29647-5
Interferon beta Ab [Presence] in Serum or Plasma
Active
Part Descriptions
LP18172-4 Interferon.beta
Beta interferon is a recombinant protein which is chemically identical to or similar to endogenous interferon beta with antiviral and anti-tumor activities. Endogenous interferons beta are cytokines produced by nucleated cells (predominantly natural killer cells) upon exposure to live or inactivated virus, double-stranded RNA or bacterial products. These agents bind to specific cell-surface receptors, resulting in the transcription and translation of genes with an interferon-specific response element. The proteins so produced mediate many complex effects, including antiviral (the most important being inhibition of viral protein synthesis), antiproliferative and immune modulating effects. The recombinant therapeutic forms of interferon beta are interferon beta 1-a and interferon beta 1-b.
Source: National Cancer Institute
, Beta interferon
LP38708-1 Interferon.beta Ab
Highly elevated levels of neutralizing antibodies (NAbs >1:100) to interferon-beta used as therapy in patients with Multiple Sclerosis have been reported to correlate with predictable loss of interferon-beta bioactivity. In patients with elevated NAb levels from >1:20 to <1:100, interferon-beta bioactivity may still be present, but does not necessarily correlate to the exact NAb titer, and continued patient monitoring may be warranted. There is no apparent loss of interferon-beta bioactivity in patients who test positive in the binding antibody assay, but
negative for NAbs; however, continued patient monitoring may also be warranted in this instance as well.
Source: Quest Diagnostics Inc.
, Interferon-beta 1a (IFNB-1a) Antibody
Fully-Specified Name
- Component
- Interferon.beta Ab
- Property
- PrThr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Ord
- Method
Additional Names
- Long Common Name
- Interferon beta Ab [Presence] in Serum or Plasma
- Short Name
- IFN-B Ab SerPl Ql
- Display Name
- Interferon beta Ab Ql
- Consumer Name Alpha Get Info
- Interferon beta antibody, Blood
Example Answer List: LL360-9
Source: Regenstrief Institute| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.03
- Last Updated
- Version 2.73 (MIN)
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 12753
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Interferon.beta Ak: |
| el-GR | Greek (Greece) | Ιντερφερόνη.β Αντίσωμα: Synonyms: PrThr |
| es-AR | Spanish (Argentina) | anticuerpo contra interferón.beta 1: |
| es-ES | Spanish (Spain) | Interferon beta Anticuerpos: |
| es-MX | Spanish (Mexico) | Interferon.beta Ab: |
| et-EE | Estonian (Estonia) | Beetainterferoon antikehad: Synonyms: Järgarvuline Juhuslik Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Interféron.bêta, Ac: |
| fr-FR | French (France) | Interféron bêta anticorps: |
| fr-BE | French (Belgium) | Interféron.béta Ac: Synonyms: Anticorps IF If.béta |
| it-IT | Italian (Italy) | Interferone.beta Ab: Synonyms: anticorpo Interferone beta Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant |
| ko-KR | Korean (Korea, Republic Of) | 인터페론.베타 항체: |
| nl-NL | Dutch (Netherlands) | interferon.bèta As: Synonyms: antistof; |
| pt-BR | Portuguese (Brazil) | Interferon.beta Ac: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Интерферон.бета Ат: Synonyms: Антитело Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | İnterferon.beta Ab: Synonyms: Mevcut |
| zh-CN | Chinese (China) | 干扰素.beta 抗体: Synonyms: Ab; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=29647-5
Third Party Copyright
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LOINC Copyright
Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://