29590-7

Cytomegalovirus DNA [Mass/volume] (viral load) in Blood by Probe

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Part Description

LP14255-1 Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.https://www.cdc.gov/cmv/overview.html Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Cytomegalovirus DNA:MCnc:Pt:Bld:Qn:Probe
Long Common Name: Cytomegalovirus DNA [Mass/volume] (viral load) in Blood by Probe
Short Name: CMV DNA Bld Probe-mCnc
Display Name: CMV DNA Probe (Bld) [Mass/Vol]
Consumer Name Alpha Get Info: Cytomegalovirus (CMV), Blood

Part Model Get Info

Component
Cytomegalovirus DNA
LP37883-3
- Analyte
  Cytomegalovirus DNA
  LP37883-3
  - Component Numerator
    Cytomegalovirus DNA
    LP37883-3
    - Component Numerator Core
      Cytomegalovirus
      LP14255-1
    - Component Numerator Core Suffix
      DNA
      LP32416-7
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld
LP7057-5
- System Core
  Bld
  LP7057-5
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Probe
LP6459-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.03
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 5544

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Cytomegalovirus DNA:Hmotnostní koncentrace:Časový bod:Krev:Kvantitativní:Sonda
de-DE	German (Germany)	Cytomegalie-Virus DNA:Massenkonzentration:Zeitpunkt:Blut:Quantitativ:Sondendetektion Synonyms: CMV
el-GR	Greek (Greece)	Κυτταρομεγαλοϊός DNA:MCnc:Pt:Αίμα:Qn:Ανιχνευτής Synonyms: DNA MCnc MICRO Pt Qn Αίμα Ανιχνευτής Κυτταρομεγαλοϊός
es-AR	Spanish (Argentina)	ADN de citomegalovirus:concentración de masa:punto en el tiempo:sangre:cuantitativo:sonda
es-ES	Spanish (Spain)	Citomegalovirus ADN:Concentración de masa:Punto temporal:Sangre:Qn:Sonda de DNA Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	ADN de citomegalovirus:Concentración de masa:Punto temporal:Sangre:Cuantitativo:Investigacion
fr-CA	French (Canada)	Cytomégalovirus, ADN:Concentration de masse:Temps ponctuel:Sang:Quantitatif:Sonde
fr-FR	French (France)	Cytomégalovirus ADN:Masse/Volume:Ponctuel:Sang:Numérique:PCR
fr-BE	French (Belgium)	Cytomégalovirus ADN:Concentration de masse:Temps ponctuel:Sang:Quantitatif:Sonde Synonyms: CMV
it-IT	Italian (Italy)	Citomegalovirus DNA:MCnc:Pt:Sangue:Qn:Sonda Synonyms: Concentrazione di Massa Microbiologia Punto nel tempo (episodio) Sangue Sonda di DNA
ko-KR	Korean (Korea, Republic Of)	거대세포바이러스 디옥시리보핵산:질량농도:검사시점:전혈:정량:DNA 탐색자
nl-NL	Dutch (Netherlands)	Cytomegalovirus DNA:massa/volume:moment:bloed:kwantitatief:DNA-sonde
pl-PL	Polish (Poland)	Wirus cytomegalii DNA:stężenie masowe:punkt w czasie:krew:ilościowy:sonda Synonyms: Cytomegalowirus DNA Cytomeglaowirusa Kwas deoksyrybonukleinowy
pt-BR	Portuguese (Brazil)	Citomegalovírus DNA:MCnc:Pt:SgTotal:Qn:Sonda de DNA Synonyms: Deoxyribonucleic acid; CMV; Cytomgal; Cytomegalo virus; Mass concentration; Level; Point in time; Random; Blood; WB; Whole blood; Quantitative; QNT; Quant; Quan; Prb; DNA probe; Microbiology
ru-RU	Russian (Russian Federation)	Цитомегаловирус ДНК:МассКонц:ТчкВрм:Кр:Колич:Проба Synonyms: ДНК проба;ДНК зонд Количественный Кровь Массовая концентрация Точка во времени;Момент
tr-TR	Turkish (Turkey)	Cytomegalovirus DNA:KütlKons:Zmlı:Kan:Kant:Prob
zh-CN	Chinese (China)	巨细胞病毒 DNA:质量浓度:时间点:全血:定量型:DNA探针 Synonyms: CMV DNA CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒去氧核糖核酸;脱氧核糖核酸去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA）可用数量表示的;定量性;数值型;数量型;连续数值型标尺微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）时刻;随机;随意;瞬间水平;浓度;质量浓度(单位体积) 脱氧核糖核酸探针血;血液

Example Units

Unit	Source
pg/mL	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.