢产物;苄醇代谢产物;苯甲醇代谢产物肌酸内酰胺药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类

Example Units

Unit	Source
mmol/mol cr	REGENSTRIEF
mmol/mol{creat}	Example UCUM Units

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